Výsledky vyhledávání - "Jeanifer Gachev"

COVID‐19 infection in patients on anti‐complement therapy: The Leeds National Paroxysmal Nocturnal Haemoglobinuria service experience

Autor: Petra Muus, Nicola Houghton, Lindsay Mitchell, Jeanifer Gachev, Kathryn Riley, Louise Arnold, Alexandra Pike, Morag Griffin, Tahla Munir, Peter Hillmen, Briony Forrest

Publikováno v: British Journal of Haematology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748f17311dad86f9ed1c3781da652d49
http://europepmc.org/articles/PMC7537165

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Management of Meningococcal Disease Risk in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) on Complement Inhibitors: 18 Years' Experience from the UK National PNH Service in Leeds

Autor: Morag Griffin, Rachael Jones, Louise Arnold, Jeanifer Gachev, Kathryn Riley, Petra Muus, Briony Forrest, Peter Hillmen, Talha Munir, Alexandra Pike, Ray Borrow, Richard Kelly

Publikováno v: Blood. 136:5-6

Eculizumab, the monoclonal antibody targeting C5, is the only licensed treatment for Paroxysmal Nocturnal Hemoglobinuria (PNH) in the UK. Inherent to the mechanism of action, C5 inhibitors increase patient susceptibility to encapsulated microorganism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a09705e7142696d03979bed07f33f6c9
https://doi.org/10.1182/blood-2020-141780

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Thrombotic Events with Neisseria Meningitidis Vaccination in Patients with Paroxysmal Nocturnal Hemoglobinuria, UK Experience

Autor: Briony Forrest, Peter Hillmen, Kathryn Riley, Jeanifer Gachev, Petra Muus, Morag Griffin, Alexandra Pike, Talha Munir, Richard Kelly, Louise Arnold

Publikováno v: Blood. 136:35-36

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hemolytic and thrombotic condition. Patients can experience severe anemia due to intravascular hemolysis, thrombotic events, renal impairment and pulmonary hypertension. Symptomatic patients are tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c63c29dd5c69e569fcc531f89f80d04
https://doi.org/10.1182/blood-2020-141769

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Incomplete Complement Inhibition in Patients with PNH on Eculizumab - 5 Year Experience from the National PNH Service Leeds

Autor: Rachael Jones, Talha Munir, Alexandra Pike, Petra Muus, Louise Arnold, Morag Griffin, Peter Hillmen, Jeanifer Gachev, Briony Forrest

Publikováno v: Blood. 136:8-9

Background Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare acquired disorder characterised by intravascular hemolysis and thrombosis. Patients with symptomatic PNH are commenced on the complement inhibitor eculizumab (600mg weekly for 5 weeks the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a14dd5bc451e90c02ee016220be4b14
https://doi.org/10.1182/blood-2020-140256

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