Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jebecka Hudak"'
Publikováno v:
Cell Transplantation, Vol 16 (2007)
Delivery of neurotrophic molecules to the brain has potential for preventing neuronal loss in neurodegenerative disorders. Choroid plexus (CP) epithelial cells secrete numerous neurotrophic factors, and encapsulated CP transplants are neuroprotective
Externí odkaz:
https://doaj.org/article/ac39d00d3eae4a898bb6e9db9896755d
Publikováno v:
Cell Transplantation, Vol 16 (2007)
Delivery of neurotrophic molecules to the CNS is a potential treatment for preventing the neuronal loss in neurological disorders such as Huntington's disease (HD). Choroid plexus (CP) epithelial cell transplants secrete several neurotrophic factors
Externí odkaz:
https://doaj.org/article/bcd04b6b743f41e29f644fb26e548d9f
Autor:
Jebecka Hudak, William J. Bell, Dwaine F. Emerich, Omar Abdel-Rahman Ali, Edward J. Doherty, David J. Mooney, Marie-Therese Laliberte, Tracie Fradet
Publikováno v:
Journal of Controlled Release. 154:249-257
We previously engineered a macroporous, polymer-based vaccine that initially produces GM-CSF gradients to recruit local dendritic cells and subsequently presents CpG oligonucleotides, and tumor lysate to cell infiltrates to induce immune cell activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b37c43cd46d8fcc7b9d98fc15f1a05c
https://doi.org/10.1016/j.jconrel.2011.06.021
https://doi.org/10.1016/j.jconrel.2011.06.021
Publikováno v:
Cell Transplantation, Vol 16 (2007)
Delivery of neurotrophic molecules to the CNS is a potential treatment for preventing the neuronal loss in neurological disorders such as Huntington's disease (HD). Choroid plexus (CP) epithelial cell transplants secrete several neurotrophic factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1968072392748d87de4ad81de8565e
https://doi.org/10.3727/000000007783464867
https://doi.org/10.3727/000000007783464867
Autor:
Roger H. Pak, Louis Grenier, Julian Adams, Jeffrey K. Tong, James D. Wright, Janid A. Ali, Courtney Penders, Emmanuel Normant, Jens R. Sydor, Jon S. Patterson, Melissa Pink, Jie Ge, Jebecka Hudak, Marlene Dembski, Yilong Zhang, Jim Sang, Christine S. Pien, Caroline N. Woodward, James R. Porter, Margaret Read, John A. Barrett, David Grayzel, Vito J. Palombella
Publikováno v:
Proceedings of the National Academy of Sciences. 103:17408-17413
Heat shock protein 90 (Hsp90) is an emerging therapeutic target of interest for the treatment of cancer. Its role in protein homeostasis and the selective chaperoning of key signaling proteins in cancer survival and proliferation pathways has made it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f11c8483df52f90a7ab65229a46a8d6
https://doi.org/10.1073/pnas.0608372103
https://doi.org/10.1073/pnas.0608372103
Autor:
Omar Abdel-Rahman Ali, William J. Bell, Ed Doherty, Jebecka Hudak, Dwaine F. Emerich, David J. Mooney, Marie-Therese Laliberte, Tracie Fradet
Publikováno v:
Pharmaceutical research. 28(5)
The prognosis for glioma patients is poor, and development of new treatments is critical. Previously, we engineered polymer-based vaccines that control GM-CSF, CpG-oligonucleotide, and tumor-lysate presentation to regulate immune cell trafficking and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fa4e916ccc3636f7cedc0b2203c9ee
https://pubmed.ncbi.nlm.nih.gov/21225320
https://pubmed.ncbi.nlm.nih.gov/21225320
Publikováno v:
Proteins. 69(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2b59817561c1fb707dbdd883c76074
https://pubmed.ncbi.nlm.nih.gov/17600833
https://pubmed.ncbi.nlm.nih.gov/17600833
Autor:
Roderick V. Jensen, Dwaine F. Emerich, Patricia Schneider, Briannan Bintz, Jebecka Hudak, William J. Bell, Bronwyn H. Bryant, Chris Thanos
Publikováno v:
Tissue engineering. 13(4)
The choroid plexus (CP) is a transplantable cell source secreting tropic and trophic factors for the treatment of brain and peripheral trauma characterized by cellular loss or dysfunction. Here we characterize the expression and secretion of vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ecd80e75400e9133d176ec6998d6fb
https://pubmed.ncbi.nlm.nih.gov/17432950
https://pubmed.ncbi.nlm.nih.gov/17432950
Autor:
Matthew S. Kelker, Jebecka Hudak, Wolfgang Peti, and Angus C. Nairn, Barbara Dancheck, Rene P. Kessler, Tingting Ju
Publikováno v:
Biochemistry. 46(9)
Neurabin and spinophilin are neuronal scaffolding proteins that play important roles in the regulation of synaptic transmission through their ability to target protein phosphatase 1 (PP1) to dendritic spines where PP1 dephosphorylates and inactivates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b05de9409e78d63bc50918c691a462e
https://pubmed.ncbi.nlm.nih.gov/17279777
https://pubmed.ncbi.nlm.nih.gov/17279777
Autor:
Jon Patterson, Vito J. Palombella, James H. Porter, David Grayzel, Asimina T. Georges, John P. Barrett, Christine Pien, Adams Julian, Jennie Ge, Jeffrey K. Tong, Kenneth C. Anderson, Kerry Spear, Roger H. Pak, Janid Ali, Jebecka Hudak, Constantine S. Mitsiades, Emmanuel Normant, James Homer Wright, Melissa Pink, Louis Grenier, Jens Sydor, Michael Foley, Yun Gao, Junbiao Sang
Publikováno v:
Blood. 104:4922-4922
IPI-504 is a novel inhibitor of Hsp90 based on the geldanamycin pharmacophore. When placed in rat, monkey, and human blood, IPI-504 rapidly converts to the known and well-studied compound 17-allylamino-17-demethoxy-geldanamycin (17-AAG). 17-AAG is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd62aefb41f6324e4b5334429ce29775
https://doi.org/10.1182/blood.v104.11.4922.4922
https://doi.org/10.1182/blood.v104.11.4922.4922