Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeannine Delaney"'
Autor:
Jen-Chieh Tseng, Nara Narayanan, Guojie Ho, Kevin Groves, Jeannine Delaney, Bagna Bao, Jun Zhang, Jeffrey Morin, Sylvie Kossodo, Milind Rajopadhye, Jeffrey D Peterson
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models. However, it is relatively insensitive, and often requires long treatment courses to achieve gr
Externí odkaz:
https://doaj.org/article/004dc262c9164482acf31b352bed2c16
Autor:
Jeannine Delaney, Bagna Bao, Jeffrey D. Peterson, Guojie Ho, Milind Rajopadhye, Jun Zhang, Kristine O. Vasquez
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:288-298
In mouse pharmacokinetic (PK) studies, current standard methods often require large numbers of animals to support collection of blood samples serially over a defined time range. We have developed and validated a non-invasive fluorescence molecular to
Autor:
Jun Zhang, Milind Rajopadhye, Nara Narayanan, Jeannine Delaney, Kevin Groves, Bagna Bao, Guojie Ho, Jeffrey D. Peterson, Jen-Chieh Tseng, Sylvie Kossodo, Jeffrey Morin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models. However, it is relatively insensitive, and often requires long treatment courses to achieve gr
Autor:
Miller Stephan S, Zhifang Li, Alan Rapoza, Darren P. Baker, Matthew Betzenhauser, Jeannine Delaney, Caroline Coots, Dingyi Wen, Azita Kaffashan, Bruno Domon, Raymond E. Boynton, Ling Ling Chen, Alan Gill, Carmen N. Young, Nelly Viseux, Liqing Chen, Konrad Miatkowski, Hess Donna M, Paula S. Hochman, Robert S. Gronke, Robert M. Arduini, R. Blake Pepinsky
Publikováno v:
Protein Expression and Purification. 34:229-242
To identify potential new clinical uses and routes of administration for human interferon-beta-1a (IFN-beta-1a), we have developed an expression and purification procedure for the preparation of highly purified rat interferon-beta (IFN-beta) suitable
Publikováno v:
Rapid Communications in Mass Spectrometry. 16:192-200
The increasing interest in the development of glycoproteins for therapeutic purposes has created a greater demand for methods to characterize the sugar moieties bound to them. Traditionally, released carbohydrates are derivatized using such methods a
Autor:
Paul Vouros, Jeannine Delaney
Publikováno v:
Rapid Communications in Mass Spectrometry. 15:325-334
Reversed phase liquid chromatography was combined with the multiple stage mass analysis capability of an ion trap mass spectrometer for the characterization of permethylated oligosaccharide mixtures. The new method was used to separate the components
Autor:
Milind Rajopadhye, Jeffrey Morin, Garry Cuneo, Jeffrey D. Peterson, Guojie Ho, Wael Yared, Jeannine Delaney, Sylvie Kossodo
Publikováno v:
Journal of biomedical optics. 18(10)
Assays for blood levels of prostate-specific antigen (PSA), performed in prostate cancer detection, measure mostly inactive/complexed PSA and do not provide information regarding enzymatically active PSA, which is biologically more relevant. Thus, we
Autor:
Bagna Bao, David Z. Gao, Milind Rajopadhye, Dan McKay, Wael Yared, Jeannine Delaney, Bohumil Bednar, Daigen Xu, Karen N. Madden, Michael Klimas, Jun Zhang, Dorin V. Preda, Jeffrey D. Peterson, Jeff Morin, Kristine O. Vasquez, Cyrille Sur, M. David Percival
The renin-angiotensin system (RAS) is well studied for its regulation of blood pressure and fluid homeostasis, as well as for increased activity associated with a variety of diseases and conditions, including cardiovascular disease, diabetes, and kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a536dda813f955841db1f1beefa6cc04
https://europepmc.org/articles/PMC3423114/
https://europepmc.org/articles/PMC3423114/
Autor:
Sylvie Kossodo, Emma Handy, Jeff Morin, Garry Cuneo, Milind Rajopadhye, Jeannine Delaney, Jeffrey D. Peterson, Kevin Groves, Jun Zhang, Wael Yared
Publikováno v:
International Journal of Molecular Imaging
We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular tomographic imaging, allowed us to detect and quantify neutrophil elastase activityin vivo, in real time, and noninvasiv
Autor:
Zhendong Zhu, Helen Shi, Gwen Fate, Linning Yu, Billie J. Kline, Michael P. Pollastri, Wing Lam, Kathleen A. Farley, Francoise Berlioz, Cyrille Kuhn, Jeannine Delaney, Gregory S. Walker, Marc Bazin
Publikováno v:
Chemical biologydrug design. 70(4)
Major metabolites of dimethylaminoantipyrine have been synthesized using iron ortho-nitrophenylporphyrin chloride as biomimetic catalyst. Reactivity of iron tetrakis-ortho-nitrophenylporphyrin chloride [Fe(TNO2PP)Cl] has been compared with iron tetra