Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jeanette J. McCarthy"'
Autor:
Ashlee M. Benjamin, Sunil Suchindran, Kaela Pearce, Jennifer Rowell, Lillian F. Lien, John R. Guyton, Jeanette J. McCarthy
Publikováno v:
Journal of Obesity, Vol 2011 (2011)
Obesity is an increasingly prevalent and severe health concern with a substantial heritable component and marked sex differences. We sought to determine if the effect of genetic variants also differed by sex by performing a genome-wide association st
Externí odkaz:
https://doaj.org/article/5a191be189a74684930f183bcc347e16
Publikováno v:
Personalized Medicine. 18:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78e5814a3fa8e839c9e25604313c700
https://doi.org/10.2217/pme-2020-0176
https://doi.org/10.2217/pme-2020-0176
Autor:
Colton Linnertz, Ann M Saunders, Michael W Lutz, Donna M Crenshaw, Iris Grossman, Daniel K Burns, Keith E Whitfield, Michael A Hauser, Jeanette J McCarthy, Megan Ulmer, Rand Allingham, Kathleen A Welsh-Bohmer, Allen D Roses, Ornit Chiba-Falek
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30994 (2012)
We previously discovered that a polymorphic, deoxythymidine-homopolymer (poly-T, rs10524523) in intron 6 of the TOMM40 gene is associated with age-of-onset of Alzheimer's disease and with cognitive performance in elderly. Three allele groups were def
Externí odkaz:
https://doaj.org/article/f942e05d472a4d749d9caeb46a486e20
Publikováno v:
Personalized medicine. 15(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4590b10f0144e5fc38bb6e8428193ae
https://pubmed.ncbi.nlm.nih.gov/29927353
https://pubmed.ncbi.nlm.nih.gov/29927353
Incorporate genomics into every applicable area of your clinical practice with this complete how-to guide Precision Medicine: A Guide to Genomics in Clinical Practice is a comprehensive, yet succinct overview of the practice of genomic medicine. It i
Autor:
Avshalom Caspi, Karen Sugden, Benjamin Williams, Daniel W. Belsky, Renate Houts, Jeanette J. McCarthy, Terrie E. Moffitt
Publikováno v:
Biodemography and Social Biology. 59:85-100
Multi-locus profiles of genetic risk, so-called "genetic risk scores," can be used to translate discoveries from genome-wide association studies into tools for population health research. We developed a genetic risk score for obesity from results of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdd5e7a1dd2c399f40f4415f1e74494
https://doi.org/10.1080/19485565.2013.774628
https://doi.org/10.1080/19485565.2013.774628
Autor:
Leah Kaminsky, Latha Palaniappan, W. Andrew Faucett, Mark J Savant, Robert L. Nussbaum, Helen Messier, Bradley W Popovich, Kenneth B. Beckman, Steven Tucker, Michael J. Dougherty, Michael D. Linderman, Nikki Ledbetter, Elissa Levin, Susan K. Delaney, Cinnamon S. Bloss, Michael F. Christman, David H Haase, Michael L Hultner, Sharon F. Terry, Ondrej Libiger, John Quackenbush, Andy Cosgrove, Howard J. Jacob, John W. Belmont, Stuart A. Heilsberg, Massimo Delledonne, Scott E Megill, Michael M Su, Robert C. Green, Susan L McClure, David Magnus, David H. Ledbetter, Jeanette J. McCarthy, Stephen A. Damiani, William T Wong, Richard L Love, Michael Ball, AnneMarie Martland, Timothy Danis, Jeff Huber, Joel T. Dudley, Warren H Lee, Jennifer Friedman, Thomas S. Hays, Bradley A. Patay
Publikováno v:
Expert review of molecular diagnostics, vol 16, iss 5
Expert Review of Molecular Diagnostics
Expert Review of Molecular Diagnostics
Precision or personalized medicine through clinical genome and exome sequencing has been described by some as a revolution that could transform healthcare delivery, yet it is currently used in only a small fraction of patients, principally for the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec14242b8194bc09be3894638cd855d
http://hdl.handle.net/11562/960626
http://hdl.handle.net/11562/960626
Autor:
Jeanette J. McCarthy
Publikováno v:
Molecular Genetics & Genomic Medicine
I spent most of my career as a genome scientist working on advancing personalized medicine in both academic and industry settings. For years now we have heard about the barriers to implementing personalized medicine and each discussion invariably end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e38decf25c410f50165999fe20f3ef
https://doi.org/10.1002/mgg3.113
https://doi.org/10.1002/mgg3.113
Publikováno v:
Journal of Viral Hepatitis. 18:571-579
Low levels of serum lipids were reported in subjects chronically infected with the hepatitis C virus (HCV) and correlated with poorer clinical outcomes. Whether HCV 'hypo-lipidemia' is constant across age, sex and race has not been systematically exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2955948c8f124bb676ad84edc41357f
https://doi.org/10.1111/j.1365-2893.2010.01347.x
https://doi.org/10.1111/j.1365-2893.2010.01347.x
Autor:
Hans L. Tillmann, Alexander J. Thompson, Keyur Patel, Andrew J. Muir, Xiang Qian Lao, John G. McHutchison, Josephine H. Li, Sunil Suchindran, Jeanette J. McCarthy
Publikováno v:
Gastroenterology. 138:2307-2314
Background & Aims Patients with chronic hepatitis C virus (HCV) infections are treated with pegylated interferon and ribavirin (PEG-IFN/RBV), which is effective in less than 50% of those infected with HCV genotype 1. Genome-wide association studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae04debcafcd3e6b188bbba82a3ef019
https://doi.org/10.1053/j.gastro.2010.02.009
https://doi.org/10.1053/j.gastro.2010.02.009