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Dose-Adjusted EPOCH-Rituximab Combined With Fludarabine Provides an Effective Bridge to Reduced-Intensity Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Lymphoid Malignancies

Autor: Jeanne Odom, Robert M. Dean, Michael R. Bishop, Daniel H. Fowler, Kieron Dunleavy, Kelly Bryant, Thomas E. Hughes, Frances T. Hakim, Rachel B. Salit, Wyndham H. Wilson, Ronald E. Gress, Seth M. Steinberg, Terry J. Fry, Steven Z. Pavletic

Publikováno v: Journal of Clinical Oncology. 30:830-836

Purpose There is currently no standard chemotherapy regimen for patients with lymphoid malignancies being considered for reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation (RIC-alloHSCT). The ideal regimen would provide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9420eaf9718d7f1863da01cdfb6dbf00
https://doi.org/10.1200/jco.2011.37.0296

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EPOCH-F: a novel salvage regimen for multiple myeloma before reduced-intensity allogeneic hematopoietic SCT

Autor: S Jamshed, Jeanne Odom, D.H. Fowler, Kelly Bryant, F.T. Hakim, Sattva S. Neelapu, Seth M. Steinberg, Michael R. Bishop, Robert M. Dean

Publikováno v: Bone Marrow Transplantation. 46:676-681

There exists a need for effective salvage regimens for multiple myeloma patients being considered for reduced-intensity allogeneic hematopoietic SCT (RI-alloHSCT). We developed EPOCH-F, a regimen consisting of infusional etoposide, VCR and adriamycin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2f2d2b19e20f6b7910b7cf9db9b811
https://doi.org/10.1038/bmt.2010.173

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Assessment of the Hematopoietic Cell Transplantation Comorbidity Index in Non-Hodgkin Lymphoma Patients Receiving Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation

Autor: Seth M. Pollack, Jeanne Odom, Robert M. Dean, Seth M. Steinberg, Michael R. Bishop, Daniel H. Fowler

Publikováno v: Biology of Blood and Marrow Transplantation. 15:223-230

The hematopoietic cell transplantation comorbidity index (HCT-CI), a weighted index of 17 pretransplantation comorbidities, has been validated in nonmyeloablative and myeloablative allogeneic hematopoietic stem cell transplantation (HSCT) studies, bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b99731766b36a257b6a96188174a2c
https://doi.org/10.1016/j.bbmt.2008.11.023

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Clinical evidence of a graft-versus-lymphoma effect against relapsed diffuse large B-cell lymphoma after allogeneic hematopoietic stem-cell transplantation

Autor: Arne Kolstad, Catherine Chow, Claude Sportes, Jeanne Odom, Michael R. Bishop, Robert M. Dean, Seth M. Steinberg, D.H. Fowler, Steven Z. Pavletic, Nancy M. Hardy, Juan Gea-Banacloche, Ronald E. Gress, Stefania Pittaluga

Publikováno v: Annals of Oncology. 19:1935-1940

Background: A graft-versus-lymphoma effect against diffuse large B-cell lymphoma (DLBCL) is inferred by sustained relapse-free survival after allogeneic stem-cell transplantation; however, there are limited data on a direct graft-versus-lymphoma effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dc17204901e889b1fb37c8d4e6e02e
https://doi.org/10.1093/annonc/mdn404

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Association of serum interleukin-7 levels with the development of acute graft-versus-host disease

Autor: Michael R. Bishop, Robert M. Dean, Seth M. Steinberg, Terry J. Fry, Frances T. Hakim, Daniel H. Fowler, Crystal L. Mackall, Jason Foley, Jeanne Odom, R.E. Gress

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(35)

PurposeMorbidity from acute graft-versus-host disease (GVHD) limits the success of allogeneic hematopoietic stem-cell transplantation (HSCT) to treat malignancy. Interleukin-7 (IL-7), the principal homeostatic cytokine for T cells, is required for ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56924c5067a7066394dd544af5fd2016
https://pubmed.ncbi.nlm.nih.gov/19001329

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Age-dependent incidence, time course, and consequences of thymic renewal in adults

Autor: Catherine Chow, Claude Kasten-Sportes, Rosemarie Cepeda, Elizabeth C. Jones, Barbara A. Vance, Jeanne Odom, Sarfraz Memon, Ronald E. Gress, Barbara L. Christensen, Frances T. Hakim, Crystal L. Mackall

Homeostatic regulation of T cells involves an ongoing balance of new T cell generation, peripheral expansion, and turnover. The recovery of T cells when this balance is disrupted provides insight into the mechanisms that govern homeostasis. In a long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b718ae23debd154172354d6fa38de9e6
https://europepmc.org/articles/PMC1064981/

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Clinical 'cytokine storm' as revealed by monocyte intracellular flow cytometry: correlation of tumor necrosis factor alpha with severe gut graft-versus-host disease

Autor: Jeanne Odom, Ronald E. Gress, Jeannie Whit Shan Hou, Kate Castro, Jason Foley, Michael R. Bishop, Daniel H. Fowler, Juan Gea-Banacloche, Claude Kasten-Sportes, Seth M. Steinberg

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2(3)

Background & Aims: Gut graft-versus-host disease (GVHD) contributes significantly to lethality after allogeneic hematopoietic stem-cell transplantation (HSCT). In murine models, macrophage secretion of interleukin 1α (IL-1α) and tumor necrosis fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05d304133c75aafc89e6a1589892b83
https://pubmed.ncbi.nlm.nih.gov/15017608

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