Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeanne E. McKeon"'
Autor:
Reddy Ranjith K. Sama, Claudia Fallini, Rodolfo Gatto, Jeanne E. McKeon, Yuyu Song, Melissa S. Rotunno, Saul Penaranda, Izrail Abdurakhmanov, John E. Landers, Gerardo Morfini, Scott T. Brady, Daryl A. Bosco
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Mutations in Fused in Sarcoma/Translocated in Liposarcoma (FUS) cause familial forms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by progressive axonal degeneration mainly affecting motor neurons. Evidenc
Externí odkaz:
https://doaj.org/article/f67025a8d9b84438822ee997bac6b02a
Autor:
Daryl A. Bosco, Francesca Massi, Brittany R. Morgan, Eric J. Schmidt, Salome Funes, Antoine Jégou, Sivakumar Boopathy, Osman Bilsel, Lauren C. O’Connor, Jeanne E. McKeon
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2024605118. ⟨10.1073/pnas.2024605118⟩
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2024605118. ⟨10.1073/pnas.2024605118⟩
International audience; Profilin-1 (PFN1) plays important roles in modulating actin dynamics through binding both monomeric actin and proteins enriched with polyproline motifs. Mutations in PFN1 have been linked to the neurodegenerative disease amyot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439ea8326d2e7709ba14eb274303e794
https://doi.org/10.1073/pnas.2024605118
https://doi.org/10.1073/pnas.2024605118
Autor:
E Danielle Dean, Lydia M Mexas, Natalie L Cápiro, Jeanne E McKeon, Mahlon R DeLong, Kurt D Pennell, Jonathan A Doorn, Vin Tangpricha, Gary W Miller, Marian L Evatt
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39227 (2012)
Recent clinical evidence supports a link between 25-hydroxyvitamin D insufficiency (serum 25-hydroxyvitamin D [25(OH)D] levels
Externí odkaz:
https://doaj.org/article/4de7426d10e342cea54c7441f927f4d9
Autor:
Jeanne E. McKeon, Kristen E. Hokenson, Cristina Suarez, Sarah A. Kim, Scott D. Edmands, Jennifer A. Tyson, Emily E. Stackpole, Adam C. Hall, Laura L. Campbell, Hanna Sherrill
Publikováno v:
Toxicology. 283:1-7
General anaesthetics are proposed to cause unconsciousness by modulating neuronal excitability in the mammalian brain through mechanisms that include enhancement of inhibitory GABA A receptor currents and suppression of excitatory glutamate receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f6e87ec53a511c3df75bba80266cbe
https://doi.org/10.1016/j.tox.2011.01.014
https://doi.org/10.1016/j.tox.2011.01.014
Publikováno v:
Cellular and molecular life sciences : CMLS. 72(9)
Ubiquitin C-terminal hydrolase L1 (UCH-L1) is a key neuronal deubiquitinating enzyme which is mutated in Parkinson disease (PD) and in childhood-onset neurodegenerative disorder with optic atrophy. Furthermore, reduced UCH-L1 protein levels are assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473c2a65d8171489ee4f1be67c2b0af
https://pubmed.ncbi.nlm.nih.gov/25403879
https://pubmed.ncbi.nlm.nih.gov/25403879
Autor:
Tania F. Gendron, Zachary Kennedy, Nicholas Wightman, Jake Metterville, Chris J. Jung, Juhyun Kim, Christian Mueller, Dennis W. Dickson, Kevin B. Boylan, Lillian M. Daughrity, Alexandra Weiss, Gabriela Toro Cabrera, Solange P. Brown, Johnny Salameh, Owen M. Peters, Huaming Sun, Helene Tran, Pieter J. de Jong, Robert H. Brown, Jeanne E. McKeon, Fen-Biao Gao, Leonard Petrucelli, Daryl A. Bosco, H. Robert Horvitz, Yong Jie Zhang, Peter C. Sapp, Ziqiang Lin
Publikováno v:
PMC
A non-coding hexanucleotide repeat expansion in the C9ORF72 gene is the most common mutation associated with familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). To investigate the pathological role of C9ORF72 in these dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67850a51cfbb578720443a75b0a99709