Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeeba Kuriakose"'
A phospho-tyrosine-based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity
Autor:
Kazuki Tawaratsumida, Vanessa Redecke, Ruiqiong Wu, Jeeba Kuriakose, Jill J. Bouchard, Tanja Mittag, Brian K. Lohman, Ashutosh Mishra, Anthony A. High, Hans Häcker
Publikováno v:
Science advances. 8(27)
Toll-like receptors (TLRs) recognize pathogen- and host-derived factors and control immune responses via the adaptor protein MyD88 and members of the interferon regulatory transcription factor (IRF) family. IRFs orchestrate key effector functions, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a7eb0e43d253d56740d8a3f0f27f49
https://pubmed.ncbi.nlm.nih.gov/35857476
https://pubmed.ncbi.nlm.nih.gov/35857476
Autor:
Peter Vogel, Cliff Guy, Heather Tillman, Patrick D. Walker, Hans Häcker, Jeeba Kuriakose, Sirish K. Ippagunta, Vanessa Redecke, Jingran Zhou, Ruiqiong Wu
Publikováno v:
Journal of Clinical Investigation. 129:2251-2265
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with genetic and environmental contributions. Hallmarks of the disease are the appearance of immune complexes (IC) containing autoreactive Abs and TLR-activating nucleic acids, whose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6813ba7f3c1227328c9501d191986dcc
https://doi.org/10.1172/jci125116
https://doi.org/10.1172/jci125116
Publikováno v:
Immunology. 148:216-226
SHARPIN is an essential component of the linear ubiquitin chain assembly complex (LUBAC) complex that controls signalling pathways of various receptors, including the tumour necrosis factor receptor (TNFR), Toll-like receptor (TLR) and antigen recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538a8cfb0540a8694a1f2109fb82eebf
https://doi.org/10.1111/imm.12604
https://doi.org/10.1111/imm.12604