Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jean-Pierre Issa"'
Autor:
Jianfeng Xu, Jiejun Shi, Xiaodong Cui, Ya Cui, Jingyi Jessica Li, Ajay Goel, Xi Chen, Jean-Pierre Issa, Jianzhong Su, Wei Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Here, the authors introduce Cell Heterogeneity–Adjusted cLonal Methylation (CHALM) as a methylation quantification method that considers the heterogeneity of sequenced bulk cells. They apply CHALM to methylation datasets to detect differentially me
Externí odkaz:
https://doaj.org/article/b40f1c110ebc470486f84acea582f1c8
Autor:
Shan He, Yongnian Liu, Lijun Meng, Hongxing Sun, Ying Wang, Yun Ji, Janaki Purushe, Pan Chen, Changhong Li, Jozef Madzo, Jean-Pierre Issa, Jonathan Soboloff, Ran Reshef, Bethany Moore, Luca Gattinoni, Yi Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
During an immune response naive CD8+ T cells can differentiate into either effector or memory T cells. Here the authors show that Akt-mediated phosphorylation of the epigenetic regulator Ezh2 is critical for the generation of an anti-tumor CD8 T cell
Externí odkaz:
https://doaj.org/article/865ed17d49994e7abe49c981111342a5
Autor:
Tadeusz Majewski, Hui Yao, Jolanta Bondaruk, Woonbok Chung, Sangkyou Lee, June Goo Lee, Shizhen Zhang, David Cogdell, Guoliang Yang, Woonyoung Choi, Colin Dinney, H. Barton Grossman, Christopher Logothetis, Steven E. Scherer, Charles C. Guo, Li Zhang, Peng Wei, John N. Weinstein, Jean-Pierre Issa, Keith Baggerly, David J. McConkey, Bogdan Czerniak
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2241-2256.e4 (2019)
Summary: We used whole-organ mapping to study the locoregional molecular changes in a human bladder containing multifocal cancer. Widespread DNA methylation changes were identified in the entire mucosa, representing the initial field effect. The fiel
Externí odkaz:
https://doaj.org/article/203291d70e8e4971a986b615aa97b626
Autor:
Pierre Saintigny, Li Mao, Scott M. Lippman, Jean-Pierre Issa, Jeffrey N. Myers, J. Jack Lee, Adel K. El-Naggar, Waun K. Hong, You H. Fan, Edward S. Kim, Li Zhang, Lei Feng, Wenhua Lang, Jing Wang, Mitchell J. Frederick, William N. William, Steven H. Lin, Jaroslav Jelinek, Vassiliki A. Papadimitrakopoulou, Curtis R. Pickering, Jean-Philippe Foy
DNA promoter methylation of tumor suppressor genes and global DNA hypomethylation are common features of head and neck cancers. Our goal was to identify early DNA methylation changes in oral premalignant lesions (OPL) that may serve as predictive mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7129b6dc728d1379703dd57ccf22fa
https://doi.org/10.1158/1940-6207.c.6544334.v1
https://doi.org/10.1158/1940-6207.c.6544334.v1
Autor:
Pierre Saintigny, Li Mao, Scott M. Lippman, Jean-Pierre Issa, Jeffrey N. Myers, J. Jack Lee, Adel K. El-Naggar, Waun K. Hong, You H. Fan, Edward S. Kim, Li Zhang, Lei Feng, Wenhua Lang, Jing Wang, Mitchell J. Frederick, William N. William, Steven H. Lin, Jaroslav Jelinek, Vassiliki A. Papadimitrakopoulou, Curtis R. Pickering, Jean-Philippe Foy
Supplementary Figure 1: Flow-chart describing the selection of 86 candidate genes. Supplementary Figure 2: Promoter methylation of 62/86 candidate genes in head and neck cancer, normal mucosa and blood. Supplementary Figure 3: Promoter methylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ccf8e8048dba0dcbc215515a168af8
https://doi.org/10.1158/1940-6207.22524611.v1
https://doi.org/10.1158/1940-6207.22524611.v1
Autor:
Pierre Saintigny, Li Mao, Scott M. Lippman, Jean-Pierre Issa, Jeffrey N. Myers, J. Jack Lee, Adel K. El-Naggar, Waun K. Hong, You H. Fan, Edward S. Kim, Li Zhang, Lei Feng, Wenhua Lang, Jing Wang, Mitchell J. Frederick, William N. William, Steven H. Lin, Jaroslav Jelinek, Vassiliki A. Papadimitrakopoulou, Curtis R. Pickering, Jean-Philippe Foy
Supplementary Table 1: Description of the studies used for the in silico validation of the candidate genes in terms of number of samples analyzed, platform used and number of overlapping genes between our candidate gene list and the genes analyzed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddf7503cc1828160ff2ce3afb97a1c5
https://doi.org/10.1158/1940-6207.22524608
https://doi.org/10.1158/1940-6207.22524608
Autor:
Luigi Ricciardiello, C. Richard Boland, Jean-Pierre Issa, Robert M. Genta, Antonio Gasbarrini, Susanne W. Carmack, Paola Vitaglione, Giulia Graziani, Marco Romano, Vincenzo Fogliano, Melissa Garcia, Shinji Maegawa, Michael Selgrad, Yahya Daoud, Giulia Piazzi, Lucia Fini
Supplementary Materials from Chemoprevention of Intestinal Polyps in ApcMin/+ Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d373efe9115370ed5a96935a4e7999
https://doi.org/10.1158/1940-6207.22524042.v1
https://doi.org/10.1158/1940-6207.22524042.v1
Autor:
Kirsten Grønbaek, Imran Siddiqi, Stephen B. Baylin, Peter Jones, Jean-Pierre Issa, Sine Reker Hadrup, Benjamin A. Youngblood, Galen Hostetter, Ryan Burgos, Kristin Horwood, Brett T. Brinker, Jack Cowland, Staffan Holmberg-Thyden, Ashkan Emadi, Hyo Sik Jang, Denice Tsao-Wei, Jakob Werner Hansen, Patricia Kropf, Vu H. Duong, Sunil Kumar Saini, Andreas Due Ørskov, Maria R. Baer, Casey L. O'Connell
A. Gating strategy applied for flow cytometry analysis of NK cell panel. Phenotype of NK cell (CD56dim CD16+ ) activation was quantified using expression of cell surface markers CD69, CD107a, CD45RA, and CD45RO based on the indicated gates. B. NK cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b765c5b3b50376109072d9c6bb4e80
https://doi.org/10.1158/1078-0432.22489686.v1
https://doi.org/10.1158/1078-0432.22489686.v1
Autor:
Kirsten Grønbaek, Imran Siddiqi, Stephen B. Baylin, Peter Jones, Jean-Pierre Issa, Sine Reker Hadrup, Benjamin A. Youngblood, Galen Hostetter, Ryan Burgos, Kristin Horwood, Brett T. Brinker, Jack Cowland, Staffan Holmberg-Thyden, Ashkan Emadi, Hyo Sik Jang, Denice Tsao-Wei, Jakob Werner Hansen, Patricia Kropf, Vu H. Duong, Sunil Kumar Saini, Andreas Due Ørskov, Maria R. Baer, Casey L. O'Connell
Specific genes sequenced in bone marrow mononuclear cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba01aa6609992cc932f7ea2364bda388
https://doi.org/10.1158/1078-0432.22489680.v1
https://doi.org/10.1158/1078-0432.22489680.v1
Autor:
Kirsten Grønbaek, Imran Siddiqi, Stephen B. Baylin, Peter Jones, Jean-Pierre Issa, Sine Reker Hadrup, Benjamin A. Youngblood, Galen Hostetter, Ryan Burgos, Kristin Horwood, Brett T. Brinker, Jack Cowland, Staffan Holmberg-Thyden, Ashkan Emadi, Hyo Sik Jang, Denice Tsao-Wei, Jakob Werner Hansen, Patricia Kropf, Vu H. Duong, Sunil Kumar Saini, Andreas Due Ørskov, Maria R. Baer, Casey L. O'Connell
Isolation and DNA extraction of bone marrow cell populations; Targeted DNA sequencing; Peripheral blood mononuclear cell (PBMC) staining and flow cytometry analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbe44b362dc75acc4821bf32f83712e
https://doi.org/10.1158/1078-0432.22489683
https://doi.org/10.1158/1078-0432.22489683