Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jean-Pierre Samama"'
Autor:
Nada Lallous, Pierre Legrand, Alastair G McEwen, Santiago Ramón-Maiques, Jean-Pierre Samama, Catherine Birck
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27599 (2011)
The human UHRF1 protein (ubiquitin-like containing PHD and RING finger domains 1) has emerged as a potential cancer target due to its implication in cell cycle regulation, maintenance of DNA methylation after replication and heterochromatin formation
Externí odkaz:
https://doaj.org/article/7735bc4d7b0448b0b79ac24617ac673a
Autor:
François Polack, Vincent Le Roux, Pascal Philippot, Marc Ribbens, Andrea Somogyi, Kadda Medjoubi, Jean Pierre Samama, G. Baranton
Publikováno v:
Journal of Synchrotron Radiation. 22:1118-1129
The Nanoscopium 155 m-long beamline of Synchrotron Soleil is dedicated to scanning hard X-ray nanoprobe techniques. Nanoscopium aims to reach ≤100 nm resolution in the 5–20 keV energy range for routine user experiments. The beamline design tackle
Publikováno v:
Synchrotron Radiation News. 21:6-9
January 2008 was the time of the official opening of SOLEIL's beamlines and guest house. This transition from construction to operational phase was made possible after commissioning of the 17°C water circuits of the beamlines. Users have access to e
Publikováno v:
Journal of Biological Chemistry. 277:42003-42010
DivK is an essential response regulator in the Gram-negative bacterium Caulobacter crescentus and functions in a complex phosphorelay system that precisely controls the sequence of developmental events during the cell division cycle. Structure determ
Publikováno v:
Journal of Molecular Biology. 321:447-457
Two-component regulatory systems mediate most of the bacterial cells responses to a variety of signals. In Sinorhizobium meliloti, the FixL-FixJ couple controls the expression of the nitrogen fixation genes through the binding of the two-domains resp
Autor:
Yun Zhang, Sergei B. Vakulenko, Samy O. Meroueh, Dasantila Golemi, Shahriar Mobashery, Pierre Roblin, Jean-Pierre Samama, Laurent Maveyraud
Publikováno v:
Journal of the American Chemical Society. 124:9422-9430
Clavulanate, an inhibitor for beta-lactamases, was the very first inhibitor for an antibiotic resistance enzyme that found clinical utility in 1985. The clinical use of clavulanate and that of sulbactam and tazobactam, which were introduced to the cl
Autor:
Sergei B. Vakulenko, Jean-Pierre Samama, Laurent Maveyraud, Dasantila Golemi, Shahriar Mobashery
Publikováno v:
Proceedings of the National Academy of Sciences. 98:14280-14285
β-Lactamases are the resistance enzymes for β-lactam antibiotics, of which four classes are known. β-lactamases hydrolyze the β-lactam moieties of these antibiotics, rendering them inactive. It is shown herein that the class D OXA-10 β-lactamase
Autor:
Valérie Guillet, Jean-Pierre Samama, Samuel Tranier, Laurent Maveyraud, Wladimir Sougakoff, Anne-Typhaine Bouthors
Publikováno v:
Europe PubMed Central
The treatment of infectious diseases by beta-lactam antibiotics is continuously challenged by the emergence and dissemination of new beta-lactamases. In most cases, the cephalosporinase activity of class A enzymes results from a few mutations in the
Autor:
Henri Monteil, Gilles Prévost, L. Baba Moussa, Jean-Denis Pedelacq, Ambaliou Sanni, Jean-Pierre Samama, Didier A. Colin, Sandra Werner, Lionel Mourey
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 1999, 461 (3), pp.280-286. ⟨10.1016/s0014-5793(99)01453-2⟩
FEBS Letters, Wiley, 1999, 461 (3), pp.280-286. ⟨10.1016/s0014-5793(99)01453-2⟩
International audience; The consecutive cell activation, including Ca 2+-channel opening, and pore formation leading to human neutrophil lysis were the two functions of the staphylococcal Panton-Valentine leucocidin attempted to be discoupled by site
Autor:
Peter Swarén, Shahriar Mobashery, Stéphanie Cabantous, Jean-Pierre Samama, Alexey Bulychev, Laurent Maveyraud, Dasantila Golemi
Publikováno v:
Biochemistry. 38:9570-9576
The clinical use of beta-lactam antibiotics combined with beta-lactamase inactivators, such as clavulanate, has resulted in selection of beta-lactamases that are insensitive to inactivation by these molecules. Therefore, therapeutic combinations of a