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pro vyhledávání: '"Jeanne M. Snyder"'
Autor:
Jeanne M. Snyder
Publikováno v:
Pulmonary Surfactant: Biochemical, Functional, Regulatory, and Clinical Concepts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ac45174b09bc5c3c3909ed40ce257a2
https://doi.org/10.1201/9780367812812-5
https://doi.org/10.1201/9780367812812-5
Autor:
Thomas J. Schmidt, Troy A McCarthy, Mark R. Garbrecht, Jonathan M. Klein, Jeanne M. Snyder, Zygmunt Krozowski
Publikováno v:
Pediatric Research. 62:26-31
11-Beta hydroxysteroid dehydrogenase type 2 (HSD2) oxidizes the biologically active glucocorticoid (GC), cortisol, to inactive cortisone. We characterized HSD2 gene expression and activity in human adult and fetal lung tissues and in cultured fetal l
Autor:
Joel N. Kline, Jeanne M. Snyder, Peter S. Thorne, Katarina Kulhankova, Misty L. White, Caroline L.S. George, Aditya Mahajan
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L512-L522
The hygiene hypothesis suggests that early life exposure to a nonhygienic environment that contains endotoxin reduces the risk of developing allergic diseases. The mechanisms underlying the hygiene hypothesis are unclear and may involve subtle immune
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 33:622-628
Bronchopulmonary dysplasia in premature infants is characterized by inhibited alveolarization and vasculogenesis. Our goal was to generate a mouse model of inhibited alveolarization by the administration of an inhibitor of angiogenesis. We then exami
Autor:
Laila Dahmoush, Rebecca E. Oberley, Kelli L. Goss, Kevin A. Ault, Erika C. Crouch, Jeanne M. Snyder
Publikováno v:
The Prostate. 65:241-251
OBJECTIVES Surfactant protein D (SP-D) is a member of the collectin family of proteins, which are involved in host defense mechanisms in the lung. In the present study, we found that SP-D is produced in the human prostate where it may play a role in
Autor:
Stephen E. McGowan, Hui-Hui Dai, Jeanne M. Snyder, Vincent Giguère, Kelli L. Goss, Sheila K. Jackson, Peter J. Bangsund, Melinda Jenkins-Moore
Publikováno v:
Pediatric Research. 57:384-391
Retinoids bind to nuclear receptors [retinoic acid receptors (RARs) and retinoid X receptors]. RARbeta, one of three isoforms of RARs (alpha, beta, and gamma), is expressed in the fetal and adult lung. We hypothesized that RARbeta plays a role in alv
Autor:
T. Neff, Erika C. Crouch, Rebecca E. Oberley, Kevin A. Ault, Kavita R. Khubchandani, Jeanne M. Snyder
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 287:L296-L306
Chlamydiae are intracellular bacterial pathogens that infect mucosal surfaces, i.e., the epithelium of the lung, genital tract, and conjunctiva of the eye, as well as alveolar macrophages. In the present study, we show that pulmonary surfactant prote
Autor:
Jeanne M. Snyder, Olga L. Miakotina
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L1210-L1219
Surfactant protein A (SP-A), the most abundant pulmonary surfactant protein, plays a role in innate host defense and blocks the inhibitory effects of serum proteins on surfactant surface tension-lowering properties. SP-A mRNA and protein are downregu
Autor:
Peter S. Thorne, Marsha E. O'Neill, Caroline L.S. George, Jeanne M. Snyder, David A. Schwartz, Misty L. White
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 285:L1337-L1344
Chronically inhaled endotoxin, which is ubiquitous in many occupational and domestic environments, can adversely affect the respiratory system resulting in an inflammatory response and decreased lung function. Surfactant-associated protein A (SP-A) i
Autor:
Jeanne M. Snyder, Olga L. Miakotina
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 283:L418-L427
Surfactant protein A (SP-A), the major lung surfactant-associated protein, mediates local defense against pathogens and modulates inflammation in the alveolus. Tumor necrosis factor (TNF)-alpha, a proinflammatory cytokine, inhibits SP-A gene expressi