Výsledky vyhledávání - "Jeanesse Scerri"

Akademický článek

PKC-mediated phosphorylation and activation of the MEK/ERK pathway as a mechanism of acquired trastuzumab resistance in HER2-positive breast cancer

Autor: Jeanesse Scerri, Christian Scerri, Felix Schäfer-Ruoff, Simon Fink, Markus Templin, Godfrey Grech

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Protein expression, activation and stability are regulated through inter-connected signal transduction pathways resulting in specific cellular states. This study sought to differentiate between the complex mechanisms of intrinsic and acquired trastuz

Externí odkaz: https://doaj.org/article/88bc182dd81e471287768db22eecb0fc

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Akademický článek

Nanopore Is Preferable over Illumina for 16S Amplicon Sequencing of the Gut Microbiota When Species-Level Taxonomic Classification, Accurate Estimation of Richness, or Focus on Rare Taxa Is Required

Autor: Márton Szoboszlay, Laetitia Schramm, David Pinzauti, Jeanesse Scerri, Anna Sandionigi, Manuele Biazzo

Publikováno v: Microorganisms, Vol 11, Iss 3, p 804 (2023)

Nanopore sequencing is a promising technology used for 16S rRNA gene amplicon sequencing as it can provide full-length 16S reads and has a low up-front cost that allows research groups to set up their own sequencing workflows. To assess whether Nanop

Externí odkaz: https://doaj.org/article/c786fd00bee744529d3a8bec381ee425

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Akademický článek

Prevalence and characteristics of community carriage of methicillin-resistant Staphylococcus aureus in Malta

Autor: Jeanesse Scerri, Stefan Monecke, Michael A. Borg

Publikováno v: Journal of Epidemiology and Global Health, Vol 3, Iss 3 (2019)

Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen worldwide. Malta is one of the countries with the highest MRSA prevalence in Europe, as identified from hospital blood cultures [1]. However, community prevalence of MR

Externí odkaz: https://doaj.org/article/f70eb6b05f314118af3535f335499a7f

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Abstract 12832: Yield From Family Screening in a National Adolescent Cardiac Screening Program

Autor: Mark Abela, Jessica Debattista, Jeanesse Scerri, KENTARO YAMAGATA, Felice Tiziana, Melanie R Zammit Burg, Mark A Sammut, Robert G Xuereb, Victor Grech, Christian Scerri, lorenzo I monserrat, Michael Papadakis

Publikováno v: Circulation. 144

Introduction: Cascade family screening in inherited heart disease is often reserved for probands with a clinical diagnosis. This study assessed the yield of family screening in a national cardiac screening program, comparing a clinical and a clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31d017c44d8d4979a1d17b70e3ba71a1
https://doi.org/10.1161/circ.144.suppl_1.12832

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Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine

Publikováno v: Network and Systems Medicine
Network and Systems Medicine, 2020, 3 (1), pp.67-90. ⟨10.1089/nsm.2020.0004⟩
Network and systems medicine Online 3 (2020). doi:10.1089/nsm.2020.0004
info:cnr-pdr/source/autori:Blandine Comte 1, Jan Baumbach 2, Arriel Benis 3, José Basílio 4, Nata?a Debeljak 5, Åsmund Flobak 6 7, Christian Franken 8 9, Nissim Harel 3, Feng He 10 11, Martin Kuiper 12, Juan Albino Méndez Pérez 13, Estelle Pujos-Guillot 1, Tadeja Re?en 14, Damjana Rozman 14, Johannes A Schmid 4, Jeanesse Scerri 15, Paolo Tieri 16, Kristel Van Steen 17, Sona Vasudevan 18, Steven Watterson 19, Harald H H W Schmidt 20/titolo:Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine/doi:10.1089%2Fnsm.2020.0004/rivista:Network and systems medicine Online/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:3

Introduction: Network and systems medicine has rapidly evolved over the past decade, thanks to computational and integrative tools, which stem in part from systems biology. However, major challenges and hurdles are still present regarding validation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b09e5a4bbcb6a7fe330417bf4fcae0
https://hal.inrae.fr/hal-02957776/file/2020_Comte_Network_Syst_Med.pdf

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Bead-based RNA multiplex panels for biomarker detection in oncology samples

Autor: Christian Saliba, Godfrey Grech, Jeanesse Scerri, Shawn Baldacchino, Christian Scerri

Publikováno v: Methods. 158:86-91

Patient stratification, prognosis and disease monitoring are three important aspects of personalized cancer medicine. With traditional serum tumour protein biomarkers showing lack of specificity and sensitivity, and tumour heterogeneity affecting the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c97c2c952d3ba8a9b5681a96bd3d9b
https://doi.org/10.1016/j.ymeth.2018.10.008

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Abstract 1915: Intrinsic and acquired trastuzumab resistance pathways in breast cancer cell lines using DigiWest® phospho-protein profiling

Autor: Christian Scerri, Jeanesse Scerri, Godfrey Grech, Felix Ruoff, Markus F. Templin

Publikováno v: Cancer Research. 80:1915-1915

Introduction The widespread clinical use of monoclonal antibodies such as trastuzumab in personalized medicine, targeting upstream proteins such as receptors with cascading effects on downstream signaling, elicits the importance of studying the phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b4943d79e7613d19ce393da005dae26
https://doi.org/10.1158/1538-7445.am2020-1915

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Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Autor: Christian Scerri, Jeanesse Scerri, Christian Saliba, Shawn Baldacchino, Godfrey Grech

Publikováno v: Journal of visualized experiments : JoVE. (138)

Nucleic acid degradation in archival tissue, tumor heterogeneity, and a lack of fresh frozen tissue specimens can negatively impact cancer diagnostic services in pathology laboratories worldwide. Gene amplification and expression diagnostic testing u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7472ff781d9302666af1a5f67976799
https://pubmed.ncbi.nlm.nih.gov/30124640

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Prevalence

Autor: Jeanesse Scerri, Stefan Monecke, Michael A. Borg

Publikováno v: Journal of Epidemiology and Global Health, Vol 3, Iss 3, Pp 165-173 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::a1e58f4216f02ffb25a99477dc4f0051
http://www.sciencedirect.com/science/article/pii/S221060061300066X

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