Výsledky vyhledávání - "Jeanine Walenga"

Akademický článek

Glycemic Control and Plasma Levels of Pro-Inflammatory and Pro-Thrombotic Biomarkers in Diabetic Patients Presenting with Acute Pulmonary Embolism

Autor: Alexander O’Hara BS, Jacob Pozin BS, Amir Darki MD, MSc, Fakiha Siddiqui BDS, Debra Hoppensteadt PhD, Jeanine Walenga PhD, Jawed Fareed PhD, Bulent Kantarcioglu MD

Publikováno v: Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)

Type I and type II diabetes are closely associated with a pro-inflammatory state and to a pro-thrombotic state. The role of glycemic control in pulmonary embolism (PE) is poorly understood and requires additional investigation. The aim of this study

Externí odkaz: https://doaj.org/article/b6d3e73ab61346bcbbc66709c9086fdb

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Akademický článek

Predictive Role of Blood Cellular Indices and Their Relationship with Endogenous Glycosaminoglycans as Determinants of Inflammatory Biomarkers in Pulmonary Embolism

Autor: Bulent Kantarcioglu MD, Amir Darki MD, MSc, Fakiha Siddiqui BDS, Emily Krupa BS, Mehmet Vural MD, Murat Kacmaz MD, Debra Hoppensteadt PhD, Omer Iqbal MD, Walter Jeske PhD, Jeanine Walenga PhD, Cafer Adiguzel MD, Jawed Fareed PhD

Publikováno v: Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)

Introduction In this study, we profiled the levels of blood cellular indices, endogenous glycosaminoglycans (GAGs) and inflammatory biomarkers in a cohort comprised of pulmonary embolism (PE) patients, to determine their inter-relationships. Identifi

Externí odkaz: https://doaj.org/article/110980c3dd7e456e97b9d9aa585a6b9c

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Akademický článek

Zika and Chikungunya Virus and Risk for Venous Thromboembolism

Autor: Eduardo Ramacciotti MD, PhD, Leandro B. Agati PhD, Valéria C. R. Aguiar MD, Nelson Wolosker MD, PhD, João C. Guerra MD, PhD, Roque P. de Almeida MD, PhD, Juliana Cardoso Alves MD, Renato D. Lopes MD, PhD, Thomas W. Wakefield MD, Anthony J. Comerota MD, Jeanine Walenga PhD, Jawed Fareed PhD

Publikováno v: Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019)

A variety of viral infections are associated with hypercoagulable states and may be linked to the development of deep venous thrombosis and pulmonary embolism. The Zika and Chikungunya viral infections spread through the South and Central American co

Externí odkaz: https://doaj.org/article/cb6d40a98a884ede8da3150135de779f

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Akademický článek

Bovine Mucosal Heparins Are Comparable to Porcine Mucosal Heparin at USP Potency Adjusted Levels

Autor: Walter Jeske, Ahmed Kouta, Ambar Farooqui, Fakiha Siddiqui, Varun Rangnekar, Manoj Niverthi, Rajan Laddu, Debra Hoppensteadt, Omer Iqbal, Jeanine Walenga, Jawed Fareed

Publikováno v: Frontiers in Medicine, Vol 5 (2019)

Introduction: Bovine mucosal heparins (BMH) are currently being developed for re-introduction for both medical and surgical indications. BMH active pharmaceutical ingredient (API) exhibits a somewhat weaker USP potency when compared to PMHs. We hypot

Externí odkaz: https://doaj.org/article/0b7d4ebb78d444f6ac449696d40f66a4

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Multiplex genome editing of mammalian cells for producing recombinant heparin

Autor: Bryan E. Thacker, Kristen J. Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P. Kellman, Nathan E. Lewis, Zhenping Wang, Anna Di Nardo, Susan T. Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D. Esko, Charles A. Glass

Publikováno v: Metabolic Engineering. 70:155-165

Heparin is an essential anticoagulant used for treating and preventing thrombosis. However, the complexity of heparin has hindered the development of a recombinant source, making its supply dependent on a vulnerable animal population. In nature, hepa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4eb39db7acb0dc166acf6cadcd29e8
https://doi.org/10.1016/j.ymben.2022.01.002

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Development of a Synthetic Heparin Pentasaccharide as an Antithrombotic Drug

Autor: Jeanine Walenga, M.M. Samama, Jawed Fareed, Walter Jeske

Publikováno v: New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded ISBN: 9780824707958
New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d9f7bf0f76689ad1e85ad0828bdb976
https://doi.org/10.1201/9780203909317.ch15

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