Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jeannine R. Larocque"'
Autor:
Elizabeth L. Graham, Joel Fernandez, Shagun Gandhi, Iqra Choudhry, Natalia Kellam, Jeannine R. LaRocque
Publikováno v:
PLoS Genetics, Vol 20, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/832ab8100d94437fb6fb10095dfb33af
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3773-3780 (2019)
DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous
Externí odkaz:
https://doaj.org/article/946cc2c36a24469cbc2ef0010ceec2de
Autor:
Jon-Philippe K. Hyatt, Lisa eNguyen, Allison E. Hall, Ashley M. Huber, Jessica C. Kocan, Julie A. Mattison, Rafael ede Cabo, Jeannine R. Larocque, Robert J. Talmadge
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Shifts in myosin heavy chain (MHC) expression within skeletal muscle can be induced by a host of stimuli including, but not limited to, physical activity, alterations in neural activity, aging, and diet or obesity. Here, we hypothesized that both age
Externí odkaz:
https://doaj.org/article/b9d33b8a4180426aa1f0a57e40ab272b
Publikováno v:
Genes
Volume 12
Issue 9
Genes, Vol 12, Iss 1430, p 1430 (2021)
Volume 12
Issue 9
Genes, Vol 12, Iss 1430, p 1430 (2021)
DNA double-strand breaks (DSBs) are a particularly genotoxic type of DNA damage that can result in chromosomal aberrations. Thus, proper repair of DSBs is essential to maintaining genome integrity. DSBs can be repaired by non-homologous end joining (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29469f9e9fb2acc1cb5612fadc0a24e8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3773-3780 (2019)
DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4957f6d7bf002c6c86b9f600b81c66fb
https://doi.org/10.1534/g3.119.400607
https://doi.org/10.1534/g3.119.400607
Autor:
Nicholas Barnaba, Jeannine R. LaRocque
Publikováno v:
Cell Cycle
Disruption of cell cycle checkpoints has been well established as a hallmark of cancer. In particular, the G1-S transition mediated by the cyclin D-cyclin-dependent kinase 4/6 (CDK4/6) pathway is dysregulated in more than 90% of melanoma cases. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ed898675f02adb20c042350e47d04c
https://pubmed.ncbi.nlm.nih.gov/33966611
https://pubmed.ncbi.nlm.nih.gov/33966611
Autor:
Jeannine R. LaRocque, Irene Chiolo, Carolyn M. Hofley, Elisa Jayne Bienenstock, Laetitia Delabaere, Faraz Sohail, Hans Sebastian, Henry A. Ertl, Dashiell J Massey
Publikováno v:
Aging Cell
Summary Aging is characterized by genome instability, which contributes to cancer formation and cell lethality leading to organismal decline. The high levels of DNA double‐strand breaks (DSBs) observed in old cells and premature aging syndromes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af422f9fc517c2731721ca753715eb4
https://doi.org/10.1111/acel.12556
https://doi.org/10.1111/acel.12556
Autor:
Madison Betcher, Pallavi Tatapudy, Rebecca L. Cox, Jeannine R. LaRocque, Romil K. Patel, Yaron Dayani, Carolyn M. Hofley
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
RecQ helicases are a family of proteins involved in maintaining genome integrity with functions in DNA repair, recombination, and replication. The human RecQ helicase family consists of five helicases: BLM, WRN, RECQL, RECQL4, and RECQL5. Inherited m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba28b49fc845f6f0fc22e9d9424963e7
https://doi.org/10.1038/s41598-019-54101-5
https://doi.org/10.1038/s41598-019-54101-5
Autor:
Keli Agama, Yves Pommier, Ronit I. Yarden, Jennifer Lapier, Hinanit Koltai, Christopher Albanese, Michael P. Croglio, Lucas Tricoli, Victor S. Wang, Jeannine R. LaRocque, Cristina Prandi, Colin P. Ryan, Emma Artuso, Jamie P. Schlarbaum, Yu Chen, Yaron Dayani, Jefferson M. Haake
Publikováno v:
Oncotarget
Strigolactones are a novel class of plant hormones produced in roots that regulate shoot and root development. We previously reported that strigolactone analogs (SLs) induce G2/M cell cycle arrest and apoptosis in a variety of human cancer cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995449c3db7f0e1e2813c187d6c9d088
https://doi.org/10.18632/oncotarget.7414
https://doi.org/10.18632/oncotarget.7414
Publikováno v:
The Journal of the American Board of Family Medicine. 28:759-766
Introduction: The general public’s preferences for modes of communication (other than in-person communication) for medical test results were investigated. We hypothesized that patients would prefer a variety of methods to receive common tests resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca873d856a08f65532136b3640a5a61a
https://doi.org/10.3122/jabfm.2015.06.150030
https://doi.org/10.3122/jabfm.2015.06.150030