Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jean-yves Gillon"'
Autor:
Vishal Goyal, Edrich Krantz, Francois Simon, Anouk Neven, Johanna Eriksson, Amaria Saayman, Nabila Ibnou Zekri Lassout, Mathieu Louis, Stephen Robinson, Abhijit Deshmukh, Amit Antarkar, Carol Ruffell, Sarika Victor, Marylore Chenel, Aljosa Celebic, Henri Caplain, Jean‐Yves Gillon, Isabela Ribeiro
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract The opportunistic fungal infection cryptococcal meningoencephalitis is a major cause of death among people living with HIV in sub‐Saharan Africa. We report pharmacokinetic (PK) and safety data from a randomized, four‐period crossover pha
Externí odkaz:
https://doaj.org/article/77be6bd1eca541ff837d7c0f07da6b62
Autor:
Alison Luckey, Emilie Alirol, Sophie Delhomme, John O'Donnell, Esther Bettiol, John Mueller, Seamus O'Brien, Jean‐Yves Gillon
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 5, Pp 770-780 (2023)
Abstract Gonorrhea is a sexually transmitted infection for which antibiotic treatment options have declined due to increasing antibiotic resistance. Zoliflodacin, an investigational oral spiropyrimidinetrione antibiotic with activity against Neisseri
Externí odkaz:
https://doaj.org/article/06e6f3f90fcb4202b94a93a19b09741c
Autor:
Alison Luckey, Emilie Alirol, Sophie Delhomme, John O'Donnell, Esther Bettiol, John Mueller, Seamus O'Brien, Jean‐Yves Gillon
Publikováno v:
Clinical and Translational Science. 16:770-780
Autor:
Sabine Specht, Natalie Strub-Wourgaft, Heino Stass, Belen Pedrique, Jeremy Dennison, Karen Dequatre-Cheeseman, Frans van den Berg, Sophie Delhomme, Frédéric Monnot, Claudia Peña-Rossi, Susanne Skrabs, Jean-Yves Gillon, Maria-Luisa Rodriguez
Aims: Emodepside is an anthelmintic, originally developed for veterinary use. We investigated the safety, pharmacokinetics, relative bioavailability and dose linearity of four oral formulations of emodepside in healthy male subjects. Methods: Three r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f70ac7813971a74eb5028e30b0fa036b
https://doi.org/10.22541/au.159863472.25422049
https://doi.org/10.22541/au.159863472.25422049
Autor:
Anthony Vocat, Jean-Yves Gillon, Stewart T. Cole, Andréanne Lupien, Caroline S. Foo, Vadim Makarov, Emilyne Blattes
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
The efficacy of the standardized four-drug regimen (comprising isoniazid, rifampin, pyrazinamide, and ethambutol) for the treatment of tuberculosis (TB) is menaced by the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) str
From Bench to Bedside: Development and Optimization of Clinical Therapies for Visceral Leishmaniasis
Publikováno v:
Drug Discovery for Leishmaniasis ISBN: 9781782628897
This chapter provides an overview of the different in vitro and in vivo strategies to progress a new compound for visceral leishmaniasis from early screening, through in vivo testing and potential translation, to clinical development, including the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a9c5eca9777c6f50d8ffe08742c96be
https://doi.org/10.1039/9781788010177-00037
https://doi.org/10.1039/9781788010177-00037