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The psychotropic drug olanzapine (Zyprexa) increases the area of acid glycerophospholipid monolayers
Autor:
Jeanette Pfeiffer, Synnøve Thoresen, Anja Underhaug Gjerde, Holm Holmsen, Hanne Linn Gjerde, Signe Steinkopf, Anja Katrin Schelderup
Publikováno v:
Biophysical chemistry. 134(1-2)
The typical antipsychotics chlorpromazine (CPZ) and trifluoperazine (TFP) increase the mean molecular area (mma) of acidic, but not neutral, glycerophospholipids in monolayers at pH 7.36 measured by the Langmuir technique. The atypical antipsychotic