Výsledky vyhledávání - "Jeanette P. Brown"

Autor: Jeanette P. Brown

Publikováno v: Sleep Medicine Clinics. 15:593-598

The number of patients experiencing prolonged mechanical ventilation is increasing over time. Patients who have a tracheostomy placed in a critical care setting have been described as having an average of 4 separate transitions between the acute care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c237191f4c5ad94b842508db9478d102
https://doi.org/10.1016/j.jsmc.2020.08.003

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Transition Care for Adolescents and Young Adults with Neuromuscular Disease and Chronic Pulmonary Care Needs

Autor: Kathleen S. Irby, Jeanette P. Brown

Publikováno v: Transitioning Care from Pediatric to Adult Pulmonology ISBN: 9783030686871

The care of adolescents and young adults with neuromuscular disease and chronic pulmonary care needs is an involved and complex experience for providers, patients, and families. This population is best served by a multidisciplinary team model, if at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59f4f0f60978b82c10734509af4faea6
https://doi.org/10.1007/978-3-030-68688-8_8

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Positive airway pressure therapy for sleep-disordered breathing confers short-term benefits to patients with spinal cord injury despite widely ranging patterns of use

Autor: Helena Schotland, Robert G. Sitrin, Armando Kurili, Jeanette P. Brown, Gianna M. Rodriguez, Anthony Chiodo, Kristy A. Bauman

Publikováno v: Spinal Cord. 56:777-789

Prospective, cohort study. To evaluate the effectiveness of bi-level positive airway pressure (PAP) therapy and the patterns of use for sleep-disordered breathing (SDB) in individuals with spinal cord injury (SCI). Academic tertiary care center, USA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d14603e18e3a980aed71320df693824
https://doi.org/10.1038/s41393-018-0077-z

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Chronic obstructive pulmonary disease comorbidities

Autor: Jeanette P. Brown, Carlos H. Martinez

Publikováno v: Current opinion in pulmonary medicine. 22(2)

Classic descriptions of chronic obstructive pulmonary disease (COPD) centered on its impact on respiratory function. It is currently recognized that comorbidities contribute to the severity of symptoms and COPD progression. Understanding COPD-comorbi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beac2e5dc24403565be8b9ae512fc449
https://pubmed.ncbi.nlm.nih.gov/26814720

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Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

Autor: Patricia V. Basta, Annette T. Hastie, Stephen I. Rennard, Robert Paine, Neil E. Alexis, David Couper, Jeffrey L. Curtis, Robert J. Kaner, Elizabeth E. Carretta, Valerie R. Stolberg, Daichi Shimbo, Wanda K. O'Neal, Claire M. Doerschuk, Jeanette P. Brown, Christine M. Freeman, Prescott G. Woodruff, Joanne Sonstein, Sean Crudgington, Michelle Zeidler

Publikováno v: Journal of Translational Medicine

Background: Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) is a multi-center longitudinal, observational study to identify novel phenotypes and biomarkers of chronic obstructive pulmonary disease (COPD). In a subset of 300 subject

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Toll-Like Receptor 2 Plays a Pivotal Role in Host Defense and Inflammatory Response to Borrelia burgdorferi

Autor: Ying Ma, John H. Weis, Jeanette P. Brown, R. Mark Wooten, Carsten J. Kirschning, Janis J. Weis, Alyson Yoder, James F. Zachary

Publikováno v: Vector-Borne and Zoonotic Diseases. 2:275-278

275 BORRELIA BURGDORFERI infection of humans is a multisystem illness characterized by persistent bacterial infection and invasion of numerous tissues (Steere 2001). Arthritis can result from spirochete invasion of joint tissue, and is characterized

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https://doi.org/10.1089/153036602321653860

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Toll-Like Receptor 2 Is Required for Innate, But Not Acquired, Host Defense to Borrelia burgdorferi

Autor: James F. Zachary, Janis J. Weis, Alyson Yoder, R. Mark Wooten, Ying Ma, Carsten J. Kirschning, John H. Weis, Jeanette P. Brown

Publikováno v: The Journal of Immunology. 168:348-355

Borrelia burgdorferi lipoproteins activate inflammatory cells through Toll-like receptor 2 (TLR2), suggesting that TLR2 could play a pivotal role in the host response to B. burgdorferi. TLR2 does play a critical role in host defense, as infected TLR2

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https://doi.org/10.4049/jimmunol.168.1.348

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Transforming growth factor-β induces microRNA-29b to promote murine alveolar macrophage dysfunction after bone marrow transplantation

Autor: Jeanette P. Brown, Yasmina Laouar, Gregory A. Yanik, Christine M. Freeman, Racquel Domingo-Gonzalez, Steven K. Huang, Carol A. Wilke, Jeffrey L. Curtis, Bethany B. Moore

Hematopoietic stem cell transplantation (HSCT) is complicated by pulmonary infections that manifest posttransplantation. Despite engraftment, susceptibility to infections persists long after reconstitution. Previous work using a murine bone marrow tr

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https://europepmc.org/articles/PMC4281703/

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Glucocorticoid-Augmented Efferocytosis Inhibits Pulmonary Pneumococcal Clearance in Mice by Reducing Alveolar Macrophage Bactericidal Function

Autor: Jeffrey L. Curtis, Bridget L. Saxton, Alexandra L. McCubbrey, Sophina H. Taitano, Christine M. Freeman, Peter Mancuso, Jeanette P. Brown, Valerie R. Stolberg, Sean Crudgington

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 195(1)

Inhaled corticosteroids (ICS) increase community-acquired pneumonia (CAP) incidence in patients with chronic obstructive pulmonary disease (COPD) by unknown mechanisms. Apoptosis is increased in the lungs of COPD patients. Uptake of apoptotic cells (

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https://pubmed.ncbi.nlm.nih.gov/25987742

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Dual Role of Interleukin-10 in Murine Lyme Disease: Regulation of Arthritis Severity and Host Defense

Autor: Cory Teuscher, Jeanette P. Brown, Janis J. Weis, James F. Zachary, R. Mark Wooten

Publikováno v: Infection and Immunity. 67:5142-5150

In the murine model of Lyme disease, C3H/He mice exhibit severe arthritis while C57BL/6N mice exhibit mild lesions when infected with Borrelia burgdorferi . Joint tissues from these two strains of mice harbor similar concentrations of B. burgdorferi

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https://doi.org/10.1128/iai.67.10.5142-5150.1999

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