Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jeannette Adu-Bobie"'
Autor:
Barbara Capecchi, Paolo Montanari, Davide Serruto, Beatrice Aricò, Jeannette Adu-Bobie, Mariagrazia Pizza, Maria Scarselli, Daniele Veggi, Rino Rappuoli
Publikováno v:
Molecular Microbiology. 61:631-644
Summary NhhA, Neisseriahia/hsf homologue, or GNA0992, is an oligomeric outer membrane protein of Neisseria meningitidis, recently included in the family of trimeric autotransporter adhesins. In this study we present the structural and functional char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497701ea648f91e4cb9b001968a500b2
https://doi.org/10.1111/j.1365-2958.2006.05261.x
https://doi.org/10.1111/j.1365-2958.2006.05261.x
Autor:
Davide Serruto, Brunella Brunelli, Rino Rappuoli, Laura Santini, Elena Cartocci, Dan M. Granoff, Federica Di Marcello, Mario Contorni, Alessia Biolchi, Beatrice Aricò, Jeannette Adu-Bobie, Jo Anne Welsch, Donatella Mannucci, Daniele Veggi, Francesca Titta, Alessandro Bartalesi, Vanda Cinotti, Mariagrazia Pizza, Stefania Bambini, Barbara Capecchi, Maurizio Morandi, Vega Masignani, Elisa Ovidi, Laura Ciucchi, Francesca Ferlicca, Barbara Galli, Marzia Monica Giuliani, Enrico Luzzi, Silvana Savino, Maurizio Comanducci
Publikováno v:
Proceedings of the National Academy of Sciences. 103:10834-10839
Meningitis and sepsis caused by serogroup B meningococcus are two severe diseases that still cause significant mortality. To date there is no universal vaccine that prevents these diseases. In this work, five antigens discovered by reverse vaccinolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4241595c8145c57824a9c9377a83a3
https://doi.org/10.1073/pnas.0603940103
https://doi.org/10.1073/pnas.0603940103
Autor:
Rino Rappuoli, Beatrice Aricò, Mariagrazia Pizza, Barbara Capecchi, Annarita Taddei, Laura Ciucchi, Vega Masignani, Jeannette Adu-Bobie, Federica Di Marcello
Publikováno v:
Molecular Microbiology. 55:687-698
Neisseria meningitidis is a human pathogen, which is a major cause of sepsis and meningitis. The bacterium colonizes the upper respiratory tract of approximately 10% of humans where it lives as a commensal. On rare occasions, it crosses the epitheliu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e89b831f6d2e3412fbf2e8c48d6a2af
https://doi.org/10.1111/j.1365-2958.2004.04423.x
https://doi.org/10.1111/j.1365-2958.2004.04423.x
Autor:
Rino Rappuoli, Germano Ferrari, Nathalie Norais, Dan M. Granoff, Brunella Brunelli, Jeannette Adu-Bobie, Mariagrazia Pizza, Guido Grandi, Pietro Lupetti
Publikováno v:
Infection and Immunity. 72:1914-1919
GNA33 is a membrane-bound lipoprotein with murein hydrolase activity that is present in all Neisseria species and well conserved in different meningococcal isolates. The protein shows 33% identity to a lytic transglycolase (MltA) from Escherichia col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c069bf7256bf8fa6940b5d0ae72a5a6
https://doi.org/10.1128/iai.72.4.1914-1919.2004
https://doi.org/10.1128/iai.72.4.1914-1919.2004
Autor:
Maurizio Comanducci, Federica Di Marcello, Vega Masignani, Marzia Monica Giuliani, Enrico Balducci, Beatrice Aricò, Mariagrazia Pizza, Maria Scarselli, Davide Serruto, Rino Rappuoli, Stefania Bambini, Daniele Veggi, Silvana Savino, Jeannette Adu-Bobie
Publikováno v:
Molecular Microbiology. 50:1055-1067
Mono ADP-ribosyltransferases (ADPRTs) are a class of functionally conserved enzymes present in prokaryotic and eukaryotic organisms. In bacteria, these enzymes often act as potent toxins and play an important role in pathogenesis. Here we report a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5e9735d41ad22fb4f373656325a2c6
https://doi.org/10.1046/j.1365-2958.2003.03770.x
https://doi.org/10.1046/j.1365-2958.2003.03770.x
Autor:
Davide Serruto, Daniele Veggi, Beatrice Aricò, Jeannette Adu-Bobie, Mariagrazia Pizza, Rino Rappuoli, Maria Scarselli
Publikováno v:
Molecular Microbiology. 48:323-334
Neisseria meningitidis is a Gram-negative bacterium which colonizes the human upper respiratory tract. Occasionally, it translocates to the bloodstream causing sepsis and from there it can cross the blood-brain barrier and cause meningitis. Many of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7a362097722f7f7c5ab6cab07364f5
https://doi.org/10.1046/j.1365-2958.2003.03420.x
https://doi.org/10.1046/j.1365-2958.2003.03420.x
Autor:
Jeannette Adu-Bobie, Jo Anne Welsch, Brunella Brunelli, Stefania Bambini, Beatrice Aricò, Davide Serruto, Silvana Savino, Simon Kroll, Alessandro Pieri, Vega Masignani, Dan M. Granoff, Marzia Monica Giuliani, David J. Litt, Rino Rappuoli, Laura Santini, Maurizio Comanducci, Mariagrazia Pizza
Publikováno v:
The Journal of Experimental Medicine
Sepsis and meningitis caused by serogroup B meningococcus are devastating diseases of infants and young adults, which cannot yet be prevented by vaccination. By genome mining, we discovered GNA1870, a new surface-exposed lipoprotein of Neisseria meni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99484c8869ac19f1a2727dc67dca3651
http://europepmc.org/articles/PMC2193853
http://europepmc.org/articles/PMC2193853
Autor:
Dan M. Granoff, Rino Rappuoli, Laura Santini, Silvana Savino, Beatrice Aricò, Maurizio Comanducci, Mariagrazia Pizza, Jeannette Adu-Bobie, Stefania Bambini, Vega Masignani, Barbara Capecchi, Marzia Monica Giuliani, Brunella Brunelli, Dominique A. Caugant, Marirosa Mora
Publikováno v:
The Journal of Experimental Medicine
Neisseria meningitidis is a human pathogen, which, in spite of antibiotic therapy, is still a major cause of mortality due to sepsis and meningitis. Here we describe NadA, a novel surface antigen of N. meningitidis that is present in 52 out of 53 str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6a3201f29dcab216de926fcdcd928b
https://doi.org/10.1084/jem.20020407
https://doi.org/10.1084/jem.20020407
Autor:
Luiz Rachid Trabulsi, Gordon Dougan, Jeannette Adu-Bobie, Gill Douce, Gad Frankel, Azizedite Guedes Goncalves, Stuart Knutton, Christopher Bain
Publikováno v:
Journal of Clinical Microbiology. 36:662-668
Intimins are outer membrane proteins expressed by enteric bacterial pathogens capable of inducing intestinal attachment-and-effacement lesions. A eukaryotic cell-binding domain is located within a 280-amino-acid (Int280) carboxy terminus of intimin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7a7ffbf3dfbb1aa26a1013f68b2ebc
https://doi.org/10.1128/jcm.36.3.662-668.1998
https://doi.org/10.1128/jcm.36.3.662-668.1998
Autor:
Jeannette Adu-Bobie, Stuart Knutton, Gad Frankel, Gordon Dougan, Alan D. Phillips, Christopher Bain
Publikováno v:
Infection and Immunity. 65:1644-1652
Enteropathogenic Escherichia coli (EPEC) produces attaching and effacing (A/E) lesions in the intestinal mucosa. The intimate bacterial adhesion associated with A/E lesion formation is promoted by intimin, a 94-kDa EPEC surface protein. Anti-intimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fb46506812ef991aae16f765f18e88
https://doi.org/10.1128/iai.65.5.1644-1652.1997
https://doi.org/10.1128/iai.65.5.1644-1652.1997