Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Jeanette L.C. Miller"'
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Akademický článek
Fibrin and D-dimer bind to monomeric GPVI
Autor: Marie-Blanche Onselaer, Alexander T. Hardy, Clare Wilson, Ximena Sanchez, Amir K. Babar, Jeanette L.C. Miller, Callum N. Watson, Stephanie K. Watson, Arkadiusz Bonna, Helen Philippou, Andrew B. Herr, Diego Mezzano, Robert A.S. Ariëns, Steve P. Watson
Publikováno v: Blood Advances, Vol 1, Iss 19, Pp 1495-1504 (2017)
Abstract: Fibrin has recently been shown to activate platelets through the immunoglobulin receptor glycoprotein VI (GPVI). In the present study, we show that spreading of human platelets on fibrin is abolished in patients deficient in GPVI, confirmin
Externí odkaz: https://doaj.org/article/1f1cbed05f4449a0b9bb085f298bf5e5
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2
Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I
Autor: David A. Yeung, Ramesh K. Ganju, Carolyn Wang, Brent A. Weiss, Subhadip Das, Anjum Sohail, Andrew B. Herr, Nirvan Shanker, Jeanette L.C. Miller, Jack Wellmerling, Gunjan Agarwal, Rafael Fridman
Publikováno v: Journal of Molecular Biology. 431:368-390
Discoidin domain receptors (DDR1 and DDR2) are receptor tyrosine kinases that signal in response to collagen. We had previously shown that collagen binding leads to clustering of DDR1b, a process partly mediated by its extracellular domain (ECD). In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdf371d97153d3ae458e6d2493afc51
https://doi.org/10.1016/j.jmb.2018.11.015
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4
Structural basis for collagen recognition by the immune receptor OSCAR
Autor: Alexander D. Barrow, Dimitri Y. Chirgadze, Michal Blaszczyk, Andrew B. Herr, Deborah G. Conrady, Richard W. Farndale, Long Zhou, Jeanette L.C. Miller, Jennifer M. Hinerman, Dominique Bihan
Publikováno v: Blood. 127:529-537
The osteoclast-associated receptor (OSCAR) is a collagen-binding immune receptor with important roles in dendritic cell maturation and activation of inflammatory monocytes as well as in osteoclastogenesis. The crystal structure of the OSCAR ectodomai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c6675375cd44d92a31a3ea3b42917b5
https://doi.org/10.1182/blood-2015-08-667055
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6
An improved Western blot assay to assess the clearance of prion protein from plasma-derived therapeutic proteins
Autor: Christopher J. Stenland, Stephen R. Petteway, Michèle M. Kislan, Mark S. Nelson, Dominique Pifat, Jeanette L.C. Miller, Randal C. Hartwell, Kang Cai
Publikováno v: Journal of Virological Methods. 125:187-193
Specific detection of the pathogenic prion protein, PrP(Sc), is essential for determining the prion clearance capacity of purification processes for therapeutic proteins. Use of a previously described indirect (two-antibody) Western blot assay someti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35a146a4732b0855131504d47bd61d3
https://doi.org/10.1016/j.jviromet.2005.01.026
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8
Solvent-dependent precipitation of prion protein
Autor: Christopher J. Stenland, Richard Rubenstein, Terry Jarrett C, Rosemary B. Evans-Storms, Douglas C. Lee, Stephen R. Petteway, Kevin J. Gilligan, Jeanette L.C. Miller, Randal C. Hartwell, Kang Cai
Publikováno v: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1597:28-35
The misfolded isoform of the prion protein (PrP(Sc)) possesses many unusual physiochemical properties. Previously, we and others reported on the differential partitioning of PrP(Sc) from plasma derived therapeutic proteins during their purification p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909ee29495cf0a885b2a4f09e904c86e
https://doi.org/10.1016/s0167-4838(02)00282-0
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9
A direct relationship between the partitioning of the pathogenic prion protein and transmissible spongiform encephalopathy infectivity during the purification of plasma proteins
Autor: Michael Fournel, Douglas C. Lee, Stephen R. Petteway, Kevin J. Gilligan, Kang Cai, Terry Jarrett C, Elizabeth K. Ford, Richard Rubenstein, Randal C. Hartwell, Jeanette L.C. Miller, Christopher J. Stenland
Publikováno v: Transfusion. 41:449-455
BACKGROUND: Experimental evidence from rodent models indicates that blood can contain transmissible spongiform encephalopathy (TSE) infectivity, which suggests a potential risk for TSE transmission via proteins isolated from human plasma. Because met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5c128d1a3d100b4d8e7dcd335d3caa
https://doi.org/10.1046/j.1537-2995.2001.41040449.x
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10
Monitoring plasma processing steps with a sensitive Western blot assay for the detection of the prion protein
Autor: Christopher J. Stenland, Elizabeth K. Ford, Michael Fournel, Stephen R. Petteway, Kevin J. Gilligan, Randal C. Hartwell, Richard Rubenstein, Douglas C. Lee, Jeanette L.C. Miller, Kang Cai
Publikováno v: Journal of Virological Methods. 84:77-89
Determining the risk of transmissible spongiform encephalopathy (TSE) transmission by blood or plasma-derived products requires sensitive and specific assays for the detection of either infectivity or a reliable marker for infectivity. To this end, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe33461ba9844fc4b2522b3848be39b
https://doi.org/10.1016/s0166-0934(99)00135-4
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