Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jean-Sébastien Milanese"'
Autor:
Marie-Eve Lalonde, Marc Sasseville, Anne-Marie Gélinas, Jean-Sébastien Milanese, Kathie Béland, Simon Drouin, Elie Haddad, Richard Marcotte
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Acute lymphoblastic leukemia (ALL) is the most frequent cancer diagnosed in children. Despite the great progress achieved over the last 40 years, with cure rates now exceeding 85%, refractory or relapsed ALL still exhibit a dismal prognosis. This poo
Externí odkaz:
https://doaj.org/article/d57a115a81ba42dda8245482ff482329
Autor:
Jean-Sébastien Milanese, Edwin Wang
Publikováno v:
Systems Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb29d135fbf8beb7641f497ce9ddf554
https://doi.org/10.1016/b978-0-12-801238-3.11667-8
https://doi.org/10.1016/b978-0-12-801238-3.11667-8
Background: Immune evasion is a fundamental hallmark for cancer. At the early stages of tumor development, immune evasion strategies must be implemented by tumors to prevent attacks from the host immune systems. Blocking tumors’ immune evasion will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915a5657115c59e309611048a7e0ba4a
https://nrc-publications.canada.ca/eng/view/object/?id=cd23cdf0-19d4-4411-b976-125bc2d13447
https://nrc-publications.canada.ca/eng/view/object/?id=cd23cdf0-19d4-4411-b976-125bc2d13447
Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients
Autor:
Jean-Sébastien Milanese, Richard Marcotte, Zhigang Meng, Chabane Tibiche, Edwin Wang, Simon Drouin, Jinfeng Zou, André Nantel
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
Germline variants such as BRCA1/2 play an important role in tumorigenesis and clinical outcomes of cancer patients. However, only a small fraction (i.e., 5–10%) of inherited variants has been associated with clinical outcomes (e.g., BRCA1/2, APC, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab35c5fa4db5ebc9d830862d1ff38ce
https://doi.org/10.1038/s41698-019-0100-7
https://doi.org/10.1038/s41698-019-0100-7
Autor:
André Nantel, Pengyong Han, Edwin Wang, Jean-Sébastien Milanese, Chabane Tibiche, Jinfeng Zou, Naif Zaman, Arnaud Droit, Zhigang Meng
Germline genetic variants such as BRCA1/2 could play an important role in tumorigenesis and even clinical outcomes of cancer patients. These germline mutations have been used for genetic counselling and testing to establish as a standard-of-care proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56aa7dc7b8a84a2951607b7d32f51197
https://doi.org/10.1101/312355
https://doi.org/10.1101/312355
Autor:
Jean-Sébastien Milanese, Pengyong Han, Zhigang Meng, Jinfeng Zou, André Nantel, Edwin Wang, Chabane Tibiche, Naif Zaman, Arnaud Droit
Continual reduction in sequencing cost is expanding the accessibility of genome sequencing data for routine clinical applications. However, the lack of methods to construct machine learning-based predictive models using these datasets has become a cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584f567f1e4ee76c5c1e89277072ba11
Autor:
Jean-Sébastien Milanese, Edwin Wang
Publikováno v:
Breast Cancer Management. 8:BMT23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8d5c0497471a0ab525802f0700ddbf
https://doi.org/10.2217/bmt-2019-0005
https://doi.org/10.2217/bmt-2019-0005
Autor:
Naif Zaman, Ali Masoudi-Nejad, Jean-Sébastien Milanese, Edwin Wang, Shauna Mcgee, Maureen D. O'Connor-McCourt
We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an attempt to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c6dcc1d16c789db81d04c13a893dd7
https://doi.org/10.1016/j.semcancer.2014.04.002
https://doi.org/10.1016/j.semcancer.2014.04.002