Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeanne K. Bloom"'
Autor:
Jeanne K. Bloom, Timothy J. Seabrook, Melitza Iglesias, Cynthia A. Lemere, Edward T. Spooner, Dominic M. Walsh
Publikováno v:
Neurobiology of Aging. 25:1141-1151
Amyloid beta (A beta) immunization of amyloid precursor protein (APP)-transgenic (tg) mice with human A beta induces humoral immunity, however, the immune response to endogenous rodent A beta is unknown. Fourteen-month J20 APP-tg mice and non-tg litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f986ed4fb4b80e1c4d6232da0f8c351
https://doi.org/10.1016/j.neurobiolaging.2003.12.008
https://doi.org/10.1016/j.neurobiolaging.2003.12.008
Publikováno v:
Vaccine. 22:4075-4083
The cerebral accumulation of beta-amyloid (Abeta) is a pathological hallmark of Alzheimer's disease (AD). Abeta vaccination or anti-Abeta specific antibodies may be a possible therapeutic option for AD. Previously, we demonstrated variation in the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad219f98411b302a1aaa24b41fb1940e
https://doi.org/10.1016/j.vaccine.2004.03.061
https://doi.org/10.1016/j.vaccine.2004.03.061
Autor:
Edward T. Spooner, Timothy J. Seabrook, Jeanne K. Bloom, Jodi F. Leverone, Chica Mori, Melitza Iglesias, Cynthia A. Lemere
Publikováno v:
Neurochemical Research. 28:1017-1027
Alzheimer's disease is the most prevalent form of dementia worldwide. Therapies are desperately needed to prevent and cure the disease. Mouse models of amyloid-β deposition [APP and PSAPP transgenic (tg) mice] have been useful in determining the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ef452f589dfa44f7521e07e62cd5d78
https://doi.org/10.1023/a:1023203122036
https://doi.org/10.1023/a:1023203122036
Autor:
Jeanne K. Bloom, Edward T. Spooner, Katelyn Thomas, Timothy J. Seabrook, Marcel Maier, Cynthia A. Lemere, Liying Jiang, Gal Bitan
Publikováno v:
Neurobiology of aging. 28(6)
Immunization of humans and APP-tg mice with full-length beta-amyloid (Abeta) results in reduced cerebral Abeta levels. However, due to adverse events in the AN1792 trial, alternative vaccines are required. We investigated dendrimeric Abeta1-15 (dAbet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916641a4bc7f3402e4c403b1a20dbb10
https://pubmed.ncbi.nlm.nih.gov/16725229
https://pubmed.ncbi.nlm.nih.gov/16725229
Autor:
Dora Louard, Dennis J. Selkoe, Frank R. Ervin, Amy Beierschmitt, Timothy J. Seabrook, Melitza Iglesias, Roberta M. Palmour, Edward T. Spooner, Jeanne K. Bloom, Diana Li, Jessica B. Zheng, Jodi F. Leverone, Cynthia A. Lemere
Publikováno v:
The American journal of pathology. 165(1)
Amyloid beta (Abeta) protein immunotherapy lowers cerebral Abeta and improves cognition in mouse models of Alzheimer's disease (AD). Here we show that Caribbean vervet monkeys (Chlorocebus aethiops, SK) develop cerebral Abeta plaques with aging and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65576d3bb3aefa8954be076b2840799f
https://pubmed.ncbi.nlm.nih.gov/15215183
https://pubmed.ncbi.nlm.nih.gov/15215183
Autor:
Cynthia A, Lemere, Edward T, Spooner, Jodi F, Leverone, Chica, Mori, Melitza, Iglesias, Jeanne K, Bloom, Timothy J, Seabrook
Publikováno v:
Neurochemical research. 28(7)
Alzheimer's disease is the most prevalent form of dementia worldwide. Therapies are desperately needed to prevent and cure the disease. Mouse models of amyloid-beta deposition [APP and PSAPP transgenic (tg) mice] have been useful in determining the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe8babe9bca632538046c914732de593
https://pubmed.ncbi.nlm.nih.gov/12737526
https://pubmed.ncbi.nlm.nih.gov/12737526
Autor:
Edward T. Spooner, Timothy J. Seabrook, Gal Bitan, Cynthia A. Lemere, Jeanne K. Bloom, Marcel Maier
Publikováno v:
Neurobiology of Aging. 25:S592
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9446f9c7d8f292349b082947b239f122
https://doi.org/10.1016/s0197-4580(04)81972-9
https://doi.org/10.1016/s0197-4580(04)81972-9