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pro vyhledávání: '"Jeana Yates"'
Publikováno v:
Endocrinology. 142:4994-5004
Inhibin is an important modulator of reproductive function at both the endocrine level, through its regulation of pituitary FSH biosynthesis, and at the paracrine and autocrine levels, as an intragonadal regulatory factor. To investigate the in vivo
Autor:
Dan Goldowitz, Stephanie Pretel, Yanxia Li, Warren A. Kibbe, Douglas J. Swanson, Carol J. Bult, Jay Snoddy, Jeana Yates, Wayne N. Frankel, Martha Holtz-Vitaterna, Joseph S. Takahashi
Publikováno v:
Brain research. Molecular brain research. 132(2)
N-ethyl-N-nitrosourea (ENU) mutagenesis is presented as a powerful approach to developing models for human disease. The efforts of three NIH Mutagenesis Centers established for the detection of neuroscience-related phenotypes are described. Each cent
Publikováno v:
Endocrinology. 142(11)
Inhibin and activin are structurally related dimeric peptide hormones and are members of the TGF-beta superfamily of proteins. In the accompanying paper, we describe transgenic mice that overexpress the inhibin alpha-subunit gene from a metallothione