Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jeannette M, Dowell"'
Autor:
James E. Herndon, Sith Sathornsumetee, James J. Vredenburgh, Jennifer A. Quinn, Annick Desjardins, David A. Reardon, Darell D. Bigner, Sridharan Gururangan, Jeannette M. Dowell, Henry S. Friedman, Melissa Wagner, Allan H. Friedman, Jeremy N. Rich
Publikováno v:
Clinical Cancer Research. 13:1253-1259
Purpose: Recurrent grade III-IV gliomas have a dismal prognosis with minimal improvements in survival seen following currently available salvage therapy. This study was conducted to determine if the combination of a novel antiangiogenic therapy, beva
Autor:
James E. Herndon, David A. Reardon, Darell D. Bigner, Gregory J. Riggins, Chien-Tsun Kuan, Michael W. Graner, Jeannette M. Dowell, Carol J. Wikstrand, Kenji Wakiya
Publikováno v:
Clinical Cancer Research. 12:1970-1982
Purpose: More brain tumor markers are required for prognosis and targeted therapy. We have identified and validated promising molecular therapeutic glioblastoma multiforme (GBM) targets: human transmembrane glycoprotein nonmetastatic melanoma protein
Autor:
Mark Redston, Jeannette M. Dowell, Robert J. Mayer, James M. Fleshman, Carolyn C. Compton, Monica M. Bertagnolli, Scott D. Jewell, Brent W. Miedema, Jiri Bem, Donna Niedzwiecki
Publikováno v:
Journal of Clinical Oncology. 24:878-883
Purpose To determine whether sentinel lymph node (LN) sampling (SLNS) could reduce the number of nodes required to characterize micrometastatic disease (MMD) in patients with potentially curable colon cancer. Patients and Methods Cancer and Leukemia
Autor:
James J. Vredenburgh, John H. Sampson, Sridharan Gururangan, Annick Desjardins, Roger E. McLendon, James M. Provenzale, David A. Reardon, Alan Swaisland, Allan H. Friedman, James E. Herndon, Jeremy N. Rich, Sith Sathornsumetee, Jeannette M. Dowell, Jennifer A. Quinn, Sandy Tourt-Uhlig, Robert Smith, Judith S. Ochs, Peggy Lyons, Darell D. Bigner, Henry S. Friedman
Publikováno v:
Clinical Cancer Research. 12:860-868
Purpose: To determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of gefitinib, a receptor tyrosine kinase inhibitor of the epidermal growth factor receptor, plus sirolimus, an inhibitor of the mammalian target of rapamycin, amo
Autor:
David A, Reardon, Merrill J, Egorin, Jennifer A, Quinn, Jeremy N, Rich, Sridharan, Gururangan, Idharan, Gururangan, James J, Vredenburgh, Annick, Desjardins, Sith, Sathornsumetee, James M, Provenzale, James E, Herndon, Jeannette M, Dowell, Michael A, Badruddoja, Roger E, McLendon, Theodore F, Lagattuta, Kimberly P, Kicielinski, Gregor, Dresemann, John H, Sampson, Allan H, Friedman, August J, Salvado, Henry S, Friedman
Publikováno v:
Journal of Clinical Oncology. 23:9359-9368
Purpose We performed a phase II study to evaluate the combination of imatinib mesylate, an adenosine triphosphate mimetic, tyrosine kinase inhibitor, plus hydroxyurea, a ribonucleotide reductase inhibitor, in patients with recurrent glioblastoma mult
Autor:
James W. Fleshman, Brent W. Miedema, Jeannette M. Dowell, Robert J. Mayer, Mark Redston, Monica M. Bertagnolli, Carolyn C. Compton, Michael J. Zinner, Jiri Bem, Donna Niedzwiecki
Publikováno v:
Annals of Surgery. 240:624-630
Objective and Summary Background Data: Sentinel lymph node (LN) sampling, a technique widely used to manage breast cancer and melanoma, seeks to select LNs that accurately predict regional node status and can be extensively examined to identify nodal
Autor:
Linda Wasserman, Christian N. Arnold, C. Richard Boland, Jeannette M. Dowell, Monica M. Bertagnolli, Ajay Goel, Donna Niedzwiecki, Carolyn C. Compton, Robert J. Mayer
Publikováno v:
Cancer Biology & Therapy. 3:960-964
Introduction: Germ-line mutations of the APC gene are associated with familial adenomatous polyposis, and somatic mutations occur frequently in sporadic colorectal cancer. However, to abrogate APC function, both alleles must be inactivated. Recently,
Autor:
Deborah H. Allen, Amy Walker, Jeremy N. Rich, Sandra Tourt-Uhlig, Cindy Bohlin, Allan H. Friedman, John H. Sampson, Susanne Jackson, Mary Lou Affronti, Sridharan Gururangan, Karen Ziegler, James M. Provenzale, Jennifer A. Quinn, Michael A. Badruddoja, James E. Herndon, James J. Vredenburgh, Darrell D. Bigner, David A. Reardon, Steven Silverman, Henry S. Friedman, Jeannette M. Dowell
Publikováno v:
Neuro-Oncology. 6:134-144
In preclinical studies, BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea, plus CPT-11 (irinotecan) exhibits schedule-dependent, synergistic activity against malignant glioma (MG). We previously established the maximum tolerated dose of CPT-11 when admin
Autor:
Brian K. Auge, David F. Paulson, Ari D. Silverstein, Alon Z. Weizer, Philipp Dahm, Jeannette M. Dowell
Publikováno v:
Urology. 63:746-750
To perform a detailed comparison of the in-house hospital costs of patients undergoing radical perineal prostatectomy (RPP) and radical retropubic prostatectomy (RRP) performed with or without bilateral staging lymph node dissection (BPLND) for local
Autor:
Carol J. Wikstrand, Henry S. Friedman, Terry S. Peery, Jennifer A. Quinn, Sandra Tourt-Uhlig, Janet Dancey, Lauren B. Van Duyn, Roger E. McLendon, James C. Kao, Allan H. Friedman, James J. Vredenburgh, Kara Penne, Darell D. Bigner, James E. Herndon, Timothy T. Stenzel, Jeremy N. Rich, David A. Reardon, John H. Sampson, Jeannette M. Dowell, B.K. Ahmed Rasheed
Publikováno v:
Journal of Clinical Oncology. 22:133-142
Purpose To evaluate the efficacy and tolerability of gefitinib (ZD1839, Iressa; AstraZeneca, Wilmington, DE), a novel epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. Patients and Methods This was a