Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeanine M. L. Roodhart"'
Autor:
Astrid Kramer, Marjolein J. E. Greuter, Suzanna J. Schraa, Geraldine R. Vink, Jillian Phallen, Victor E. Velculescu, Gerrit A. Meijer, Daan van den Broek, Miriam Koopman, Jeanine M. L. Roodhart, Remond J. A. Fijneman, Valesca P. Retèl, Veerle M. H. Coupé
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Current patient selection for adjuvant chemotherapy (ACT) after curative surgery for stage II colon cancer (CC) is suboptimal, causing overtreatment of high-risk patients and undertreatment of low-risk patients. Postoperative circulating
Externí odkaz:
https://doaj.org/article/df477bb60b4f45289ac535ad731952c5
Autor:
Koen Zwart, Frederieke H. van derBaan, Romain Cohen, Thomas Aparicio, Christelle de laFouchardiére, Thierry Lecomte, Cornelis J. A. Punt, David Sefrioui, Rik J. Verheijden, Geraldine R. Vink, G. Emerens Wensink, Aziz Zaanan, Miriam Koopman, David Tougeron, Jeanine M. L. Roodhart
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 15841-15853 (2023)
Abstract Background Current knowledge on prognostic biomarkers (especially BRAFV600E/RAS mutations) in metastatic colorectal cancer (mCRC) is mainly based on mCRC patients with proficient mismatch repair (pMMR) tumors. It is uncertain whether these b
Externí odkaz:
https://doaj.org/article/78172ed8afd94d10ab4cb901ea49fe41
Autor:
Niek A. Peters, Alexander Constantinides, Inge Ubink, Joyce van Kuik, Haiko J. Bloemendal, Joyce M. van Dodewaard, Menno A. Brink, Thijs P. Schwartz, Martijn P.J.K. Lolkema, Miangela M. Lacle, Leon M. Moons, Joost Geesing, Wilhelmina M.U. van Grevenstein, Jeanine M. L. Roodhart, Miriam Koopman, Sjoerd G. Elias, Inne H.M. Borel Rinkes, Onno Kranenburg
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMesenchymal Consensus Molecular Subtype 4 (CMS4) colon cancer is associated with poor prognosis and therapy resistance. In this proof-of-concept study, we assessed whether a rationally chosen drug could mitigate the distinguishing molecular
Externí odkaz:
https://doaj.org/article/aa2ea800e7be4277afea3b34814f26b9
Autor:
G. Emerens Wensink, Sjoerd G. Elias, Jasper Mullenders, Miriam Koopman, Sylvia F. Boj, Onno W. Kranenburg, Jeanine M. L. Roodhart
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
Abstract Effective predictive biomarkers are needed to enable personalized medicine and increase treatment efficacy and survival for cancer patients, thereby reducing toxic side effects and treatment costs. Patient-derived organoids (PDOs) enable ind
Externí odkaz:
https://doaj.org/article/a906c370b5b841c9aa3ec56321dcb9ce
Autor:
Jeroen W. G. Derksen, Geraldine R. Vink, Marloes A. G. Elferink, Jeanine M. L. Roodhart, Helena M. Verkooijen, Wilhelmina M. U. van Grevenstein, Peter D. Siersema, Anne M. May, Miriam Koopman, The PLCRC Study Group
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Real-world data (RWD) sources are important to advance clinical oncology research and evaluate treatments in daily practice. Since 2013, the Prospective Dutch Colorectal Cancer (PLCRC) cohort, linked to the Netherlands Cancer Registry, serve
Externí odkaz:
https://doaj.org/article/179162c857894da7b1109e3921ce2513
Autor:
G E Wensink, Karen Bolhuis, Marloes A G Elferink, Remond J A Fijneman, Onno Kranenburg, Inne H M Borel Rinkes, Miriam Koopman, Rutger-Jan Swijnenburg, Geraldine R Vink, Jeroen Hagendoorn, Cornelis J A Punt, Jeanine M L Roodhart, Sjoerd G Elias
Publikováno v:
The British journal of surgery, 110(3), 362-371. John Wiley and Sons Ltd
BackgroundPatients who develop early extrahepatic recurrence (EHR) may not benefit from local treatment of colorectal liver metastases (CRLMs). This study aimed to develop a prediction model for early EHR after local treatment of CRLMs using a nation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f4de938dbebf88c099d8b3676ae39d
https://doi.org/10.1093/bjs/znac461
https://doi.org/10.1093/bjs/znac461
Autor:
Marinde J. G. Bond, Patricia A. H. Hamers, Geraldine R. Vink, Wilhelmina M. U. van Grevenstein, Miangela M. Laclé, Maarten van Smeden, Miriam Koopman, Jeanine M. L. Roodhart, Cornelis J. A. Punt, Anne M. May
Publikováno v:
Acta Oncologica, 61(5), 560-565. Informa Healthcare
Introduction: The Memorial Sloan Kettering Cancer Centre (MSKCC) nomogram has been developed to estimate five-year overall survival (OS) after curative-intent surgery of colon cancer based on age, sex, T stage, differentiation grade, number of positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124316eff43f63d8a53d95ce1b817035
https://doi.org/10.1080/0284186x.2022.2044514
https://doi.org/10.1080/0284186x.2022.2044514
Autor:
Hidde R Zuidhof, Martijn van Schelt, Jeanine M L Roodhart, Maarten J ten Berg, Hans Kemperman
Publikováno v:
Clinical Chemistry. 69:540-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86c649ab2f1df4d6b2646ab81169181
https://doi.org/10.1093/clinchem/hvac219
https://doi.org/10.1093/clinchem/hvac219
Autor:
Patricia A. H. Hamers, G. Emerens Wensink, Maarten van Smeden, Geraldine R. Vink, Lidwien P. Smabers, Renee A. Lunenberg, Miangela M. Laclé, Miriam Koopman, Anne M. May, Jeanine M. L. Roodhart
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5094
Background: Predicting prognosis in refractory metastatic colorectal cancer (mCRC) patients is needed to guide decision making. The Colon Life nomogram was developed to predict 12-week mortality in refractory mCRC patients. The aim of this study is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd71f76d368e2c5a207248da611eb04b
Autor:
Karen Bolhuis, G. Emerens Wensink, Marloes A. G. Elferink, Marinde J. G. Bond, Willemieke P. M. Dijksterhuis, Remond J. A. Fijneman, Onno W. Kranenburg, Inne H. M. Borel Rinkes, Miriam Koopman, Rutger-Jan Swijnenburg, Geraldine R. Vink, Jeroen Hagendoorn, Cornelis J. A. Punt, Sjoerd G. Elias, Jeanine M. L. Roodhart
Publikováno v:
Cancers, 14(10):2356. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers; Volume 14; Issue 10; Pages: 2356
Bolhuis, K, Wensink, G E, Elferink, M A G, Bond, M J G, Dijksterhuis, W P M, Fijneman, R J A, Kranenburg, O W, Borel Rinkes, I H M, Koopman, M, Swijnenburg, R-J, Vink, G R, Hagendoorn, J, Punt, C J A, Elias, S G & Roodhart, J M L 2022, ' External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort ', Cancers, vol. 14, no. 10, 2356 . https://doi.org/10.3390/cancers14102356
Cancers; Volume 14; Issue 10; Pages: 2356
Bolhuis, K, Wensink, G E, Elferink, M A G, Bond, M J G, Dijksterhuis, W P M, Fijneman, R J A, Kranenburg, O W, Borel Rinkes, I H M, Koopman, M, Swijnenburg, R-J, Vink, G R, Hagendoorn, J, Punt, C J A, Elias, S G & Roodhart, J M L 2022, ' External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort ', Cancers, vol. 14, no. 10, 2356 . https://doi.org/10.3390/cancers14102356
Optimized surgical techniques and systemic therapy have increased the number of patients with colorectal liver metastases (CRLM) eligible for local treatment. To increase postoperative survival, we need to stratify patients to customize therapy. Most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225588cd10728cbf2c9092a51108eb57
https://doi.org/10.3390/cancers14102356
https://doi.org/10.3390/cancers14102356