Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jeanelle M. Martinez"'
Autor:
Jeanelle M. Martinez, Alison M. Pecquet, Melissa J. Vincent, Neeraja Erraguntla, Michael L. Dourson
Publikováno v:
Journal of Applied Toxicology
A no‐significant‐risk‐level of 20 mg day–1 was derived for tetrabromobisphenol A (TBBPA). Uterine tumors (adenomas, adenocarcinomas, and malignant mixed Müllerian) observed in female Wistar Han rats from a National Toxicology Program 2‐yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2428ddf79779fce3eb8bb95f758e1cd1
https://doi.org/10.1002/jat.3594
https://doi.org/10.1002/jat.3594
Autor:
Jeanelle M. Martinez, Thomas E. Eling
Publikováno v:
ALTEX.
Many volatile organic chemicals (VOCs) have not been tested for sensory pulmonary irritation. Development of in vitro non-animal sensory irritation assay suitable for large number of chemicals is needed to replace the mouse assay. An adverse outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54a1df77b7d6c74b2a130253be1f35a
https://doi.org/10.14573/altex.1811012
https://doi.org/10.14573/altex.1811012
Autor:
Stephen B. Reid, Jennifer A Finn, David L. MacIntosh, Michael L. Dourson, Kathleen Ward Brown, Lyle R. Chinkin, Jeanelle M. Martinez
Publikováno v:
Journal of the Air & Waste Management Association. 66:1061-1076
Petroleum coke or "petcoke" is a solid material created during petroleum refinement and is distributed via transfer facilities that may be located in densely populated areas. The health impacts from petcoke exposure to residents living in proximity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160776260a16df19282caaccdedec48a
https://doi.org/10.1080/10962247.2016.1180328
https://doi.org/10.1080/10962247.2016.1180328
Autor:
Colleen H. Anna, Curtis Hose, Thomas E. Eling, Nigel J. Walker, Anne Monks, Jeanelle M. Martinez, Ryuji Okazaki, Melinda G. Hollingshead, Tina Sali, Seung Joon Baek
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:899-906
A common in vitro response for many chemopreventive and antitumor agents, including some cyclooxygenase inhibitors, is the increased expression of nonsteroidal anti-inflammatory drug-activated gene (NAG)-1/macrophage inhibitory cytokine (MIC)-1/prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82abb32cb69f819e0d24aa1946d282d1
https://doi.org/10.1124/jpet.105.100081
https://doi.org/10.1124/jpet.105.100081
Publikováno v:
Environmental Health Perspectives
The neonatal mouse model has been a valuable tool in determining the long-term effects of early exposure to estrogenic agents in mammals. Using this model, we compared the effects of 2',4',6'-trichloro-4-biphenylol (OH-PCB-30) and 2',3',4',5'-tetrach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddce30fa34d57488449a524c1b34d372
http://europepmc.org/articles/PMC1280343
http://europepmc.org/articles/PMC1280343
Publikováno v:
Carcinogenesis. 25:349-357
Cox-1 and Cox-2 specific inhibitors exert chemo-preventative activity. However, the exact mechanisms for this activity remain unclear. Increasing evidence suggests that non-steroidal anti-inflammatory drugs regulate gene expression, which may be resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2de27188665bce10700da149eade80e
https://doi.org/10.1093/carcin/bgh016
https://doi.org/10.1093/carcin/bgh016
Autor:
Frank G. Bottone, Jeanelle M. Martinez, Thomas E. Eling, Jennifer B. Collins, Cynthia A. Afshari
Publikováno v:
Journal of Biological Chemistry. 278:25790-25801
The mechanisms underlying the anti-tumorigenic properties of cyclooxygenase inhibitors are not well understood. One novel hypothesis is alterations in gene expression. To test this hypothesis sulindac sulfide, which is used to treat familial adenomat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d161cf8469c285e227cab74225eb20a1
https://doi.org/10.1074/jbc.m301002200
https://doi.org/10.1074/jbc.m301002200
Autor:
Jeanelle M. Martinez, Takashi Takahashi, Akira Masuda, Nigel J. Walker, Pierre R. Bushel, Cynthia A. Afshari
Publikováno v:
Toxicological Sciences. 69:409-423
In humans, exposure to high levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with chronic obstructive pulmonary disease and lung cancer. While several studies have shown that the lung is a target organ for TCDD toxicity, little is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c986b629a11867191e6a3daab4886c3c
https://doi.org/10.1093/toxsci/69.2.409
https://doi.org/10.1093/toxsci/69.2.409
Autor:
Thomas E. Eling, Jong-Sik Kim, Ryuji Okazaki, Kiyoshi Yamaguchi, Jeanelle M. Martinez, Seong-Ho Lee, Yuji Mishina, Ahmed M. Shoieb, David Martin, Michael F. McEntee, Seung Joon Baek
Publikováno v:
Gastroenterology. 131(5)
Background & Aims: The nonsteroidal anti-inflammatory drug-activated gene (NAG-1) was identified as a proapoptotic, antitumorigenic protein in vitro, induced by many antitumorigenic and chemopreventive drugs including cyclooxygenase inhibitors. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165280251b35e8d6ca73e8b2e73b26dd
https://pubmed.ncbi.nlm.nih.gov/17383450
https://pubmed.ncbi.nlm.nih.gov/17383450
Autor:
Nigel J. Walker, Jeanelle M. Martinez
Publikováno v:
Toxicogenomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de8ef03bfa5a1d612898b23680c3440
https://doi.org/10.1002/0471669040.ch7
https://doi.org/10.1002/0471669040.ch7
