Gating of Substrate Access and Long-Range Proton Transfer in Escherichia coli Nitrate Reductase A: The Essential Role of a Remote Glutamate Residue

Autor: Axel Magalon, Frédéric Biaso, Julia Rendon, Stéphane Grimaldi, Farida Seduk, Marlon Sidore, Bruno Guigliarelli, Sinan Al-Attar, Jean-Pierre Duneau

Publikováno v: ACS Catalysis
ACS Catalysis, 2021, 11 (23), pp.14303-14318. ⟨10.1021/acscatal.1c03988⟩
ACS Catalysis, American Chemical Society, 2021, 11 (23), pp.14303-14318. ⟨10.1021/acscatal.1c03988⟩

International audience; The Mo/W-bisPGD enzyme superfamily comprises a vast number of mononuclear molybdenum and tungsten enzymes that catalyze a great diversity of vital reactions in prokaryotes. In the past decades, much attention has been devoted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a51f301d03e1b31b6d9d6cde0f3258
https://doi.org/10.1021/acscatal.1c03988

The lipid environment of Escherichia coli Aquaporin Z

Autor: Marlon Sidore, James N. Sturgis, Victoria Schmidt, Jean-Pierre Duneau, Cherine Bechara

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (2), pp.431-440. ⟨10.1016/j.bbamem.2018.10.017⟩
Biochimica et Biophysica Acta:Biomembranes, 2019, 1861 (2), pp.431-440. ⟨10.1016/j.bbamem.2018.10.017⟩

International audience; In this study, we have investigated the lipids surrounding AqpZ, and the effects of a destabilizing mutation W14A (Schmidt and Sturgis, 2017) on lipid protein interactions. In a first approach, we used Styrene Maleic Acid copo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785e18652ace3171458659bdce257d59
https://doi.org/10.1016/j.bbamem.2018.10.017

Tryptophan-mediated Dimerization of the TssL Transmembrane Anchor Is Required for Type VI Secretion System Activity

Autor: Laure Journet, Abdelrahim Zoued, Eric Cascales, Jean-Pierre Duneau, Alexandre P. España, Françoise Guerlesquin, Eric Durand

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, 2018, 430 (7), pp.987-1003. ⟨10.1016/j.jmb.2018.02.008⟩
Journal of Molecular Biology, Elsevier, 2018, 430 (7), pp.987-1003. ⟨10.1016/j.jmb.2018.02.008⟩

The type VI secretion system (T6SS) is a multiprotein complex used by bacteria to deliver effectors into target cells. The T6SS comprises a bacteriophage-like contractile tail structure anchored to the cell envelope by a membrane complex constituted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833535f258dafd31630e262bb0f97114
https://pubmed.ncbi.nlm.nih.gov/29458124

A Dimerization Hierarchy in the Transmembrane Domains of the HER Receptor Family

Autor: James N. Sturgis, Attila P. Vegh, Jean-Pierre Duneau

Publikováno v: Biochemistry. 46:2010-2019

Bitopic membrane proteins offer an opportunity for studying transmembrane domain interactions without the structural complexity inherent to multitopic integral membrane proteins. To date, only homomeric associations have been extensively studied quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99580ef917aea9d1b2d19789536f1be
https://doi.org/10.1021/bi061436f

Ptuba: a tool for the visualization of helix surfaces in proteins

Autor: Jaime Arce Lopera, James N. Sturgis, Jean-Pierre Duneau

Publikováno v: Journal of Molecular Graphics and Modelling. 23:305-315

Projection of transmembrane helices using a Uniform B-spline Algorithm is a tool for the visualization of interactions between helices in membrane proteins. It allows the user to generate projections of 3D helices, no matter what their deviations fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fe0a4d86328d981abeef94af2cf2ca
https://doi.org/10.1016/j.jmgm.2004.10.004