Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jean-Roger Claude"'
Autor:
Jean-Roger Claude, Stephane De Jouffrey, François Dargent, Cecile Fisch, Mahmoud Attia, Isabelle Dupin-Roger
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 98:442-446
This study was aimed at evaluating the digestive tolerance of the new antiosteoporotic drug, strontium ranelate, and to compare it to that of another strontium salt, strontium chloride (SrCl2). Strontium ranelate, SrCl2, or placebo were administered
Autor:
M. Thevenin, Géraldine Villain-Pautet, He Hua, Chuong Pham-Huy, Hervé Galons, Jean-Michel Warnet, Jean-Roger Claude, Nassima Chikhi-Chorfi
Publikováno v:
Journal of Biochemical and Biophysical Methods. 54:287-299
The enantioselective high-performance liquid chromatography (HPLC) of three racemic 3-hydroxybenzodiazepines, oxazepam (Oxa), lorazepam (Lor), and temazepam (Tem), is a difficult operation because of the spontaneous chiral inversion in polar solvent.
Autor:
Jean-Roger Claude
Publikováno v:
Fundamental and Clinical Pharmacology. 16:75-78
Until the year 2000 there was no internationally-accepted definition for the terms used in nonclinical pharmacology (primary, secondary pharmacodynamics, discovery, safety pharmacology, etc). Now, after ICH5 (San Diego, November 2000), a harmonisatio
Autor:
Jean-Roger Claude, Jean-Michel Warnet, G. E. Rosselin, Pierre Ducimetière, Eveline Eschwège, N Thibult, Annick Fontbonne, Marie-Aline Charles
Publikováno v:
American Journal of Epidemiology. 153:292-298
To assess the association of fasting plasma nonesterified fatty acid (NEFA) concentration with the risk of death from coronary heart disease and cancer, the authors computed 15-year mortality rates for the 4,589 working men aged 43-53 years who were
Autor:
Hervé Galons, Jean-Roger Claude, Nassima Chikhi-Chorfi, Jean-Michel Warnet, M. Thevenin, Chuong Pham-Huy
Publikováno v:
Chirality. 13:187-192
Selective antibodies to (R)-methadone (Mtd) and to its racemate were produced in rabbits by immunization with conjugates of (R)- or (R,S)-hemisuccinyl-methadol-bovine serum albumin, respectively. A hapten was first prepared by reduction of (R)- or (R
Autor:
Alain Sarasin, Gilberto Antonio De Oliveira, Sophie Ellouk-Achard, Huynh Thien Duc, Sepideh Djenabi, Geneviève Desauty, Jean Roger Claude, Mishal Zohair, C. Lafarge-Frayssinet, Jerzy Trojan
Publikováno v:
Journal of Hepatology. 29:807-818
Background/Aims: We have developed a gene therapy strategy based on the observation that insulin-like growth factor I (IGF-I) is necessary for the acquisition and maintenance of the transformed phenotype in hepatocarcinoma. This strategy consists in
Autor:
G. E. Rosselin, Marie-Aline Charles, Jean-Michel Warnet, Jean-Roger Claude, B. Balkau, Jean-Philippe Girard, N Thibult, Eveline Eschwège
Publikováno v:
Diabetologia. 40:1101-1106
Although an increased plasma non-esterified fatty acid (NEFA) concentration has been shown to increase insulin resistance (Randle cycle), decrease insulin secretion and increase hepatic gluconeogenesis, the effect of NEFA on the deterioration of gluc
Autor:
Jeanine Voisin, Jean-Michel Warnet, Hervé Galons, Simone Righenzi, H.T. Duc, Jean-Roger Claude, Jiarong Zhu, Chuong Pham-Huy
Publikováno v:
International Journal of Immunopharmacology. 19:289-296
Thalidomide (Thd) has been shown to have interesting immunosuppressive properties and strong action against TNF-α. It is used for treating a variety of immune-mediated pathology and inflammatory diseases. The purpose of this work was to evaluate the
Autor:
Sylvie Robin, Pham-Huy Chuong, Hervé Galons, Bernard Viossat, Jiarong Zhu, Jean Roger Claude, Alain Tomas
Publikováno v:
Tetrahedron: Asymmetry. 6:1249-1252
Benzyloxyamine reacted with BOC-glutamic-α-phenyl ester in the presence of carbodiimide to give BOC-amino-N-benzyloxypiperidinedione. Deprotection of the amino group followed by phthaloylation led to N-benzyloxythalidomide which was then converted i
Autor:
Cecile, Fisch, Mahmoud, Attia, François, Dargent, Stéphane, de Jouffrey, Isabelle, Dupin-Roger, Jean-Roger, Claude
Publikováno v:
Basicclinical pharmacologytoxicology. 98(5)
This study was aimed at evaluating the digestive tolerance of the new antiosteoporotic drug, strontium ranelate, and to compare it to that of another strontium salt, strontium chloride (SrCl2). Strontium ranelate, SrCl2, or placebo were administered