Výsledky vyhledávání - "Jeanine Saba"

Induction of human cytotoxic T lymphocytes that preferentially recognise tumour cells bearing a conformational p53 mutant

Autor: Robert C. Rees, KA Mulcahy, AK Murray, CA McIntyre, Stephanie E. B. McArdle, Jeanine Saba

Publikováno v: Cancer Immunology, Immunotherapy. 49:417-425

The tumour-suppressor gene p53 is pivotal in the regulation of apoptosis, and point mutations within p53 are the commonest genetic alterations in human cancers. Cytotoxic T lymphocytes (CTL) recognise peptide-MHC complexes on the surface of tumour ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8066a1c0de0775c2378de3e9c103778
https://doi.org/10.1007/s002620000137

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