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pro vyhledávání: '"Jean-Pierre Delatinne"'
Autor:
Magali Palacio, Célal Ates, Arnaud Schule, Jean-Pierre Delatinne, Jimmy Stofferis, Bruno Martin, Steven Lloyd
Publikováno v:
Organic Process Research & Development. 14:1008-1014
In this article we describe the strategy adopted to minimize the risk of acetamide presence in zaurategrast sulfate drug candidate. A risk of acetamide formation (a potential genotoxic impurity) was identified in the API formation step of the process