Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jean-Pierre Dollé"'
Autor:
Douglas H. Smith, Jean-Pierre Dollé, Kamar E. Ameen-Ali, Abigail Bretzin, Etty Cortes, John F. Crary, Kristen Dams-O’Connor, Ramon Diaz-Arrastia, Brian L. Edlow, Rebecca Folkerth, Lili-Naz Hazrati, Sidney R. Hinds, Diego Iacono, Victoria E. Johnson, C. Dirk Keene, Julia Kofler, Gabor G. Kovacs, Edward B. Lee, Geoffrey Manley, David Meaney, Thomas Montine, David O. Okonkwo, Daniel P. Perl, John Q. Trojanowski, Douglas J. Wiebe, Kristine Yaffe, Thomas McCabe, William Stewart
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Efforts to characterize the late effects of traumatic brain injury (TBI) have been in progress for some time. In recent years much of this activity has been directed towards reporting of chronic traumatic encephalopathy (CTE) in former conta
Externí odkaz:
https://doaj.org/article/29288ff2f7cb4df5a26fd50f38a60256
Autor:
Jean-Pierre Dollé, Jeffrey M. Rodgers, Kevin D. Browne, Thomas Troxler, Feng Gai, Douglas H. Smith
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 161-169 (2018)
Although N-acetylaspartate (NAA) has long been recognized as the most abundant amino acid in neurons by far, its primary role has remained a mystery. Based on its unique tertiary structure, we explored the potential of NAA to modulate aggregation of
Externí odkaz:
https://doaj.org/article/954446c0e12f4a08a35130e4259893a7
Autor:
Ahmed Albayar, Patricia Zadnik Sullivan, Douglas H. Smith, Zi-Xing Xu, Justin Bianchini, D. Kacy Cullen, Jean-Pierre Dollé, Gisele Hansel, Ali K. Ozturk
Publikováno v:
Restorative Neurology and Neuroscience. 38:1-9
Background Spinal cord injury (SCI) patients represent a heterogeneous group, with injuries ranging from partial compression to complete transection. Patients with complete injuries are unlikely to exhibit recovery and suffer from paralysis as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d735e13cf94b47ed5adacfba39953f85
https://doi.org/10.3233/rnn-190933
https://doi.org/10.3233/rnn-190933
Autor:
John D. Arena, Aayush Kant, Victoria E. Johnson, Jean-Pierre Dollé, Vivek B. Shenoy, Douglas H. Smith
Publikováno v:
Proc Natl Acad Sci U S A
Damage to the microtubule lattice, which serves as a rigid cytoskeletal backbone for the axon, is a hallmark mechanical initiator of pathophysiology after concussion. Understanding the mechanical stress transfer from the brain tissue to the axonal cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447e81781cc6e0b2da5869e153bf95c9
https://doi.org/10.1073/pnas.2024961118
https://doi.org/10.1073/pnas.2024961118
Autor:
John F. Crary, Kristine Yaffe, Kamar E. Ameen-Ali, Brian L. Edlow, Douglas H. Smith, Thomas J. Montine, Abigail C. Bretzin, Victoria E. Johnson, Daniel P. Perl, Thomas McCabe, Sidney R. Hinds, Lili-Naz Hazrati, Gabor G. Kovacs, Edward B. Lee, Julia Kofler, Rebecca D. Folkerth, Ramon Diaz-Arrastia, Kristen Dams-O'Connor, Geoffrey T. Manley, John Q. Trojanowski, Douglas J. Wiebe, David O. Okonkwo, William Stewart, C. Dirk Keene, Jean-Pierre Dollé, Etty Cortes, David F. Meaney, Diego Iacono
Publikováno v:
Acta neuropathologica communications, vol 9, iss 1
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Acta Neuropathologica Communications
Efforts to characterize the late effects of traumatic brain injury (TBI) have been in progress for some time. In recent years much of this activity has been directed towards reporting of chronic traumatic encephalopathy (CTE) in former contact sports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c4aa77d17432161f365563a37f75f8
https://doi.org/10.1186/s40478-021-01122-9
https://doi.org/10.1186/s40478-021-01122-9
Autor:
Vivek B. Shenoy, Farid Alisafaei, Ze Gong, Douglas H. Smith, Jean-Pierre Dollé, Victoria E. Johnson
Publikováno v:
Biophys J
Diffuse axonal injury is a primary neuropathological feature of concussion and is thought to greatly contribute to the classical symptoms of decreased processing speed and memory dysfunction. Although previous studies have investigated the injury bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8af885e749ac66e790f67dd988567e3
https://europepmc.org/articles/PMC7567985/
https://europepmc.org/articles/PMC7567985/
REVERSAL OF FIBRONECTIN-INDUCED HIPPOCAMPAL DEGENERATION WITH ENCAPSULATED MESENCHYMAL STROMAL CELLS
Autor:
Casey J. Moure, Martin L. Yarmush, Rene S. Schloss, Jeffrey Barminko, Sai Y. Veruva, Jean-Pierre Dollé
Publikováno v:
Nano LIFE. 3(4)
Mesenchymal stromal cells (MSC) can promote tissue protection following injury, in part by modulating inflammatory cell responses. The aim of this study was to investigate the potential tissue protective properties of encapsulated MSCs (eMSC) in an o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0029f55e9eb07e0d3e504e6341e082ec
https://pubmed.ncbi.nlm.nih.gov/29725486
https://pubmed.ncbi.nlm.nih.gov/29725486
Autor:
Andrew H Jaye, Douglas H. Smith, Stewart A. Anderson, Jean-Pierre Dollé, Vivek B. Shenoy, Hossein Ahmadzadeh
Since traumatic axonal injury (TAI) is implicated as a prominent pathology of concussion, we examined potential sex differences in axon structure and responses to TAI. Rat and human neurons were used to develop micropatterned axon tracts in vitro tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196f5498397ef1cd57d89ef1f368a807
https://europepmc.org/articles/PMC6495524/
https://europepmc.org/articles/PMC6495524/
Publikováno v:
Annual Review of Biomedical Engineering. 13:91-126
In vitro models of traumatic brain injury (TBI) are helping elucidate the pathobiological mechanisms responsible for dysfunction and delayed cell death after mechanical stimulation of the brain. Researchers have identified compounds that have the pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fab0395a1d0e1dd7707b0bac0b9d13
https://doi.org/10.1146/annurev-bioeng-071910-124706
https://doi.org/10.1146/annurev-bioeng-071910-124706
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 315:1220-1227
Nerve growth factor (NGF) is a well known neurotropic and neurotrophic agonist in the nervous system, which recently was shown to also induce angiogenic effects in endothelial cells (ECs). To measure NGF effects on the migration of cultured ECs, an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d05ab54ab564df3459ee74fd29b6d3
https://doi.org/10.1124/jpet.105.093252
https://doi.org/10.1124/jpet.105.093252