Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeannie Polihronis"'
Publikováno v:
Nuclear Medicine and Biology. 22:77-86
Streptavidin was conjugated to the second-generation TAG-72 monoclonal antibody CC49 at lysine amino acids, oxidized carbohydrates or reduced disulfides on the immunoglobulin. The streptavidin immunoconjugates were radiolabelled with 111In-DTPA-biocy
Publikováno v:
Nuclear medicine and biology. 23(4)
Pretargeted tumour imaging was performed in nude mice bearing subcutaneous LS174T human colon cancer xenografts with streptavidin-CC49 monoclonal antibody and 111In-DTPA-biocytin. Mice were administered 250 micrograms of streptavidin-CC49, followed 6
Autor:
Beverly J. Schmocker, Hartley Stern, Robert D. Odze, Jeannie Polihronis, Sylvain Houle, Jake J. Thiessen, Joel A. Kirsh, Manzur T. Damani, Kazy Hay, Steven Gallinger, Raymond M. Reilly
Publikováno v:
Nuclear medicine and biology. 20(1)
Sixteen patients with colorectal cancer were administered 37–74 MBq (1 mg) of radioiodinated B72.3 monoclonal antibody. Pharmacokinetic analysis was carried out on plasma and urine samples. Elimination from the plasma was biexponential with a mean
Publikováno v:
Nuclear medicine communications. 13(9)
The thin layer chromatographic (TLC) method for determining the radiochemical purity of 99Tcm-sestamibi suggested by the manufacturer of the kit is slow and inconvenient. In this study a more rapid reversed phase chromatography (Sep-Pak) technique is
Autor:
K. Ng, Raymond M. Reilly, Baruch Shpitz, Hartley Stern, Joel C. Kirsh, Steven Gallinger, Jeannie Polihronis, W. M. Ngai
Publikováno v:
Nuclear Medicine Communications. 15:379-387-387
Monoclonal antibody CC83 is a second-generation high-affinity antibody directed against the TAG-72 antigen in colorectal cancer. Our objectives were to evaluate the biodistribution, pharmacokinetics and imaging properties of CC83 labelled with 99Tcm
Autor:
K. Ng, M. T. Damani, W. M. Ngai, S. Houle, J. Kirsh, Hartley Stern, Jeannie Polihronis, Baruch Shpitz, Steven Gallinger, Raymond M. Reilly
Publikováno v:
Journal of Immunotherapy. 13:70