Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jed J. Lye"'
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Challenges in diagnosing primary immunodeficiency are numerous and diverse, with current whole-exome and whole-genome sequencing approaches only able to reach a molecular diagnosis in 25–60% of cases. We assess these problems and discuss how RNA-fo
Externí odkaz:
https://doaj.org/article/085a2e7e20d944c5997f50030f7e736f
Autor:
Nicholas J. Gutowski, Eva Latorre, Janet E. Holley, Jed J. Lye, Ben P. Lee, Lorna W. Harries, Stefania Bandinelli, Luigi Ferrucci
Publikováno v:
GeroScience. 41:561-573
The accumulation of senescent cells in tissues is causally linked to the development of several age-related diseases; the removal of senescent glial cells in animal models prevents Tau accumulation and cognitive decline. Senescent cells can arise thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f215946e0ccc35a08e041af28dec2c18
https://doi.org/10.1007/s11357-019-00100-3
https://doi.org/10.1007/s11357-019-00100-3
Autor:
Jed J, Lye, Eva, Latorre, Ben P, Lee, Stefania, Bandinelli, Janet E, Holley, Nicholas J, Gutowski, Luigi, Ferrucci, Lorna W, Harries
Publikováno v:
GeroScience
The accumulation of senescent cells in tissues is causally linked to the development of several age-related diseases; the removal of senescent glial cells in animal models prevents Tau accumulation and cognitive decline. Senescent cells can arise thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fcf8706579737c4993d3eaadfdcfcdfb
https://pubmed.ncbi.nlm.nih.gov/31654269
https://pubmed.ncbi.nlm.nih.gov/31654269
Autor:
Wai HA; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lord J; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lyon M; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Gunning A; Exeter Genomics Laboratory, Royal Devon & Exeter NHS Foundation Trust, Exeter, UK., Kelly H; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Cibin P; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Seaby EG; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Translational Genomics Unit, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Spiers-Fitzgerald K; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lye J; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Ellard S; Exeter Genomics Laboratory, Royal Devon & Exeter NHS Foundation Trust, Exeter, UK., Thomas NS; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Bunyan DJ; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Douglas AGL; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Clinical Genetics Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Baralle D; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK. d.baralle@soton.ac.uk.; Wessex Clinical Genetics Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK. d.baralle@soton.ac.uk.
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2020 Jun; Vol. 22 (6), pp. 1129.
Autor:
Wai HA; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lord J; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lyon M; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Gunning A; Exeter Genomics Laboratory, Royal Devon & Exeter NHS Foundation Trust, Exeter, UK., Kelly H; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Cibin P; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Seaby EG; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Translational Genomics Unit, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Spiers-Fitzgerald K; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Lye J; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Ellard S; Exeter Genomics Laboratory, Royal Devon & Exeter NHS Foundation Trust, Exeter, UK., Thomas NS; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Bunyan DJ; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, UK., Douglas AGL; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Wessex Clinical Genetics Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Baralle D; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK. d.baralle@soton.ac.uk.; Wessex Clinical Genetics Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK. d.baralle@soton.ac.uk.
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2020 Jun; Vol. 22 (6), pp. 1005-1014. Date of Electronic Publication: 2020 Mar 03.