Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeannine M. Hollis"'
Autor:
Rui-Qin Liu, Timothy Burn, Kathleen Murphy, Gregory Hollis, Stuart A. Rosenfeld, Barbara H. Wiswall, Robert A. Copeland, Yoshifumi Itoh, Carl P. Decicco, Hideaki Nagase, F. Yang, Robert C. Bruckner, Robert C. Newton, James M. Trzaskos, Henry J. George, Richard Wynn, J. L. Duke, Ronald L. Magolda, Dawn Ellis, Michael A. Pratta, A. Rockwell, Ilgar Abbaszade, E. C. Arner, Harold D. Ross, M.C. Hillman, Micky D. Tortorella, Kimberly A. Solomon, Jeannine M. Hollis
Publikováno v:
Science. 284:1664-1666
We purified, cloned, and expressed aggrecanase, a protease that is thought to be responsible for the degradation of cartilage aggrecan in arthritic diseases. Aggrecanase-1 [a disintegrin and metalloproteinase with thrombospondin motifs–4 (ADAMTS-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc2a5018fca3fd44f5c1740c2430b66
https://doi.org/10.1126/science.284.5420.1664
https://doi.org/10.1126/science.284.5420.1664
Autor:
Siew Peng Ho, Paul A. Friedman, Richard J. Focht, Joseph E. Dinchuk, Nancy L. Henderson, Timothy Burn, Jeannine M. Hollis, Reid Huber, Karyn T. O'Neil, John Link, Gregory Hollis, Michael Scully
Publikováno v:
The Journal of biological chemistry. 275(50)
The mouse aspartyl beta-hydroxylase gene (Asph, BAH) has been cloned and characterized. The mouse BAH gene spans 200 kilobase pairs of genomic DNA and contains 24 exons. Of three major BAH-related transcripts, the two largest (6,629 and 4,419 base pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d43f4af65d649760c742510b9e2e47
https://pubmed.ncbi.nlm.nih.gov/10956665
https://pubmed.ncbi.nlm.nih.gov/10956665
Autor:
Carl P. Decicco, M.C. Hillman, Dawn Ellis, Henry J. George, Ronald L. Magolda, Rui-Qin Liu, O. Harold Ross, John Link, Micky D. Tortorella, James M. Trzaskos, J. L. Duke, Jeannine M. Hollis, Gregory Hollis, Michael A. Pratta, Robert C. Bruckner, Fude Yang, Stuart A. Rosenfeld, Timothy Burn, Robert A. Copeland, Elizabeth C. Arner, Hideaki Nagase, Richard Wynn, Yoshifumi Itoh, Barbara H. Wiswall, Ilgar Abbaszade, Kathleen Murphy, Robert C. Newton
Publikováno v:
The Journal of biological chemistry. 274(33)
Aggrecan is responsible for the mechanical properties of cartilage. One of the earliest changes observed in arthritis is the depletion of cartilage aggrecan due to increased proteolytic cleavage within the interglobular domain. Two major sites of cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c4757a6c4973854ee5e31d6c868316
https://pubmed.ncbi.nlm.nih.gov/10438522
https://pubmed.ncbi.nlm.nih.gov/10438522