Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeanne Lapin"'
Autor:
Ella Dvorkin, Ricardo A. Cruciani, Bruce Culliney, Peter Homel, Jeanne Lapin, Stephen Malamud, Russell K. Portenoy, Nora Esteban-Cruciani
Publikováno v:
Journal of Pain and Symptom Management. 32:551-559
Carnitine deficiency is among the many metabolic disturbances that may contribute to fatigue in patients with cancer. Administration of exogenous L-carnitine may hold promise as a treatment for this common symptom. Little is known about L-carnitine s
Autor:
Ricardo A. Cruciani, Jeanne Lapin, Bruce Culliney, Peter Homel, Russell K. Portenoy, S. Malamud, E. Dvorkin, Lauren Shaiova, Nora Esteban-Cruciani, Pauline Lesage, Stewart B. Fleishman, E Klein
Publikováno v:
Annals of the New York Academy of Sciences. 1033:168-176
Nutritional factors are among the postulated causes of fatigue, a highly prevalent symptom in the cancer population, with serious impact on patients' quality of life. Deficiency of the micronutrient carnitine may play a role by reducing energy produc
Autor:
Ira J. Dunkel, Tanya Polyak, Russell K. Portenoy, Maura E. Byrnes, John J. Collins, Howard T. Thaler, Jeanne Lapin, Traci Nadel, Bruce D. Rapkin
Publikováno v:
Journal of Pain and Symptom Management. 19:363-377
The purpose of this study was to determine symptom prevalence, characteristics, and distress in children with cancer. The Memorial Symptom Assessment Scale (MSAS) 10-18, a 30-item patient-rated instrument adapted from a previously validated adult ver
Autor:
John J. Collins, Leah N. Palmer, Russell K. Portenoy, Jeanne Lapin, Sharon M. Weinstein, Ira J. Dunkel, Charles E. Inturrisi, Suneel K. Gupta
Publikováno v:
The Journal of Pediatrics. 134:319-323
Objectives: (1) To assess the feasibility and tolerability of the therapeutic transdermal fentanyl system (TTS-fentanyl) by using a clinical protocol developed for children with cancer pain. (2) To estimate the pediatric pharmacokinetic parameters of
Autor:
Jeanne Lapin, Ronald Goldblum, Jane M. Ingham, Jian H. Johnson, Mary Jeanne Kreek, Charles E. Inturrisi, Augusto Caraceni, Nathan I. Cherny, Russell K. Portenoy, Paul J. Tiseo
Publikováno v:
Clinical Drug Investigation. 17:33-42
Objective: This pilot study was developed to acquire preliminary data concerning the analgesic efficacy and tolerability of dynorphin A(1–13), a 13 amino acid fragment of the endogenous opioid peptide dynorphin A(1–17), in opioid-treated patients
Autor:
Kathleen M. Foley, Raymond W. Houde, Jeanne Lapin, A. G. Rogers, Russell K. Portenoy, Stanley L. Wallenstein
Publikováno v:
Pain. 41:5-13
A direct comparison of the analgesic activities of heroin and hydromorphone was carried out in cancer patients with postsurgical pain. Intramuscular doses of 5 and 10 mg of heroin were compared with 1 and 2 mg of hydromorphone in a randomized, double
Autor:
Daniel Shasha, Jeanne Lapin, Louis B. Harrison, Kenneth S. Hu, Russell K. Portenoy, Lorraine S. Manco, Lauren Shaiova
Publikováno v:
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 12(4)
Oral transmucosal fentanyl citrate (OTFC; ACTIQ) incorporates fentanyl into a lozenge allowing drug delivery through the oral mucosa resulting in rapid pain relief. OTFC is effective for breakthrough pain and could be particularly useful in patients
Autor:
Howard T. Thaler, Russell K. Portenoy, Jeanne Lapin, Kathleen M. Foley, Paul J. Tiseo, Charles E. Inturrisi
Publikováno v:
Pain. 61(1)
The active morphine metabolite, morphine-6-glucuronide (M-6-G), may contribute to both the analgesia and the adverse effects observed during morphine (MOR) therapy. To evaluate the relationship between M-6-G and adverse effects, we measured steady-st
Autor:
Suneel K. Gupta, Kathleen M. Foley, Charles E. Inturrisi, Mary Layman, Russell K. Portenoy, Mary Southam, Jeanne Lapin
Publikováno v:
Anesthesiology. 78(1)
The transdermal therapeutic system (fentanyl), or TTS(fentanyl), continuously delivers fentanyl for up to 72 h. The transdermal therapeutic system (fentanyl)-100 delivers approximately 100 micrograms/h. The repeated dose pharmacokinetics of this drug
Autor:
Mary Layman, M. G. Malkin, Charles E. Inturrisi, Howard T. Thaler, E. Khan, Jeanne Lapin, Russell K. Portenoy, Daniel J. Cerbone, Kathleen M. Foley
Publikováno v:
Neurology. 41(9)
Morphine-6-glucuronide (M-6-G) is an active metabolite that may contribute to the clinical effects produced by systemic administration of morphine. To help clarify the extent to which M-6-G may cross the blood-brain barrier and exert effects, we empl