Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeanette, Rientjes"'
Autor:
Laetitia A. Hughes, Danielle L. Rudler, Stefan J. Siira, Tim McCubbin, Samuel A. Raven, Jasmin M. Browne, Judith A. Ermer, Jeanette Rientjes, Jennifer Rodger, Esteban Marcellin, Oliver Rackham, Aleksandra Filipovska
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The number of tRNA isodecoders has increased dramatically in mammals, but the specific molecular and physiological reasons for this expansion remain elusive. To address this fundamental question we used CRISPR editing to knockout the seven-m
Externí odkaz:
https://doaj.org/article/ec64d6bde2394ea6ac0ddbefcb5e127d
Autor:
Alan Hegron, Chloe J. Peach, Raquel Tonello, Philipp Seemann, Shavonne Teng, Rocco Latorre, Harald Huebner, Dorothee Weikert, Jeanette Rientjes, Nicholas A. Veldhuis, Daniel P. Poole, Dane D. Jensen, Alex R. B. Thomsen, Brian L. Schmidt, Wendy L. Imlach, Peter Gmeiner, Nigel W. Bunnett
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The hypothesis that sustained G protein-coupled receptor (GPCR) signaling from endosomes mediates pain is based on studies with endocytosis inhibitors and lipid-conjugated or nanoparticle-encapsulated antagonists targeted to endosomes. GPCR antagonis
Autor:
Rocco Latorre, Alan Hegron, Chloe J. Peach, Shavonne Teng, Raquel Tonello, Jeffri S. Retamal, Rafael Klein-Cloud, Diana Bok, Dane D. Jensen, Lena Gottesman-Katz, Jeanette Rientjes, Nicholas A. Veldhuis, Daniel P. Poole, Alex R. B. Thomsen, Brian L. Schmidt, Charalabos H. Pothoulakis, Carl Rankin, Ying Xie, Hon Wai Koon, Nigel W. Bunnett
Publikováno v:
Proceedings of the National Academy of Sciences. 119
G protein–coupled receptors (GPCRs) regulate many pathophysiological processes and are major therapeutic targets. The impact of disease on the subcellular distribution and function of GPCRs is poorly understood. We investigated trafficking and sign
Publikováno v:
Journal of Cellular and Molecular Medicine
Duchenne muscular dystrophy is a severe muscle wasting disease caused by mutations in the dystrophin gene (dmd). Ataluren has been approved by the European Medicines Agency for treatment of Duchenne muscular dystrophy. Ataluren has been reported to p
Autor:
Rocco, Latorre, Alan, Hegron, Chloe J, Peach, Shavonne, Teng, Raquel, Tonello, Jeffri S, Retamal, Rafael, Klein-Cloud, Diana, Bok, Dane D, Jensen, Lena, Gottesman-Katz, Jeanette, Rientjes, Nicholas A, Veldhuis, Daniel P, Poole, Brian L, Schmidt, Charalabos H, Pothoulakis, Carl, Rankin, Ying, Xie, Hon Wai, Koon, Nigel W, Bunnett
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(6)
G protein-coupled receptors (GPCRs) regulate many pathophysiological processes and are major therapeutic targets. The impact of disease on the subcellular distribution and function of GPCRs is poorly understood. We investigated trafficking and signal
Autor:
Jeanette Rientjes, Jieqiong Lou, Menachem Gunzburg, Bradley Doak, Jacqueline Norris, Caroline Foley, Sarah N. Dishman, Stephanie Cholensky, Dirk Truman, Emily Kelly, Susan Thomas, Michelle Meilak, Alyce Lynas, Bec Hurley, Fleur Rodda, Casey Grist, Emma Rooney, Tanya Lennane, Leanne Hawkey, Ian Smyth, Kenneth Pearce, Elizabeth Hinde, Lindsey Ingerman James, Stephen Headey
Publikováno v:
SSRN Electronic Journal.