Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jeanine Baisch"'
Autor:
Jacqueline S. Gofshteyn, Leanne Mansfield, Jacob Spitznagle, Preetha Balasubramanian, Jacob Cardenas, Thomas Miller, Jinghua Gu, Xuan Wang, Marilynn Punaro, Julie Fuller, Lorien Nassi, Katie Stewart, Marina Ohouo, Cristy Stagnar, Jeanine Baisch, Lynnette Walters, Yuanyuan Wang, Helena Yan, Darawan Rinchai, Damien Chaussabel, Simone Caielli, Seunghee Hong, Karen Onel, Tracey Wright, Virginia Pascual
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1488ce2746648cc87fb89086ee6084ba
https://doi.org/10.1002/art.42446
https://doi.org/10.1002/art.42446
Autor:
Simone Caielli, Jean-Philippe Blanck, Raphaela Goldbach-Mansky, Julie Fuller, Virginia Pascual, Tracey Wright, Jacques Banchereau, Jeanine Baisch, Katie Stewart, Seunghee Hong, Lorien Nassi, Preetha Balasubramanian, Lynnette Walters, Jinghua Gu, Marina Ohouo, Jacob Cardenas, Cristy Stagnar, Adriana Almeida de Jesus
Publikováno v:
Cell
Nat Immunol
Nat Immunol
Emerging evidence supports that mitochondrial dysfunction contributes to Systemic Lupus Erythematosus (SLE) pathogenesis. Here we show that programmed mitochondrial removal, a hallmark of mammalian erythropoiesis, is defective in SLE. Specifically, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f21a807a857a1761a57a68c92ebfdf
https://europepmc.org/articles/PMC8380737/
https://europepmc.org/articles/PMC8380737/
Autor:
Alma-Martina Cepika, Allen D. Sawitzke, Seunghee Hong, Marta M. Guerra, Jill P. Buyon, Joan T. Merrill, Bat Sheva L. Maslow, Marina Ohouo, Derek Blankenship, Djamel Nehar-Belaid, Virginia Pascual, Michelle Petri, Gerlinde Obermoser, Jane E. Salmon, Jacques Banchereau, Jeanine Baisch, John Nulsen, D. Ware Branch, Romain Banchereau, Lisa R. Sammaritano, Tae Whan Kim, Jacob Cardenas, Carl A. Laskin, Esperanza Anguiano, Elizabeth Gatewood, T. Flint Porter, Jacob Turner
Publikováno v:
The Journal of Experimental Medicine
Healthy and uncomplicated lupus pregnancies exhibit early and sustained transcriptional modulation of lupus-related pathways. This might contribute to fetal tolerance while predisposing pregnant women to certain infections. Failure to modulate these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55a67da208d1d5f28b453fcb0d8e4a7
http://europepmc.org/articles/PMC6504211
http://europepmc.org/articles/PMC6504211
Autor:
Richie P. Huynh, Anna Lisa Lucido, Robert J. Rossi, Virginia Pascual, Paul Robson, William F. Flynn, Guo Chen, Tracey Wright, Octavio Ramilo, Prashant Singh, Joy Ann Tabanor-Gayle, Seunghee Hong, Mohan Bolisetty, Jacques Banchereau, Jeanine Baisch, Marilynn Punaro, Cheng-han Chung, Radu Marches, Djamel Nehar-Belaid, Asuncion Mejias, Karolina Palucka, Magalie A. Collet, Navya Kuchipudi, Santhanam Lakshminarayanan, Lynnette Walters
Publikováno v:
Nature immunology
Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome whose cellular origin is poorly resolved. Using single-cell RNA sequencing, we profiled ~276,000 peripheral blood mononuclear cells from 33 children with SLE with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1cbadaaf6e9c86e8e7aa7cad732528
https://pubmed.ncbi.nlm.nih.gov/32747814
https://pubmed.ncbi.nlm.nih.gov/32747814
Autor:
Manjari Chandra, Bojana Domic, Virginia Pascual, Simone Caielli, Lorien Nassi, Cheng-han Chung, Preetha Balasubramanian, Hideki Ueno, Romain Banchereau, Shruti Athale, Julie Fuller, Joseph X. Zhou, Zhaohui Xu, Elise Murat, Tracey Wright, Marilynn Punaro, Diogo Troggian Veiga, Jacques Banchereau, Jeanine Baisch, Duygu Ucar, Katie Stewart, Lynnette Walters
Publikováno v:
Nature Medicine. 25:75-81
Understanding the mechanisms underlying autoantibody development will accelerate therapeutic target identification in autoimmune diseases such as systemic lupus erythematosus (SLE)1. Follicular helper T cells (TFH cells) have long been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb53836ba623077f89f40f6fd4aa1f8e
https://doi.org/10.1038/s41591-018-0254-9
https://doi.org/10.1038/s41591-018-0254-9
Autor:
Tracey Wright, Simone Caielli, Marina Ohouo, Cindy M Wang, Karen Onel, Seunghee Hong, Yuanyuan Wang, Jeanine Baisch, Virginia Pascual, Natalie Rosenwasser, Peter R. Oxley, Phuong Duc Nguyen, Cynthia Smitherman, Lynnette Walters
Publikováno v:
Poster Presentations.
Background: Children with systemic lupus erythematosus (cSLE) with kidney involvement face considerable morbidity and mortality. Commonly used methods for assessing kidney involvement in cSLE, such as renal function tests, are non-specific and provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041ef67654bbfaf74700950ee1eaf943
https://doi.org/10.1136/annrheumdis-2019-eular.5241
https://doi.org/10.1136/annrheumdis-2019-eular.5241
Autor:
Miho Nakajima, Maša Alečković, Linda Bojmar, Avigdor Scherz, Benjamin A. Garcia, Jacqueline Bromberg, Irit Sagi, Pernille Lauritzen, Yuan Liu, Michael F. Berger, Kayleen A. Bailey, Kofi Ennu Gyan, Moshe Oren, Kei Sugiura, Charles M. Rudin, Zoe Posner, Shakeel Modak, Milica Tesic Mark, Joshua S. Jolissant, Irina Matei, Henrik Molina, Constantinos P. Zambirinis, Mark A. LaBarge, G. Praveen Raju, Srikanth R. Ambati, Jeanine Baisch, Mariel Marrano, Tanya M. Trippett, Caitlin Williams, Alexander J. Chou, Ayako Hashimoto, David J. Pisapia, Michele Cioffi, Stephanie Vitolano, Norman J. Lacayo, Yves A. DeClerck, Geraldine P. Wright, Michael A. Hollingsworth, Joe DeStefano, Vinod P. Balachandran, Michael H.A. Roehrl, Mary Petriccione, Mary S. Brady, Kim Kramer, Héctor Peinado, Guillermo García-Santos, David R. Jones, Haiying Zhang, Mina J. Bissell, Jonathan M. Hernandez, Naoko Takahashi, Yonathan Ararso, L. Miles Schaeffer, Daniela Freitas, Enrico Danzer, David P. Kelsen, Ben Z. Stanger, Paul A. Meyers, Stephen S. Roberts, Cyrus M. Ghajar, Angela Di Giannatale, Jack D. Bui, William R. Jarnagin, Virginia Pascual, Eileen M. O'Reilly, Todd E. Heaton, David Lyden, Amber L. Simpson, Michael P. La Quaglia, Arti Shukla, Serena Lucotti, Vinagolu K. Rajasekhar, Amina Ahmed, John H. Healey, Robert E. Schwartz, Candia M. Kenific, Emily K. Slotkin, Laura Nogués, Kristy A. Brown, Søren Heissel, Daniel Diolaiti, Loïc Steiner, Ruth Scherz-Shouval, Yosef Yarden, Theresa C. Vincent, Martin R. Weiser, Fatima Cardoso, Han Sang Kim, Ayuko Hoshino, Huajuan Wang, Sujit Sheth, Fanny A. Pelissier Vatter, Yibin Kang, Maria Donzelli, Laurence Blavier, Benjamin A. Krantz, Alexander E. Davies, Thomas C. Caffrey, Yusuke Ogitani, Cheryl Fischer, Maria de Sousa, Gonçalo Rodrigues, Ellen M. Basu, Weston Buehring, Surinder K. Batra, Maneesh Jain, Diane M. Simeone, Leonard H. Wexler, Alberto Benito-Martin, Yasmin Khakoo, Lee Ganshaw, Katharine Offer, Paul M. Grandgenett, Bruno Costa-Silva, Kevin C. De Braganca, Mahathi Malladi, Ashton Harris
Publikováno v:
Signal Transduction and Targeted Therapy
Cell
Cell
Summary There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in 426 human samples from tissue explants (TEs), plasma, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153110f98011152e4a3cfc2673431c6d
https://doi.org/10.1016/j.cell.2020.07.009
https://doi.org/10.1016/j.cell.2020.07.009
Autor:
Michelle Edens, Marilynn Punaro, Jose Rossello-Urgell, Jacob Turner, Shaheen Khan, Derek Blankenship, Alisa Gotte, Gerlinde Obermoser, Lorien Nassi, Jacques Banchereau, Jeanine Baisch, Brandi L. Cantarel, Nicole Baldwin, Romain Banchereau, Seunghee Hong, Parvathi Vinod, Esperanza Anguiano, Yong-Jun Liu, Virginia Pascual, Edward K. Wakeland, Alma-Martina Cepika, Tracey Wright, Peter Acs
Publikováno v:
Cell. 165:1548-1550
Summary Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of tolerance to nucleic acids and highly diverse clinical manifestations. To assess its molecular heterogeneity, we longitudinally profiled the blood transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0db57b0b463414a9e557b51724b0f6
https://doi.org/10.1016/j.cell.2016.05.057
https://doi.org/10.1016/j.cell.2016.05.057
Autor:
Mark M. Davis, Damien Chaussabel, David A. Hafler, Susan M. Kaech, Jacob Frelinger, Yuri Kotliarov, Damian Fermin, Evan Henrich, Raphael Gottardo, A. Karolina Palucka, Albert C. Shaw, Purvesh Khatri, Ruth R. Montgomery, Kenneth Stuart, Jean H. Wilson, John S. Tsang, Robert B. Belshe, Heidi J Zapata, Nicole Baldwin, Subhasis Mohanty, Renaud Gaujoux, Samit R Joshi, Ellis L. Reinherz, Barbara Siconolfi, G.A. Poland, Renan Sauteraud, Jeanine Baisch, Diane E. Grill, Bali Pulendran, Hailong Meng, Richard B. Kennedy, Gerlinde Obermoser, Virginia Pascual, Ikuyo Ueda, Esperanza Anguiano, Tamara P. Blevins, Ann L. Oberg, Erol Fikrig, Steven H. Kleinstein, Foo Cheung, Stefan Avey, Sui Tsang, Francesco Vallania, Inna G. Ovsyannikova, Shai S. Shen-Orr
Publikováno v:
Science Immunology. 2
Annual influenza vaccinations are currently recommended for all individuals 6 months and older. Antibodies induced by vaccination are an important mechanism of protection against infection. Despite the overall public health success of influenza vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fec28fc36a5a63470a37c2de2b593d
https://doi.org/10.1126/sciimmunol.aal4656
https://doi.org/10.1126/sciimmunol.aal4656
Autor:
Jacques Banchereau, Jeanine Baisch, Elise Murat, Marilynn Punaro, Sandra Clayton, Shruti Athale, Cristiana Guiducci, Romain Banchereau, Karolina Palucka, Kate Phelps, Simone Caielli, Tracey Wright, Bojana Domic, Virginia Pascual, Manjari Chandra, Mei Gong
Publikováno v:
The Journal of experimental medicine. 213(5)
Autoantibodies against nucleic acids and excessive type I interferon (IFN) are hallmarks of human systemic lupus erythematosus (SLE). We previously reported that SLE neutrophils exposed to TLR7 agonist autoantibodies release interferogenic DNA, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b683600319a378af11d15ec0cefe1906
https://pubmed.ncbi.nlm.nih.gov/30532021
https://pubmed.ncbi.nlm.nih.gov/30532021