Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jed. M. Burns"'
Autor:
Tyler Fahrenhorst-Jones, David L. Marshall, Jed. M. Burns, Gregory K. Pierens, Robert E. Hormann, Allison M. Fisher, Paul V. Bernhardt, Stephen J. Blanksby, G. Paul Savage, Philip E. Eaton, Craig M. Williams
Publikováno v:
Chemical Science. 14:2821-2825
1-Azahomocubane has been prepared 56 years after the parent hydrocarbon. Introduction of a nitrogen atom into this constrained polycyclic environment resulted in minimal changes to the framework geometry, with s-character of the nitrogen lone pair in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5fc35dd6725ef4ebb7fbf3ef4c62ec
https://doi.org/10.1039/d3sc00001j
https://doi.org/10.1039/d3sc00001j
Autor:
James J. De Voss, G. Paul Savage, Maree T. Smith, Glen M. Boyle, Benjamin A. Chalmers, John Tsanaktsidis, Jeanette E. Stok, Vicky M. Avery, Paul V. Bernhardt, Hui Xing, Melissa Sykes, Craig M. Williams, Sevan D. Houston, Clementina Farfan Soto, Jed M. Burns, Tyler Fahrenhorst-Jones
Publikováno v:
Organic & Biomolecular Chemistry. 17:6790-6798
The cubane phenyl ring bioisostere paradigm was further explored in an extensive study covering a wide range of pharmaceutical and agrochemical templates, which included antibiotics (cefaclor, penicillin G) and antihistamine (diphenhydramine), a smoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b405b9f46fdced55075c7e77e78dae7
https://doi.org/10.1039/c9ob01238a
https://doi.org/10.1039/c9ob01238a
Autor:
Luke W. Guddat, Jed M. Burns, G. Paul Savage, Sharon Chow, Craig M. Williams, Nada H. Eisa, David M. Pinkerton, Timothy J. Vanden Berg, Ahmed Chadli, Kashish Kainth
Publikováno v:
Chemistry – A European Journal. 25:1451-1455
D-Ring-seco-limonoids (tetranortriterpenoids), such as gedunin and xylogranin B display anti-cancer activity, acting via inhibition of Hsp90 and/or associated chaperon machinery (e.g., p23). Despite this, these natural products have received relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0886f08539d8b6900bf065badd692ba8
https://doi.org/10.1002/chem.201805420
https://doi.org/10.1002/chem.201805420
Publikováno v:
The Journal of organic chemistry. 86(11)
The course of the Barton-Kellogg (BK) reaction for alkyl- and aryl-substituted substrates has been investigated at the DLPNO-CCSD(T)/def2-TZVPP//ωB97X-D/def2-TZVPP level of theory, with results compared to available experimental kinetic data. Throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8feb7021f918223e95ee79b5a66d9e
https://pubmed.ncbi.nlm.nih.gov/34015929
https://pubmed.ncbi.nlm.nih.gov/34015929
Publikováno v:
Journal of chemical information and modeling. 60(12)
Glycosaminoglycans (GAGs) are a family of anionic carbohydrates that play an essential role in the physiology and pathology of all eukaryotic life forms. Experimental determination of GAG-protein complexes is challenging due to their difficult isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb0b12e1993512c648bc81b97af343a
https://pubmed.ncbi.nlm.nih.gov/33152249
https://pubmed.ncbi.nlm.nih.gov/33152249
Glycosaminoglycans (GAGs) are a family of anionic carbohydrates that play an essential role in the physiology and pathology of all eukaryotic life. Experimental determination of GAG-protein complexes remains difficult due to the considerable diversit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8155e441f3fec81ea900751237f9dd
https://doi.org/10.26434/chemrxiv.12279251.v1
https://doi.org/10.26434/chemrxiv.12279251.v1
Publikováno v:
European Journal of Organic Chemistry. 2019:303-308
The Ley–Griffith oxidation, which is catalyzed by tetra-n-propylammonium perruthenate (TPAP, nPrN[RuO]), is a popular method for not only controlled oxidation of primary alcohols to aldehydes, but also a host of other synthetically useful transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e9807126b6b11f78d8670a409faffb3
https://doi.org/10.1002/ejoc.201800860
https://doi.org/10.1002/ejoc.201800860
Publikováno v:
Synthesis. 50:1750-1772
The Claisen rearrangement of benzylic substrates (benzyl vinyl ethers) has received considerably less attention than its well-known aliphatic and normal aromatic variants. Here, we review the rearrangement of both benzylic and heterobenzylic substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e1d2366597827c98a367988187124a
https://doi.org/10.1055/s-0036-1589529
https://doi.org/10.1055/s-0036-1589529
Autor:
Jack K. Clegg, Jed M. Burns, Craig M. Williams, Tyler Fahrenhorst-Jones, C. N. R. Rao, Hydar A. AL-Fayaad, Kasun S. Athukorala Arachchige, J. N. Behera
Publikováno v:
Chemical Communications. 55:11751-11753
All 21 [n]-azacubanes are proposed by theoreticians to be stable, however, to-date only the synthesis of 1,4-diazacubane has been reported - as a Ni2+ templated Kagome metal organic framework (MOF). Described herein is the structural reassignment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0688ca120f162991231fc21010eda3
https://doi.org/10.1039/c9cc06272f
https://doi.org/10.1039/c9cc06272f
Publikováno v:
European Journal of Organic Chemistry. 2017:252-256
Claisen rearrangements of benzyl vinyl ethers are much less facile than those of aliphatic allyl vinyl ethers, and their synthetic utility has remained relatively unexplored. A one-pot procedure is reported for the generation and Claisen rearrangemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4b1ce5e2cb21f454902b1bc043f55b
https://doi.org/10.1002/ejoc.201601354
https://doi.org/10.1002/ejoc.201601354