Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Jean-Pierre Finet"'
Autor:
Alexey Yu. Fedorov, Véronique Bourgarel-Rey, Jean Boutonnat, Vincent Peyrot, Soazig Douillard, Pascale Barbier, Jean-Pierre Finet, Anne McLeer-Florin, Sebastien Combes, Jean-Thomas Pierson
Publikováno v:
Journal of Medicinal Chemistry. 54:3153-3162
A series of A-ring variously methoxylated 4-(3-hydroxy-4-methoxyphenyl)coumarins related to combretastatin A-4 was prepared by cross-coupling reactions. Cytotoxicity studies indicated a potent activity against HBL100 cell line. Substitution patterns
Autor:
Sébastien Combes, Aurélien Dumètre, Jean-Pierre Finet, Jean-Thomas Pierson, Nadine Azas, F. Delmas, Michèle Laget, Sébastien Hutter
Publikováno v:
European Journal of Medicinal Chemistry. 45:864-869
A large series of 4-arylcoumarins was synthesized by Suzuki-Miyaura cross-coupling reaction and evaluated for antiprotozoal activity against Plasmodium falciparum and Leishmania donovani. Several compounds were found to strongly inhibit the prolifera
Autor:
Anton Savitsky, Laszlo Jicsinszky, Sandrine Chenesseau, Dmitriy N. Polovyanenko, David Bardelang, Paul Tordo, Sylvain R. A. Marque, Klaus Möbius, Elena G. Bagryanskaya, Jean-Pierre Finet, Hakim Karoui
Publikováno v:
Applied Magnetic Resonance. 36:181-194
In a recent paper (Bardelang et al. in J Org Chem 71:7657–7667, 2006), the deep inclusion of the TIPNO (1-phenyl-2-methylpropyl-1,1-dimethylethyl-2-nitroxide) free radical attached to a permethylated β-cyclodextrin (TRIMEB) into its cavity was que
Autor:
Véronique Bourgarel-Rey, Sébastien Combes, Jean-Pierre Finet, Etienne Daras, Olga G. Ganina, Alexey Yu. Fedorov, Irina P. Beletskaya, Alexey N. Andresyuk, Vincent Peyrot
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:8806-8812
A series of syn-restricted polymethoxylated 4-heteroarylcoumarins—the isostuctural analogs of combretastatin A-4—was synthesized by Suzuki–Miyaura cross-coupling reaction and evaluated for antiproliferative activity. The 4-(1-methyl-1H-indol-5-
Autor:
Soazig Douillard, Udom Kokpol, Jean-Pierre Finet, Nicolas Vidal, Sébastien Combes, Vincent Peyrot, Warinthorn Chavasiri, Sujittra Deesamer
Publikováno v:
Tetrahedron. 63:12986-12993
Mucronulatol 1 and violanone 2 isolated from Dalbergia oliveri Gamble, and the corresponding isoflavone 3 were prepared by ligand coupling reactions involving organolead reagent. Biological studies have shown a significant cytotoxic effect against an
Autor:
Aleksey V. Gushchin, Viktor A. Dodonov, Vladimir V. Semenov, Elena Yu. Ladilina, Georgii K. Fukin, Irina V. Zhdanovich, Jean-Pierre Finet
Publikováno v:
Journal of Organometallic Chemistry. 692:5701-5708
Pentavalent bis(triorganosiloxy)triphenylantimony derivatives, Ph3Sb(OSiR3)2 (R = Me, Ph), were synthesized by reaction of triphenylantimony with trimethyl- or triphenylsilanol in the presence of tert-butylhydroperoxide by the mild reaction condition
Autor:
Jean-Pierre Finet, Christiane Bernard-Henriet, Sylvain R. A. Marque, Robert Lauricella, Paul Tordo, Yves Berchadsky
Publikováno v:
Chemistry - A European Journal. 12:7084-7094
Persistent noncyclic phosphoranyl radicals have been prepared and observed by electron paramagnetic resonance (EPR) for the first time. They were obtained by UV-photolysis of a solution containing a bis(trialkylsilyl) peroxide (R = Me, Et) and a tris
Autor:
Alexey Yu. Fedorov, Jean-Pierre Finet
Publikováno v:
Journal of Organometallic Chemistry. 691:2386-2393
Tris-(polymethoxyphenyl)bismuth diacetate and dichloride derivatives react with C-nucleophiles in basic medium, as well as with N- and O-nucleophiles under copper catalysis to give good to high yields of the corresponding C-, N- and O-arylation produ
Autor:
Jean-Pierre Finet, Antal Rockenbauer, Karol Banaszak, Inga Biskupska, David Bardelang, Hakim Karoui, Paul Tordo
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2006, 4, pp.2874-2882
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2006, 4, pp.2874-2882
Organic & Biomolecular Chemistry, 2006, 4, pp.2874-2882
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2006, 4, pp.2874-2882
The free radical trapping properties of eight 5-alkoxycarbonyl-5-methyl-1-pyrroline N-oxide (EMPO) type nitrones and those of 5,5-dimethyl-1-pyrroline N-oxide (DMPO) were evaluated for trapping of superoxide anion radicals in the presence of 2,6-di-O
Publikováno v:
Synthesis: Journal of Synthetic Organic Chemistry
Synthesis: Journal of Synthetic Organic Chemistry, 2005, 15, pp.2527-2532. ⟨10.1055/s-2005-872106⟩
SYNTHESIS
SYNTHESIS, Georg Thieme Verlag, 2005, 15, pp.2527-2532. ⟨10.1055/s-2005-872106⟩
Synthesis: Journal of Synthetic Organic Chemistry, 2005, 15, pp.2527-2532. ⟨10.1055/s-2005-872106⟩
SYNTHESIS
SYNTHESIS, Georg Thieme Verlag, 2005, 15, pp.2527-2532. ⟨10.1055/s-2005-872106⟩
New spiro compounds, 8-oxotheaspiranes analogues and dihydro equivalents possessing a partly fluorinated ring, are obtained from 5-(co-iodoperfluoropropyl)furan-3(2H)-one and unsaturated compounds through an annulation process (favored 6-exotrig). Yi