Major molecular response achievement in CML Patients can be predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS ratio at an earlier time point of follow-up than currently recommended.

Autor: Sarah Huet, Pascale Cony-Makhoul, Maël Heiblig, Isabelle Tigaud, Sophie Gazzo, Amine Belhabri, Denis Souche, Mauricette Michallet, Jean-Pierre Magaud, Sandrine Hayette, Franck Nicolini

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e106250 (2014)

Recent studies demonstrate that early molecular response to tyrosine-kinase inhibitors is strongly predictive of outcome in chronic myeloid leukemia patients and that early response landmarks may identify patients at higher risk for transformation wh

Externí odkaz: https://doaj.org/article/498ed52ee0b7482794675902f313cfd5

Exome sequencing identifies recurrent BCOR alterations and the absence of KLF2 , TNFAIP3 and MYD88 mutations in splenic diffuse red pulp small B-cell lymphoma

Autor: Françoise Berger, Pierre Sujobert, Sarah Huet, Kaddour Chabane, Gilles Salles, David Salgado, Sandrine Hayette, Pascale Felman, Aurélie Verney, Laurent Genestier, Evelyne Callet-Bauchu, Jean-Pierre Desvignes, Jean-Pierre Magaud, Lucile Baseggio, Alexandra Traverse-Glehen, Laurent Jallades, Christophe Béroud, Nicolas Lévy

Publikováno v: Haematologica. 102:1758-1766

Splenic diffuse red pulp lymphoma is an indolent small B-cell lymphoma recognized as a provisional entity in the World Health Organization 2008 classification. Its precise relationship to other related splenic B-cell lymphomas with frequent leukemic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08ed558022565b974f5282ce9510cd20
https://doi.org/10.3324/haematol.2016.160192

Toll-like receptor expression and function differ between splenic marginal zone B cell lymphoma and splenic diffuse red pulp B cell lymphoma

Autor: Aurélie Verney, Laurent Jallades, Evelyne Callet-Bauchu, Laurent Genestier, Gilles Salles, Alexandra Traverse-Glehen, Jean-Pierre Magaud, Lucile Baseggio

Publikováno v: Oncotarget
Oncotarget, 2018, 9 (34), pp.23589-23598. ⟨10.18632/oncotarget.25283⟩
Oncotarget, Impact journals, 2018, 9 (34), pp.23589-23598. ⟨10.18632/oncotarget.25283⟩

International audience; In splenic marginal zone lymphoma (SMZL), specific and functional Toll-like Receptor (TLR) patterns have been recently described, suggesting their involvement in tumoral proliferation. Splenic diffuse red pulp lymphoma with vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49848d7cf1439f7f3a0ca7b8fb45430
https://hal.science/hal-01859559

Absence of driver mutations in persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes

Autor: Alexandra Traverse-Glehen, Jean-Pierre Magaud, Lucile Baseggio, Sarah Huet, Christine Bole-Feysot, Evelyne Callet-Bauchu, Jean-Christophe Lega, Pierre Sujobert, Gilles Salles, Pascale Felman, Bruno Tesson, Laurent Jallades, Béatrice Grange

Publikováno v: Blood. 130(10)

To the editor: Most hematologic malignancies are preceded by a premalignant condition. In myeloid neoplasms, genetically defined premalignant conditions such as clonal hematopoiesis of indeterminate potential[1][1] reflect the clonal dominance of hem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8342cd08a500c9978bdd2b63c6c818c
https://pubmed.ncbi.nlm.nih.gov/28679739

New Quantitative Method to Identify NPM1 Mutations in Acute Myeloid Leukaemia

Autor: Franck E. Nicolini, Sandrine Hayette, Jean-Pierre Magaud, Mauricette Michallet, Sarah Huet, Kaddour Chabane, Carole Charlot, Laurent Jallades

Publikováno v: Leukemia Research and Treatment

Somatic mutations in the NPM1 gene, which encodes for nucleophosmin, have been reported to be the most frequent genetic abnormalities found in acute myeloid leukaemia (AML). Their identification and quantification remain crucial for the patients’ r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10edac12eeac11cc6aa7919e05047a50
https://doi.org/10.1155/2013/756703