Zobrazeno 1 - 10
of 844
pro vyhledávání: '"Jean-Yves Scoazec"'
Autor:
Clémence Astier, Carine Ngo, Léo Colmet-Daage, Virginie Marty, Olivia Bawa, Claudio Nicotra, Maud Ngo-Camus, Antoine Italiano, Christophe Massard, Jean-Yves Scoazec, Cristina Smolenschi, Michel Ducreux, Antoine Hollebecque, Sophie Postel-Vinay
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-6 (2024)
Abstract Biliary tract cancers (BTCs) are heterogeneous malignancies with dismal prognosis due to tumor aggressiveness and poor response to limited current therapeutic options. Tumor exome profiling has allowed to successfully establish targeted ther
Externí odkaz:
https://doaj.org/article/0e99e403d1d04ae1bc389c998b7b3798
Autor:
Jean-Yves Scoazec, Francois-Xavier Danlos, Laurence Albiges, Bernard Escudier, Ronan Flippot, Lydie Cassard, Nathalie Chaput, Natacha Naoun, Marie Naigeon, Jean-Mehdi Jouniaux, Lisa Boselli, Lucia Carril-Ajuria, Marcus Teixeira, Macarena Rey-Cardenas, Larissa Rainho
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Immunotherapy profoundly changed the landscape of cancer therapy by providing long-lasting responses in subsets of patients and is now the standard of care in several solid tumor types. However, immunotherapy activity beyond conventional immune check
Externí odkaz:
https://doaj.org/article/4d45ec442ac34e56a8ca723b8b181cf8
Autor:
Delphine Bredel, Edi Tihic, Séverine Mouraud, François-Xavier Danlos, Sandrine Susini, Marine Aglave, Alexia Alfaro, Chifaou Mohamed-Djalim, Mathieu Rouanne, Héloise Halse, Amélie Bigorgne, Lambros Tselikas, Stéphane Dalle, Dana M. Hartl, Eric Baudin, Catherine Guettier, Eric Vibert, Olivier Rosmorduc, Caroline Robert, Sophie Ferlicot, Bastien Parier, Laurence Albiges, Vincent Thomas de Montpreville, Benjamin Besse, Olaf Mercier, Caroline Even, Ingrid Breuskin, Marion Classe, Camélia Radulescu, Thierry Lebret, Patricia Pautier, Sébastien Gouy, Jean-Yves Scoazec, Laurence Zitvogel, Aurélien Marabelle, Mélodie Bonvalet
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background In addition to anti-PD(L)1, anti-CTLA-4 and anti-LAG-3, novel immune checkpoint proteins (ICP)-targeted antibodies have recently failed to demonstrate significant efficacy in clinical trials. In these trials, patients were enrolle
Externí odkaz:
https://doaj.org/article/52536a48956445e0b8dee1144f166f82
Autor:
Wan Ching Lim, Maria Eugenia Marques Da Costa, Karine Godefroy, Eric Jacquet, Loren Gragert, Windy Rondof, Antonin Marchais, Naima Nhiri, Davide Dalfovo, Mathias Viard, Nizar Labaied, Asif M. Khan, Philippe Dessen, Alessandro Romanel, Claudia Pasqualini, Gudrun Schleiermacher, Mary Carrington, Laurence Zitvogel, Jean-Yves Scoazec, Birgit Geoerger, Jerome Salmon
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The human leukocyte antigen (HLA) system is a major factor controlling cancer immunosurveillance and response to immunotherapy, yet its status in pediatric cancers remains fragmentary. We determined high-confidence HLA genotypes in 576 children, adol
Externí odkaz:
https://doaj.org/article/b7bf7991e0734276842ecffd32168c0d
Autor:
Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J. Morscher, Anouchka Laurent, Sébastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaelle Pierron, Olivier Delattre, Gudrun Schleiermacher, Didier Surdez, Birgit Geoerger
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial (NCT02613962). To date, 1
Externí odkaz:
https://doaj.org/article/0bccef955fcd4460a5c66a0d211aaac0
Autor:
Maria Eugenia Marques da Costa, Robin Droit, Pierre Khneisser, Anne Gomez-Brouchet, Tiphaine Adam-de-Beaumais, Marie Nolla, Nicolas Signolles, Jacob Torrejon, Bérangère Lombard, Damarys Loew, Olivier Ayrault, Jean-Yves Scoazec, Birgit Geoerger, Gilles Vassal, Antonin Marchais, Nathalie Gaspar
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Osteosarcoma is a rare bone cancer in adolescents and young adults with a dismal prognosis because of metastatic disease and chemoresistance. Despite multiple clinical trials, no improvement in outcome has occurred in decades. There is an urgent need
Externí odkaz:
https://doaj.org/article/2a610dad48cc46c4805a492616f11430
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
According to the neuroendocrine tumour (NET) characteristics, 3 to 7 different treatment options are available, corresponding to 6 to 5,040 theoretical different sequences. Even though each patient is unique and despite a large heterogeneity in NET c
Externí odkaz:
https://doaj.org/article/fea303a8d3244ae2ab0a070b03e7a84d
Autor:
Voichita Suciu, Carolla El Chamieh, Ranya Soufan, Marie-Christine Mathieu, Corinne Balleyguier, Suzette Delaloge, Zsofia Balogh, Jean-Yves Scoazec, Sylvie Chevret, Philippe Vielh
Publikováno v:
Cancers, Vol 15, Iss 20, p 4967 (2023)
Fine-needle aspiration (FNA) cytology has been widely used for the diagnosis of breast cancer lesions with the objective of differentiating benign from malignant masses. However, the occurrence of unsatisfactory samples and false-negative rates remai
Externí odkaz:
https://doaj.org/article/d79e03b726ff4b4ab72ae4a49f8f1f3a
Autor:
Jérémy Guillot, Chloé Dominici, Adrien Lucchesi, Huyen Thi Trang Nguyen, Angélique Puget, Mélanie Hocine, Martha M. Rangel-Sosa, Milesa Simic, Jérémy Nigri, Fabienne Guillaumond, Martin Bigonnet, Nelson Dusetti, Jimmy Perrot, Jonathan Lopez, Anders Etzerodt, Toby Lawrence, Pierre Pudlo, Florence Hubert, Jean-Yves Scoazec, Serge A. van de Pavert, Richard Tomasini, Sophie Chauvet, Fanny Mann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The autonomic nervous systems densely innervate the pancreas, but its contribution to pancreatic ductal adenocarcinoma (PDAC) progression is not fully understood. Here, the authors characterize the pattern of sympathetic innervation by 3D imaging in
Externí odkaz:
https://doaj.org/article/f2a238503c59462b8745c93b2bc9627d
Autor:
Amélie Kasperek, Anthony Béguin, Olivia Bawa, Kévin De Azevedo, Bastien Job, Christophe Massard, Jean‐Yves Scoazec, Thierry Heidmann, Odile Heidmann
Publikováno v:
Molecular Oncology, Vol 16, Iss 7, Pp 1451-1473 (2022)
Human endogenous retroviruses represent approximately 8% of our genome. Most of these sequences are defective except for a few genes such as the ancestral retroviral HEMO envelope gene (Human Endogenous MER34 ORF), recently characterized by our group
Externí odkaz:
https://doaj.org/article/bbf96febdd1342ec8dc9c90731010fbc