Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jee Wei E. Chen"'
Publikováno v:
Frontiers in Materials, Vol 5 (2018)
The extracellular matrix (ECM) is critical in tumor growth and invasive potential of cancer cells. In glioblastoma tumors, some components of the native brain ECM such as hyaluronic acid (HA) have been suggested as key regulators of processes associa
Externí odkaz:
https://doaj.org/article/cd4fdfd290a8469dbc2689d53373f93a
Autor:
Gabrielle L. Wolter, Jee Wei E. Chen, Jann N. Sarkaria, Sara Pedron, Sarah E. Laken, Brendan A.C. Harley
Publikováno v:
Biomaterials
Therapeutic options to treat primary glioblastoma (GBM) tumors are scarce. GBM tumors with epidermal growth factor receptor (EGFR) mutations, in particular a constitutively active EGFRvIII mutant, have extremely poor clinical outcomes. GBM tumors wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0773040b655bf6d1c43dd8b8bea6c686
https://doi.org/10.1101/556324
https://doi.org/10.1101/556324
Publikováno v:
Cancer Research. 77:931-931
Introduction Glioblastoma (GBM) is the most common and lethal form of brain cancer. Poor survival is linked to diffuse infiltration throughout the brain, suggesting the need to examine the effect of the tissue environment at the margins of the GBM tu