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Autor:
Fabienne Malagnac, Céline Fabret, Magali Prigent, Jean-Pierre Rousset, Olivier Namy, Philippe Silar
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73772 (2013)
In the model fungus Podospora anserina, the PaYIP3 gene encoding the orthologue of the Saccharomyces cerevisiae YIP3 Rab-GDI complex dissociation factor expresses two polypeptides, one of which, the long form, is produced through a programmed transla
Externí odkaz:
https://doaj.org/article/4af63b8fd12b494fa9a2b9f372385b68
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002608 (2012)
The efficiency of translation termination depends on the nature of the stop codon and the surrounding nucleotides. Some molecules, such as aminoglycoside antibiotics (gentamicin), decrease termination efficiency and are currently being evaluated for
Externí odkaz:
https://doaj.org/article/3ba02b3d5d0149ea900e25bb7748d488
Autor:
Bruno Cosnier, Marta Kwapisz, Isabelle Hatin, Olivier Namy, Sylvie Hermann-Le Denmat, Antonin Morillon, Jean-Pierre Rousset, Céline Fabret
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19500 (2011)
In Saccharomyces cerevisiae, the essential IMP3 gene encodes a component of the SSU processome, a large ribonucleoprotein complex required for processing of small ribosomal subunit RNA precursors. Mutation of the IMP3 termination codon to a sense cod
Externí odkaz:
https://doaj.org/article/327deda465694070a02ce828946d1670
Autor:
Bruno Cosnier, Marta Kwapisz, Isabelle Hatin, Olivier Namy, Sylvie Hermann-Le Denmat, Antonin Morillon, Jean-Pierre Rousset, Céline Fabret
Publikováno v:
PLoS ONE, Vol 6, Iss 5 (2011)
Externí odkaz:
https://doaj.org/article/73c8e097db4b46f9bef8ede9b3f6b385
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24125 (2011)
The APC tumor suppressor gene is frequently mutated in human colorectal cancer, with nonsense mutations accounting for 30% of all mutations in this gene. Reintroduction of the WT APC gene into cancer cells generally reduces tumorigenicity or induces
Externí odkaz:
https://doaj.org/article/aa6a0886d17d434bbe18a601b8e9c916
Autor:
Christopher Deutsch, Basma El Yacoubi, Isabelle Hatin, Valérie de Crécy-Lagard, Jean-Pierre Rousset, Alexey G. Murzin, Dirk Iwata-Reuyl, Tamer Kahveci
Publikováno v:
The EMBO Journal. 30:882-893
The YgjD/Kae1 family (COG0533) has been on the top-10 list of universally conserved proteins of unknown function for over 5 years. It has been linked to DNA maintenance in bacteria and mitochondria and transcription regulation and telomere homeostasi
Publikováno v:
FEMS Yeast Research. 10:1070-1082
Errors occur randomly and at low frequency during the translation of mRNA. However, such errors may also be programmed by the sequence and structure of the mRNA. These programmed events are called ‘recoding’ and are found mostly in viruses, in wh
Autor:
Victor L. Thijssen, Mireille Viguier, Jerome Collignon, Ralph Jacob, Tien Dang, Jean Pierre Rousset, Johannes Ludger, Delphine Delacour, Hakon Leffler, Gabriel A. Rabinovich
Publikováno v:
Glycobiology, 28(6), 348-348. Oxford University Press
Collignon, J, Dang, T, Delacour, D, Jacob, R, Leffler, H, Ludger, J, Rabinovich, G A, Rousset, J P, Thijssen, V L & Viguier, M 2018, ' A tribute to Francoise Poirier (1954-2018) ', Glycobiology, vol. 28, no. 6, pp. 348-348 . https://doi.org/10.1093/glycob/cwy036
Collignon, J, Dang, T, Delacour, D, Jacob, R, Leffler, H, Ludger, J, Rabinovich, G A, Rousset, J P, Thijssen, V L & Viguier, M 2018, ' A tribute to Francoise Poirier (1954-2018) ', Glycobiology, vol. 28, no. 6, pp. 348-348 . https://doi.org/10.1093/glycob/cwy036
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2009, 37 (6), pp.1789-98. ⟨10.1093/nar/gkp012⟩
Nucleic Acids Research, Oxford University Press, 2009, 37 (6), pp.1789-98. ⟨10.1093/nar/gkp012⟩
International audience; Translation termination in eukaryotes is completed by two interacting factors eRF1 and eRF3. In Saccharomyces cerevisiae, these proteins are encoded by the genes SUP45 and SUP35, respectively. The eRF1 protein interacts direct