Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jeanne Cook-Moreau"'
Autor:
Nicolas Denis-Lagache, Christelle Oblet, Tiffany Marchiol, Audrey Baylet, Ophélie Têteau, Iman Dalloul, Zeinab Dalloul, Lina Zawil, Ophélie Dézé, Jeanne Cook-Moreau, Alexis Saintamand, Hend Boutouil, Ahmed Amine Khamlichi, Claire Carrion, Sophie Péron, Sandrine Le Noir, Brice Laffleur, Michel Cogné
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn mature B cells, activation-induced deaminase reshapes Ig genes through somatic hypermutation and class switch recombination of the Ig heavy chain (IgH) locus under control of its 3’ cis-regulatory region (3’RR). The 3’RR is itsel
Externí odkaz:
https://doaj.org/article/138b735a8308469d92f827d4c9644e6a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells undergo genetic rearrangements at immunoglobulin gene (Ig) loci during B cell maturation. First V(D)J recombination occurs during early B cell stages followed by class switch recombination (CSR) and somatic hypermutation (SHM) which occur dur
Externí odkaz:
https://doaj.org/article/8cbebcb272e14a89a8116dcb314fff75
Autor:
Nour Ghazzaui, Hussein Issaoui, Mélissa Ferrad, Claire Carrion, Jeanne Cook-Moreau, Yves Denizot, François Boyer
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 28-39 (2020)
Abstract: Numerous B-cell lymphomas feature translocations linking oncogenes to different locations in the immunoglobulin heavy chain (IgH) locus. During Burkitt lymphoma (BL), IgH breakpoints for c-myc translocation stand either close to JH segments
Externí odkaz:
https://doaj.org/article/f70300e450814e969840ff91027c990b
Autor:
Zeinab Dalloul, Marie Best, Pauline Chenuet, Iman Dalloul, Sandrine Le Noir, Dieudonnée Togbé, Mylène Gador, Bernhard Ryffel, Valerie FJ Quesniaux, Yolla El Makhour, François Boyer, Jean‐Claude Aldigier, Jeanne Cook‐Moreau, Nicolas Fazilleau, Michel Cogné
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological pr
Externí odkaz:
https://doaj.org/article/7f4552b0dd5f47e48599bdbc8b3cbc6d
Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chromosomal translocations linking various oncogenes to transcriptional enhancers of the immunoglobulin heavy chain (IgH) locus are often implicated as the cause of B-cell malignancies. Two major IgH transcriptional enhancers have been reported so fa
Externí odkaz:
https://doaj.org/article/aac81d943aea4a68b0ed166f0f13f2e1
Autor:
Iman Dalloul, François Boyer, Zeinab Dalloul, Amandine Pignarre, Gersende Caron, Thierry Fest, Fabrice Chatonnet, Céline Delaloy, Anne Durandy, Robin Jeannet, Emilie Lereclus, Hend Boutouil, Jean-Claude Aldigier, Sophie Péron, Sandrine Le Noir, Jeanne Cook-Moreau, Michel Cogné
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1007721 (2019)
B-cell activation yields abundant cell death in parallel to clonal amplification and remodeling of immunoglobulin (Ig) genes by activation-induced deaminase (AID). AID promotes affinity maturation of Ig variable regions and class switch recombination
Externí odkaz:
https://doaj.org/article/b008f55c724e43988bbb8e81994f41ac
Autor:
Yoanne Mousseau, Dany Leclers, Karine Faucher-Durand, Jeanne Cook-Moreau, Anne-Sophie Lia-Baldini, Michel Rigaud, Franck G. Sturtz
Publikováno v:
BioTechniques, Vol 43, Iss 4, Pp 509-516 (2007)
Cell chemotaxis is frequently required in normal or pathological situations such as invasion, metastasis, and tumor angiogenesis and may involve many different cell types. At present, no device can simultaneously (i) make morphological observations,
Externí odkaz:
https://doaj.org/article/f6f71084683347ff8907dfd942484e6f
Autor:
Melissa Ferrad, Nour Ghazzaui, Hussein Issaoui, Emilie Drouineau, Christelle Oblet, Tiffany Marchiol, Jeanne Cook-Moreau, Yves Denizot
Publikováno v:
Leukemia & lymphoma
Leukemia & lymphoma, 2022, 63 (9), pp.2114-2125. ⟨10.1080/10428194.2022.2064989⟩
Leukemia & lymphoma, 2022, 63 (9), pp.2114-2125. ⟨10.1080/10428194.2022.2064989⟩
International audience; The 3' regulatory region (3'RR) located downstream from the Cα gene is the conductor of transcription, accessibility, and remodeling of the IgH locus at mature B-cell stages. Convincing demonstrations of the essential contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24927019f1819309dece8e6fb2af30d3
https://doi.org/10.1080/10428194.2022.2064989
https://doi.org/10.1080/10428194.2022.2064989
Autor:
Hussein Issaoui, Mélissa Ferrad, Tiffany Marchiol, Nour Ghazzaui, Yves Denizot, Jeanne Cook-Moreau
Publikováno v:
Immunology Letters. 240:12-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc92d2d5a68a5faff1e6bc2c4c52dc9e
https://doi.org/10.1016/j.imlet.2021.09.010
https://doi.org/10.1016/j.imlet.2021.09.010
Autor:
Claire Carrion, Nour Ghazzaui, Jeanne Cook-Moreau, François Boyer, Mélissa Ferrad, Hussein Issaoui, Y. Denizot
Publikováno v:
Blood Advances. 4:28-39
Numerous B-cell lymphomas feature translocations linking oncogenes to different locations in the immunoglobulin heavy chain (IgH) locus. During Burkitt lymphoma (BL), IgH breakpoints for c-myc translocation stand either close to J(H) segments or with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0524e8c66f9bdf131c2b123ac11d1be5
https://doi.org/10.1182/bloodadvances.2019000845
https://doi.org/10.1182/bloodadvances.2019000845