Výsledky vyhledávání - "Jee Y. Chung"

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

Autor: Su Chang Lin, Hao Wu, Miao Lu, Jee Y. Chung, Betty Lamothe, Amy Y. Lam, Yu Chih Lo, Kanagalaghatta R. Rajashankar, Bryant G. Darnay

Publikováno v: Journal of Molecular Biology. 376:526-540

Nuclear factor kappaB (NF-kappaB) activation in tumor necrosis factor, interleukin-1, and Toll-like receptor pathways requires Lys63-linked nondegradative polyubiquitination. A20 is a specific feedback inhibitor of NF-kappaB activation in these pathw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92a75b74ffb8a7f6a84ce24b229acd1
https://doi.org/10.1016/j.jmb.2007.11.092

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All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

Autor: Hao Wu, Hong Ye, Young Chul Park, Jee Y. Chung

Publikováno v: Journal of Cell Science. 115:679-688

The tumor necrosis factor (TNF) receptor associated factors (TRAFs) have emerged as the major signal transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor (IL-1R/TLR) superfamily. TRAFs collectively play impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce2a1284a5db83ed3edb6afd803e8a1
https://doi.org/10.1242/jcs.115.4.679

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Tea and Tea Polyphenols in Cancer Prevention

Autor: Saranjit K. Chhabra, Jee Y. Chung, Mao Jung Lee, Guang Yu Yang, Chung S. Yang

Publikováno v: The Journal of Nutrition. 130:472S-478S

The inhibitory action of tea (Camellia sinensis) and tea components against cancer formation has been demonstrated in different animal models involving different organ sites in many laboratories. The possible preventive activity of tea against cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81abe83d9c89085f7d91099a45633a5
https://doi.org/10.1093/jn/130.2.472s

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Mechanisms of inhibition of the Ras‐MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (‐)‐epigallocatechin‐3‐gallate and theaflavin‐3,3′‐digallate 1

Autor: Jae O. Park, Zigang Dong, Chung S. Yang, Hnin Phyu, Jee Y. Chung

Publikováno v: The FASEB Journal. 15:2022-2024

Our previous study showed that tea polyphenols inhibited MAP kinase and AP-1 activities in mouse epidermal JB6 cells and the corresponding H-ras-transformed cell line 30.7b Ras 12. The present study investigated the mechanisms of this inhibition. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4c61a136abbd4b051aa135adef7d3c7
https://doi.org/10.1096/fj.01-0031fje

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High-Affinity Interaction between IKKβ and NEMO

Autor: Rebecca L. Rich, David G. Myszka, Upendra Maddineni, Jee Y. Chung, Yu Chih Lo, Hao Wu

The Ser/Thr-specific IkappaB kinase (IKK), which comprises IKKalpha or IKKbeta and the regulatory protein NEMO, is at the bottleneck for NF-kappaB activation. IKK activity relies on interaction between NEMO and IKKalpha or IKKbeta. A conserved region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c7355d0c0c548218ad6e59f0eb3a67
https://europepmc.org/articles/PMC3673718/

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Structural Revelations of TRAF2 Function in TNF Receptor Signaling Pathway

Autor: Miao Lu, Qian Yin, Hao Wu, Jee Y. Chung

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9780387706290

The tumor necrosis factor (TNF) receptor (TNFR) superfamily consists of over 20 type-I transmembrane proteins with conserved N-terminal cysteine-rich domains (CRDs) in the extracellular ligand binding region, which are specifically activated by the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84af48d853a45804f9305944a4df8eaf
https://doi.org/10.1007/978-0-387-70630-6_8

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Molecular Basis for the Unique Specificity of TRAF6

Autor: Su Chang Lin, Miao Lu, Qian Yin, Jee Y. Chung, Hao Wu

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9780387706290

Tumor necrosis factor (TNF) receptor (TNFR) associated factor 6 (TRAF6) is a unique member of the TRAF family of adaptor proteins that is involved in both the TNF receptor superfamily and the interleukin-1 receptor (IL-1R)/Toll-like receptor (TLR) su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9896434eaedfd4834a44c2f6a3c0e39d
https://doi.org/10.1007/978-0-387-70630-6_10

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Structural revelations of TRAF2 function in TNF receptor signaling pathway

Autor: Jee Y, Chung, Miao, Lu, Qian, Yin, Hao, Wu

Publikováno v: Advances in experimental medicine and biology. 597

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::484088735529a28fe8792edcaff40d22
https://pubmed.ncbi.nlm.nih.gov/17633020

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Molecular basis for the unique specificity of TRAF6

Autor: Jee Y, Chung, Miao, Lu, Qian, Yin, Su-Chang, Lin, Hao, Wu

Publikováno v: Advances in experimental medicine and biology. 597

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::40fd3cc728fd42f1838eb9a0b095684e
https://pubmed.ncbi.nlm.nih.gov/17633022

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TNF Receptor Associated Factors

Autor: Jee Y. Chung, Hong Ye, W U Hao, Young Chul Park

Publikováno v: Handbook of Cell Signaling

The TNF-receptor-associated factors (TRAFs), which currently consist of six members (TRAFl-6) in mammals, have emerged to be the major adapter proteins for these receptors. Through versatile protein-protein interactions,TRAFs link receptor activation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8af8d787c5e0e7b74950fe463d423a57
https://doi.org/10.1016/b978-012124546-7/50415-0

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