Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jeanne, Magram"'
Autor:
Sarah Grant, Kristen Johnson, Tom Thomas, Gerard Honig, Piotr Bielecki, Calliope Dendrou, Sean Guo, Ruth Kulicke, Ping Li, Larry L’Italien, Noah Spies, Nicolas Stransky, Holm Uhlig, Mukund Varma, Simon Travis, Christopher Buckley, Jeanne Magram
Publikováno v:
Inflammatory Bowel Diseases. 29:S52-S53
Ulcerative colitis (UC) and Crohn’s disease (CD) are complex and heterogenous diseases characterized by chronic and progressive inflammation of the digestive tract. Single cell RNA sequencing combined with computational biology provides unprecedent
Autor:
Jeanne Magram, Ying Fu, Stephane Angers, Kevin K. Lin, Melissa Beilschmidt, Jean-Philippe Julien, Alejandro Duque, Jason Moffat, Keith Mascall, Francine Lui, Sachdev S. Sidhu, Swetha Raman, Minh D. To, Mark Ng, Yazen Jmeian, Minerva Fernandez, Xiaowei Wang, Guohua Pan, Angus M. Sinclair, Johan E. S. Fransson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6812-6817
Aberrant activation of Wnt/β-catenin signaling occurs frequently in cancer. However, therapeutic targeting of this pathway is complicated by the role of Wnt in stem cell maintenance and tissue homeostasis. Here, we evaluated antibodies blocking 6 of
Autor:
Kristen, Johnson, Kymberly, Levine, Joseph, Sergi, Jean, Chamoun, Rachel, Roach, Jacqueline, Vekich, Mike, Favis, Mark, Horn, Xianjun, Cao, Brian, Miller, William, Snyder, Dikran, Aivazian, William, Reagan, Edwin, Berryman, Jennifer, Colangelo, Victoria, Markiewicz, Cedo M, Bagi, Thomas P, Brown, Anthony, Coyle, Moosa, Mohammadi, Jeanne, Magram
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 32(10)
Fibroblast growth factor 23 (FGF23) is the causative factor of X-linked hypophosphatemia (XLH), a genetic disorder effecting 1:20,000 that is characterized by excessive phosphate excretion, elevated FGF23 levels and a rickets/osteomalacia phenotype.
Autor:
Zainab Haybe, Mark Ng, Melissa Beilschmidt, Minh D. To, Kevin K. Lin, Jeanne Magram, James Pan, Jean-Philippe Julien, Yazen Jmeian, Sachdev S. Sidhu, Johan E. S. Fransson, Stephane Angers, Jason Moffat, Angus Sinclair, Minerva Fernandez, Swetha Raman, Keith Mascall, Ying Fu, Francine Lui
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:a297-a297
Autor:
Monica Pascual, Naimish Pandya, Joan Seoane, Kimberly Hoffman, Robin M. Hallett, Ada Sala, Angus M. Sinclair, Judit Anido, Vanessa Chiganças, Robert Wasserman, Patricia Giblin, Isabel Huber-Ruano, Johan E. S. Fransson, Jeanne Magram, Swetha Raman, Jean-Philippe Julien
Publikováno v:
Cancer Research. 78:1751-1751
Leukemia Inhibitory Factor (LIF) is a member of the IL-6 family of cytokines and is involved in many physiological and pathological processes including the promotion of an immunosuppressive environment to support embryo implantation, down-regulation
Autor:
Patricia Giblin, Judit Anido, Lillian L. Siu, Anna Spreafico, Jeanne Magram, Robert Wasserman, Alison M. Schram, José Baselga, Irene Brana, David M. Hyman, Robin Hallet, Joan Seoane, Isabel Huber Ruano, Kimberly Hoffman, Josep Tabernero, Naimish Pandya
Publikováno v:
Journal of Clinical Oncology. 36:TPS2602-TPS2602
TPS2602Background: Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine involved in many physiological and pathological processes. LIF is highly expressed in a subset of tumors across multipl...
Autor:
Angus M. Sinclair, Jeanne Magram, Ada Sala, Kimberly Hoffman, Robert Wasserman, Robin M. Hallett, Judit Anido, Joan Seoane, Naimish Pandya, Monica Pascual, Vanessa Chiganças, Isabel Huber Ruano, Patricia Giblin
Publikováno v:
Molecular Cancer Therapeutics. 17:LB-B34
Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine involved in many physiological and pathological processes. LIF is highly expressed in a subset of tumors across multiple tumor types and has been shown to correlate with poor prognosis. LIF i
Autor:
Virmondes Rodrigues-Júnior, Kurt A. Heldwein, Pamela J. Ovendale, Anthony A. Frank, Vanja Lazarevic, Michael Tovey, Hua Su, N. B. Pefaur, Terry K. Means, Bing Chen, Reiling Liao, Ammini Jeevan, Jessica Ferrante, Michael Reed, Patrick J. Brennan, Kenneth H. Grabstein, Pilar Domenech, Rebecca A. Lines, Kerry Rutter, Amy Bergtold, Martin I. Voskuil, Christopher C. Dascher, Robert N. Husson, Sahadevan Raman, Steven G. Reed, Roberto Badaró, Gilla Kaplan, Karl Drlica, Charles A. Scanga, Bryan W. Jones, Stefanie N. Vogel, Clifton E. Barry, Ian M. Orme, Natalya Serbina, Tao Lu, Gary K. Schoolnik, Robert Barthel, David R. Sherman, Kathryn DeReimer, Liana Tsenova, John R. Murphy, Steven A. Porcelli, Joanne Turner, Yukari C. Manabe, Eunice Y. Tsai, Dirk Wagner, Philip Hopewell, Michael B. Brenner, Marcos Burgos, JoAnne L. Flynn, A. S. Heinzel, Anne E. Goldfeld, David N. McMurray, Toshiko Yamamoto, Thomas C. Terwilliger, John Chan, Andrea M. Cooper, Sherry Freeman, Xiaoling Puyang, Taeksun Song, Kenji Hiromatsu, Mark R. Alderson, Holly Scott, Alla V. Tsytsykova, Rhea N. Coler, Yong-jun Li, Jeanne Magram, Christine L. Hatem, Kendra Bodnar, Luiz E. Bermudez, Yasir A. W. Skeiky, Diana B. Pedral-Sampaio, L. Zhu, Maria I. Harrell, Gui Liu, William R. Bishai, Kristi M. Guinn, William R. Jacobs, Victoria H. Freedman, André Kipnis, David M. Lewinsohn, Stoyan Bardarov, Amy K. Barczak, Kenneth P. LeClair, Matthew J. Fenton, Xiaowei Xiong, Eduardo Martins Netto, Antonio Campos-Neto, Peter M. Small, Todd M. Lasco, Claudia Manca, Deborah A. Lewinsohn, Charles L. Daley
Publikováno v:
Tuberculosis. 82:113-135
Publikováno v:
Scopus-Elsevier
Recent evidence suggests that absence of the IL-12p40 subunit is more detrimental to the generation of protective responses than is the absence of the p35 subunit. To determine whether this is the case in tuberculosis, both p35 and p40 knockout mice
Publikováno v:
The Journal of Immunology. 165:6221-6228
Two subunits of the IL-12 receptor (IL-12R), IL-12R beta 1 and IL-12R beta 2, have been identified and cloned. Previous studies demonstrated that the IL-12R beta 1 subunit was required for mouse T and NK cells to respond to IL-12 in vivo. To investig