Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jed Dean"'
Autor:
Jim Vallandingham, Harmen M. van Rossum, Kedar G. Patel, Shawn Szyjka, Zach Serber, Jed Dean, R. Cameron Coates, Stephen Blaskowski
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 46:187-201
This study details a reliable and efficient method for CRISPR–Cas9 genome engineering in the high amino acid-producing strain of Corynebacterium glutamicum, NRRL-B11474. Our investigation demonstrates that a plasmid-encoded single-guide RNA paired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c282b32afcf08b0896929e498b5b61f
https://doi.org/10.1007/s10295-018-2112-7
https://doi.org/10.1007/s10295-018-2112-7
Autor:
Max G. Schubert, Erin H. Wilson, Brian L. Hawthorne, James W. Weis, Christopher D. Reeves, Michael Bissell, Shiori Sagawa, Jed Dean, Darren Platt
Publikováno v:
ACS Synthetic Biology. 5:471-478
We describe here the Genotype Specification Language (GSL), a language that facilitates the rapid design of large and complex DNA constructs used to engineer genomes. The GSL compiler implements a high-level language based on traditional genetic nota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2aff39a50f5e4ca110db0ccb38e2d7
https://doi.org/10.1021/acssynbio.5b00194
https://doi.org/10.1021/acssynbio.5b00194
Autor:
Sunil S. Chandran, Kedar G. Patel, Stefan de Kok, Jack D. Newman, Zach Serber, Leslie H. Stanton, Darren Platt, Victor Holmes, Maxime Durot, Todd Slaby, Jed Dean, Elaine B. Shapland
Publikováno v:
ACS synthetic biology. 3(2)
Assembly of DNA parts into DNA constructs is a foundational technology in the emerging field of synthetic biology. An efficient DNA assembly method is particularly important for high-throughput, automated DNA assembly in biofabrication facilities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba27db5a8c2da294e8cab90c025451d2
https://pubmed.ncbi.nlm.nih.gov/24932563
https://pubmed.ncbi.nlm.nih.gov/24932563
Autor:
Yossef Ben-Harosh, Eugenio Mancera, Erez Braun, Michelle Nguyen, Jed Dean, Elad Stolovicki, Lior David, Lars M. Steinmetz, Lindsay Moore, Raquel Tamse
Publikováno v:
Molecular biology and evolution. 30(7)
Frequently during evolution, new phenotypes evolved due to novelty in gene regulation, such as that caused by genome rewiring. This has been demonstrated by comparing common regulatory sequences among species and by identifying single regulatory muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f663ea27ab2af258d9b829afc48b92d
https://pubmed.ncbi.nlm.nih.gov/23589456
https://pubmed.ncbi.nlm.nih.gov/23589456
Autor:
Himanshu Sinha, Ronald W. Davis, Jed Dean, Sujatha Krishnakumar, John H. McCusker, Michelle Nguyen, Sandra Clauder-Münster, Getao Shi, Peter J. Oefner, Renata C. Pascon, Lior David, Lars M. Steinmetz
Publikováno v:
Genetics. 180(3)
Several quantitative trait loci (QTL) mapping strategies can successfully identify major-effect loci, but often have poor success detecting loci with minor effects, potentially due to the confounding effects of major loci, epistasis, and limited samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b94665d9ddc0a7e35825c2b405614d
https://pubmed.ncbi.nlm.nih.gov/18780730
https://pubmed.ncbi.nlm.nih.gov/18780730
Autor:
Nicole Klinkner, Todd Slaby, Sunil S. Chandran, Elaine B. Shapland, Daniel Hollis, Kedar G. Patel, Yandi Dharmadi, Jed Dean
Publikováno v:
Nucleic Acids Research
DNA ‘assembly’ from ‘building blocks’ remains a cornerstone in synthetic biology, whether it be for gene synthesis (∼1 kb), pathway engineering (∼10 kb) or synthetic genomes (>100 kb). Despite numerous advances in the techniques used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6ca4877314e04c72fd3252e9c11646
https://doi.org/10.1093/nar/gkt1088
https://doi.org/10.1093/nar/gkt1088