Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jean-Sebastien Wattez"'
Publikováno v:
Developmental Dynamics
Background Numerous pathologies of pregnancy originate from placental dysfunction. It is essential to understand the functions of key genes in the placenta in order to discern the etiology of placental pathologies. A paucity of animal models that all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8c9187ad69246f803ecfe143f0fa11
http://europepmc.org/articles/PMC6488356
http://europepmc.org/articles/PMC6488356
Autor:
Lauren Lim, William W. Hay, Paul J. Rozance, Jianhua Shao, Liping Qiao, Jean-Sebastien Wattez
Publikováno v:
Diabetes
Diabetes, vol 68, iss 8
Diabetes, vol 68, iss 8
The main objective of this study was to investigate the effect of maternal obesity on offspring’s glucose metabolism during the perinatal period. Maternal obesity was established by feeding C57BL/6 mice with a high-fat (HF) diet before or during pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93294f797a324ab78d75ccf67ebb0737
https://doi.org/10.1530/ey.17.2.19
https://doi.org/10.1530/ey.17.2.19
Autor:
Shwetha K. Shetty, Liping Qiao, Kathryn M. Spitler, Jean-Sebastien Wattez, Brandon S.J. Davies, Jianhua Shao
Publikováno v:
Diabetes, vol 69, iss 6
Diabetes
Diabetes
To ensure fetal lipid supply, maternal blood triglyceride (TG) concentrations are robustly elevated during pregnancy. Interestingly, a lower increase in maternal blood TG concentrations has been observed in some obese mothers. We have shown that high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695d7c9495fc38ec51ac93d7a81c589f
https://escholarship.org/uc/item/5nc946v9
https://escholarship.org/uc/item/5nc946v9
Autor:
Liping Qiao, Jerome Schaack, Amanda Nguyen, William W. Hay, Jianhua Shao, Samuel Lee, Jean-Sebastien Wattez
Publikováno v:
Diabetes, vol 66, iss 5
Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq−/−) and wild-type (WT) mice were crossed to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bd113455bdce4e65e7dc33e9e20719
https://doi.org/10.2337/db16-1096
https://doi.org/10.2337/db16-1096
Autor:
Jianhua Shao, Hongfei Gao, William W. Hay, Liping Qiao, Jean-Sebastien Wattez, Kayee Chu, Gen-Sheng Feng, Samuel Lee
Publikováno v:
International journal of obesity (2005)
International journal of obesity (2005), vol 43, iss 9
International journal of obesity (2005), vol 43, iss 9
Background Excessive gestational weight gain (EGWG) closely associates with postpartum obesity. However, the causal role of EGWG in postpartum obesity has not been experimentally verified. The objective of this study was to determine whether and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909f46761aa0e46d3574e75e5a78355f
https://pubmed.ncbi.nlm.nih.gov/30622311
https://pubmed.ncbi.nlm.nih.gov/30622311
Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1
Autor:
Mana M. Parast, Jerome Schaack, Liping Qiao, Samuel Lee, Matteo Moretto Zita, William W. Hay, Jean-Sebastien Wattez, Zhuyu Guo, Jianhua Shao
Publikováno v:
Diabetologia, vol 59, iss 11
Aims/hypothesisThe main objective of this study was to investigate whether maternal adiponectin regulates fetal growth through the endocrine system in the fetal compartment.MethodsAdiponectin knockout (Adipoq (-/-) ) mice and in vivo adenovirus-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc9dd2c37caab8879ae3be5d2e41bcd
https://europepmc.org/articles/PMC5042853/
https://europepmc.org/articles/PMC5042853/
Autor:
Jean-Sébastien Wattez, Elodie Eury, Bethany C. Hazen, Alexa Wade, Sarah Chau, Shu-Ching Ou, Aaron P. Russell, Yoshitake Cho, Anastasia Kralli
Publikováno v:
Molecular Metabolism, Vol 68, Iss , Pp 101670- (2023)
Objective: Skeletal muscle oxidative capacity is central to physical activity, exercise capacity and whole-body metabolism. The three estrogen-related receptors (ERRs) are regulators of oxidative metabolism in many cell types, yet their roles in skel
Externí odkaz:
https://doaj.org/article/18008c4c47a1472590cc0304f9c81d5f
Autor:
Erin L. Brown, Bethany C. Hazen, Elodie Eury, Jean-Sébastien Wattez, Marin L. Gantner, Verena Albert, Sarah Chau, Manuel Sanchez-Alavez, Bruno Conti, Anastasia Kralli
Publikováno v:
iScience, Vol 2, Iss , Pp 221-237 (2018)
Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation. Long-term,
Externí odkaz:
https://doaj.org/article/24d87279e8a148f7a6c2a7388b0e7c79