Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Jeegar, Patel"'
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Evaluation of the clinical molecule anti-human-PD-L1/IL-15 KD033 in the human-PD-1/PD-L1-expressing murine model demonstrates PD-L1 targeting of IL-15 in vivo
Autor: Stella A. Martomo, Jeegar Patel
Publikováno v: Cancer Immunology, Immunotherapy. 72:1941-1950
KD033 is a clinical-stage immunocytokine composed of a high-affinity anti-human-PD-L1 antibody and the human IL-15/ IL-15 receptor sushi-domain complex. We have previously shown that KD033-surrogate, the anti-mouse-PD-L1/IL-15 immunocytokine, was eff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::742bc3533dea2adafe2072b361c67720
https://doi.org/10.1007/s00262-022-03331-0
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9
Phase 1 Studies to Evaluate the Food Effect and Relative Bioavailability of Tablet and Capsule Formulations of Belumosudil in Healthy Adult Subjects
Autor: Olivier, Schueller, John, McDermott, Phil, Evans, Lauren, Lohmer, Anginelle, Alabanza, Jeegar, Patel
Publikováno v: Clinical Pharmacology in Drug Development. 11:807-814
Belumosudil is a selective Rho-associated coiled-coil containing protein kinase 2 inhibitor. A capsule formulation was used during early clinical development of belumosudil; it was later replaced by a tablet formulation, which mimicked the capsule's
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa637ddf34b13f54f0c35b46adc0ca7
https://doi.org/10.1002/cpdd.1083
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