Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jean-Pierre Gagner"'
Autor:
Amber A. Guth, Jean Pierre Gagner, Deborah Axelrod, Bradley E. Aouizerat, Mei R. Fu, Jeanna M. Qiu, Gary Yu, David Zagzag, Yvette P. Conley
Publikováno v:
Current breast cancer reports
Purpose of the Study More than 50% of breast cancer survivors without a diagnosis of lymphedema suffer daily from numerous and co-occurring lymphedema symptoms. This study aimed to identify lymphedema symptom patterns and the association of such patt
Autor:
Xin Cui, Renee-Tyler Tan Morales, Weiyi Qian, Haoyu Wang, Jean-Pierre Gagner, Igor Dolgalev, Dimitris Placantonakis, David Zagzag, Luisa Cimmino, Matija Snuderl, Raymond H.W. Lam, Weiqiang Chen
Publikováno v:
Biomaterials. 287:121667
Autor:
Kasthuri Kannan, Jean-Pierre Gagner, Elad Mashiach, Adriana Heguy, Matija Snuderl, David Zagzag, Matthias A. Karajannis
Publikováno v:
Neuro Oncol
BACKGROUND While most hemangioblastomas (~70%) are sporadic and occur predominantly in the cerebellum, they may present as well as familial form associated with von Hippel-Lindau (VHL) syndrome, an autosomal dominant disorder caused by germline mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad606035c86a24c73ca6425e5911af9
https://europepmc.org/articles/PMC6847755/
https://europepmc.org/articles/PMC6847755/
Autor:
Matija Snuderl, Shruti Nayak, Mirna Lechpammer, Jean-Pierre Gagner, Varshini Vasudevaraja, Beatrix Ueberheide, David Zagzag, Scott Kamen, Ramona Bledea, Jonathan Serrano
BACKGROUND: Tumor heterogeneity presents a major challenge to cancer diagnosis and treatment. In addition to interpatient tumor variability, intratumoral heterogeneity characterized by distinct molecular and phenotypic profiles is increasingly recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51fcbc20cd6c1caa273f45af2ed7e5f
https://europepmc.org/articles/PMC6216566/
https://europepmc.org/articles/PMC6216566/
Autor:
Evgeny Nudler, Jean-Pierre Gagner, Taryn Morningstar, Mirna Lechpammer, David Zagzag, Ralph Green, Zachary Rabow, Kiarash Shahlaie, Fady Girgis
Isocitrate dehydrogenase (IDH) mutation have been reported to impose in gliomas a shortage of NADPH required to maintain a redox state and may rely on cysteine (Cys) availability for biosynthesis of glutathione (GSH) to ensure antioxidant levels. Cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f7a13a480b68a76da2e2de51f97c0c
https://europepmc.org/articles/PMC6217022/
https://europepmc.org/articles/PMC6217022/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1741
To simulate and study the hypoxic microenvironment associated with intracerebral glioma in vivo, simple and reproducible methods are described and discussed for inducing hypoxia or chemical pseudohypoxia in glioma cell cultures and assessing their ef
Autor:
Jean-Pierre Gagner, David Zagzag
Publikováno v:
Methods in Molecular Biology ISBN: 9781493976584
Among various methods now available to isolate distinct cell populations or even single cells for DNA/RNA and proteomic analysis, laser capture microdissection (LCM) offers a unique opportunity to study cells in their topological contexts. This chapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::821f4d4e166d4d2612df3101b3762115
https://doi.org/10.1007/978-1-4939-7659-1_17
https://doi.org/10.1007/978-1-4939-7659-1_17
Publikováno v:
Methods in Molecular Biology ISBN: 9781493976584
To simulate and study the hypoxic microenvironment associated with intracerebral glioma in vivo, simple and reproducible methods are described and discussed for inducing hypoxia or chemical pseudohypoxia in glioma cell cultures and assessing their ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0efd2697f1c020278924cdc4430b7361
https://doi.org/10.1007/978-1-4939-7659-1_9
https://doi.org/10.1007/978-1-4939-7659-1_9
Autor:
Matija Snuderl, Raymond W. Lam, Xin Cui, Weiyi Qian, Jean Pierre Gagner, Haoyu Wang, Renee Tyler Tan Morales, Luisa Cimmino, Igor Dolgalev, David Zagzag, Weiqiang Chen, Dimitris G. Placantonakis
Publikováno v:
Biomaterials
Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is hallmarked by distorted neovascularization, diffuse tumor-associated macrophage infiltration, and potent immunosuppression. Reconstituting organotypic tumor angiogen
Autor:
Valerio Ortenzi, Garry Douglas, Barbara Romagnoli, Yasmeen Sarfraz, Fawaz M. Alotaibi, Awab T. Tayyib, Luis Chiriboga, David Zagzag, Jean-Pierre Gagner, Guillaume Lemercier, Eric Chevalier, Klaus Dembowsky, Michel Schmitt, Gerald Tuffin
Resistance to antiangiogenic therapy in glioblastoma (GBM) patients may involve hypoxia-induced expression of C-X-C motif chemokine receptor 4 (CXCR4) on invading tumor cells, macrophage/microglial cells (MGCs), and glioma stem cells (GSCs). We deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427df2b12f9e81f1788e20147d820c2a
https://europepmc.org/articles/PMC5809520/
https://europepmc.org/articles/PMC5809520/