Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeanette Teague"'
Autor:
Leslie S. Satin, David H. Wasserman, Jeanette Teague, Craig S. Nunemaker, Owen P. McGuinness, Ian R. Sweet
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 290:E523-E529
Islets in most species respond to increased glucose with biphasic insulin secretion, marked by a sharp first-phase peak and a slowly rising second phase. Mouse islets in vitro, however, lack a robust second phase. To date, this observation has not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8602f35282761ab7032b998a058101ed
https://doi.org/10.1152/ajpendo.00392.2005
https://doi.org/10.1152/ajpendo.00392.2005
Autor:
Leslie S. Satin, Mary E. Abood, Jeanette Teague, Paulette B. Goforth, Qing Tao, Tracie A. Kinard
Publikováno v:
Diabetes. 50:992-1003
Insulin-secreting pancreatic islet beta-cells possess anion-permeable Cl- channels (I(Cl,islet)) that are swelling-activated, but the role of these channels in the cells is unclear. The Cl- channel blockers 4,4'-diisothiocyanostilbene-2,2'-disulfonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cef8caa8332626e5dd12ea667f93a16
https://doi.org/10.2337/diabetes.50.5.992
https://doi.org/10.2337/diabetes.50.5.992
Autor:
Thomas N. Wight, Sofianos Andrikopoulos, Jeanette Teague, Steven E. Kahn, Wilfred Y. Fujimoto, C. B. Verchere, W M Howell
Publikováno v:
Diabetes. 48:1962-1970
Type 2 diabetes is characterized by islet amyloid deposits, which are primarily composed of the amyloidogenic human form of islet amyloid polypeptide (IAPP, amylin). The mechanism of islet amyloido-genesis is not known, but other products (e.g., apol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcf1020a47e00d3cfb287484f9cca4d
https://doi.org/10.2337/diabetes.48.10.1962
https://doi.org/10.2337/diabetes.48.10.1962
Publikováno v:
Proceedings of the National Academy of Sciences. 94:3223-3228
Both insulin and insulin-like growth factor 1 (IGF-1) are known to reduce glucose-dependent insulin secretion from the β cells of pancreatic islets. In this paper we show that the mechanism by which IGF-1 mediates this effect is in large part throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3a6670a634407cc15821d3478d7188
https://doi.org/10.1073/pnas.94.7.3223
https://doi.org/10.1073/pnas.94.7.3223
Autor:
Jeanette Teague, William Hagopian, Åke Lernmark, Jianjie Jiang, Jacob S. Petersen, Allan E. Karlsen, Ana L. Gervassi, Wilfred Y. Fujimoto
Publikováno v:
Endocrinology. 132:2674-2681
Macaca nemestrina, which may have larger and more numerous pancreatic islets than other species, was used for large scale islet isolation by ductal collagenase perfusion and Ficoll gradient centrifugation. The average yield was 51,000 islet equivalen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9118b84c92964b3467b9a77d524f16bf
https://doi.org/10.1210/endo.132.6.8504767
https://doi.org/10.1210/endo.132.6.8504767
Autor:
Steven E. Kahn, Christina Tsoi, Jeanette Teague, Kathleen R. Braun, Rebecca L. Hull, Thomas N. Wight, Susan Potter-Perigo, C. Bruce Verchere, Sofianos Andrikopoulos
Publikováno v:
Archives of biochemistry and biophysics. 413(2)
Pancreatic islet amyloid deposits in type 2 diabetes are associated with decreased islet beta-cell function. They contain both amylin (islet amyloid polypeptide), the beta-cell-derived unique fibrillogenic component, and heparan sulfate proteoglycans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d0f1d34109643b33afd2ab8d5ba5fc
https://pubmed.ncbi.nlm.nih.gov/12729615
https://pubmed.ncbi.nlm.nih.gov/12729615
Autor:
Daniel L. Cook, Jeanette Teague, Robert W. Wiseman, Kenneth A. Krohn, Åke Lernmark, Ian R. Sweet, Carla J. Greenbaum, Shinichi Matsumoto
Publikováno v:
Diabetes technologytherapeutics. 4(1)
Advances in human islet transplant techniques are hampered by the inability to assess the quality of isolated islets. A flow culture system was developed to perifuse isolated pancreatic islets or cultured beta-cell lines in order to continuously and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296d5b13de4504cf0d7afb3ec12bdd77
https://pubmed.ncbi.nlm.nih.gov/12017423
https://pubmed.ncbi.nlm.nih.gov/12017423
Publikováno v:
Endocrinology. 136(10)
The pharmacological properties of voltage-gated Ca current and glucose-dependent insulin secretion were determined using the HIT insulinoma line to understand the role of Ca channels in stimulus-secretion coupling. The L-type Ca channel antagonist ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb921fe01e5b466b9c896f542b2b674
https://pubmed.ncbi.nlm.nih.gov/7545106
https://pubmed.ncbi.nlm.nih.gov/7545106
Autor:
Jeanette Teague, Wilfred Y. Fujimoto
Publikováno v:
Diabetes. 38:625-628
Monolayer cultures of HIT cells were superfused to examine phasic insulin secretion. A Diphasic pattern of insulin secretion was observed when cells were stimulated with a constant glucose concentration as low as 0.28 mM, with increasing stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd205892997ea1e939fd800ed265c3e8
https://doi.org/10.2337/diab.38.5.625
https://doi.org/10.2337/diab.38.5.625
Publikováno v:
In Vitro. 13:237-244
We have developed a simple technique for the investigation of cellular metabolism and growth in cultured human fibroblasts which facilitates experiments using up to 3 x 10(5) cells in each of 100 or more culture vessels. The method has been used to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea985d9e4485826938e479e98d909bf6
https://doi.org/10.1007/bf02615081
https://doi.org/10.1007/bf02615081