Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Jean-Pierre Couty"'
1
Akademický článek
LKB1 as a Gatekeeper of Hepatocyte Proliferation and Genomic Integrity during Liver Regeneration
Autor: Vanessa Maillet, Nadia Boussetta, Jocelyne Leclerc, Véronique Fauveau, Marc Foretz, Benoit Viollet, Jean-Pierre Couty, Séverine Celton-Morizur, Christine Perret, Chantal Desdouets
Publikováno v: Cell Reports, Vol 22, Iss 8, Pp 1994-2005 (2018)
Summary: Liver kinase B1 (LKB1) is involved in several biological processes and is a key regulator of hepatic metabolism and polarity. Here, we demonstrate that the master kinase LKB1 plays a dual role in liver regeneration, independently of its majo
Externí odkaz: https://doaj.org/article/aaefdd6b409e402988f53a843dabb732
Zobrazit plný text záznamu
2
Lect2 Controls Inflammatory Monocytes to Constrain the Growth and Progression of Hepatocellular Carcinoma
Autor: Stefano Caruso, Anne-Marie Crain-Denoyelle, Marie Anson, Antoine L’Hermitte, Jessica Zucman-Rossi, Séverine Celton-Morizur, Sandrine Pham, Mathilde Cadoux, Gabrielle Couchy, Satoshi Yamagoe, Chantal Desdouets, Jean-Pierre Couty
Publikováno v: Hepatology
Hepatology, Wiley-Blackwell, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
Hepatology, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
International audience; Leukocyte cell-derived chemotaxin-2 (LECT2) was originally identified as a hepatocyte-secreted chemokine-like factor and a positive target of β-catenin signaling. Here, we dissected out the mechanisms by which LECT2 modulates
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c4495c89df1193f7b7abcec6ff2868
https://doi.org/10.1002/hep.30140
Zobrazit plný text záznamu
3
Expression of NKG2D ligands is downregulated by beta-catenin signaling and associates with HCC aggressiveness
Autor: Rozenn Riou, Angélique Gougelet, Robin Loesch, Cong Trung Nguyen, Nadia Guerra, Julien Calderaro, Jean-Pierre Couty, Jessica Zucman-Rossi, Sandrine Pham, Chantal Desdouets, Stefano Caruso, Sabine Colnot, Séverine Celton-Morizur, Mathilde Cadoux, Céline Pophillat
Publikováno v: Journal of Hepatology
Journal of Hepatology, Elsevier, 2021, ⟨10.1016/j.jhep.2021.01.017⟩
Background & Aims The NKG2D system is a potent immunosurveillance mechanism in cancer, wherein the activating NK cell receptor (NKG2D) on immune cells recognises its cognate ligands on tumour cells. Herein, we evaluated the expression of NKG2D ligand
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc5181677241666a18c0389bba58fb0
https://hal.archives-ouvertes.fr/hal-03140512
Zobrazit plný text záznamu
4
Hepatocellular carcinoma in the context of non-alcoholic steatohepatitis (NASH): recent advances in the pathogenic mechanisms
Autor: Marie Lequoy, Jean-Pierre Couty, Christèle Desbois-Mouthon, Elia Gigante
Publikováno v: Hormone Molecular Biology and Clinical Investigation
Hormone Molecular Biology and Clinical Investigation, de Gruyter, 2020, 41 (1), ⟨10.1515/hmbci-2019-0044⟩
Hormone Molecular Biology and Clinical Investigation, 2020, 41 (1), ⟨10.1515/hmbci-2019-0044⟩
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is particularly aggressive and is one of the leading causes of cancer mortality. In recent decades, the epidemiological landscape of HCC has undergone significant changes. Wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f15793e44911af372fefd3ffe6c1f07
https://doi.org/10.1515/hmbci-2019-0044
Zobrazit plný text záznamu
5
Hepatospecific ablation of p38α MAPK governs liver regeneration through modulation of inflammatory response to CCl4-induced acute injury
Autor: Nadia Boussetta, Sandrine Pham, Jean-Pierre Couty, Chantal Desdouets, Séverine Celton-Morizur, Manon Fortier, Mathilde Cadoux, Romain Donne
Publikováno v: Scientific Reports
Scientific Reports, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Nature Publishing Group, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Mammalian p38α MAPK (Mitogen-Activated Protein Kinase) transduces a variety of extracellular signals that regulate cellular processes, such as inflammation, differentiation, proliferation or apoptosis. In the liver, depending of the physiopathologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78dc145917ceaa4d5213e2c5a66d3f4e
https://doi.org/10.1038/s41598-019-51175-z
Zobrazit plný text záznamu
6
Hepatospecific ablation of p38α MAPK governs liver regeneration through modulation of inflammatory response to CCl
Autor: Manon, Fortier, Mathilde, Cadoux, Nadia, Boussetta, Sandrine, Pham, Romain, Donné, Jean-Pierre, Couty, Chantal, Desdouets, Séverine, Celton-Morizur
Publikováno v: Scientific Reports
Mammalian p38α MAPK (Mitogen-Activated Protein Kinase) transduces a variety of extracellular signals that regulate cellular processes, such as inflammation, differentiation, proliferation or apoptosis. In the liver, depending of the physiopathologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67ced7fa79129183f83cbca6229b3dec
https://pubmed.ncbi.nlm.nih.gov/31601995
Zobrazit plný text záznamu
7
Polyploidy spectrum: a new marker in HCC classification
Autor: Jean-Pierre Couty, Valérie Paradis, Géraldine Gentric, Miguel Albuquerque, Romain Donne, Christophe Klein, Chantal Desdouets, Antoine L’Hermitte, Jessica Zucman-Rossi, Julien Calderaro, Thomas Guilbert, Mathilde Cadoux, Gabrielle Couchy, Stefano Caruso, Séverine Celton-Morizur, Myriam Bou-Nader
Publikováno v: Gut
Gut, BMJ Publishing Group, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
Gut, BMJ Publishing Group, 2020, 69 (2), pp.355-364. ⟨10.1136/gutjnl-2018-318021⟩
Gut, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
ObjectivesPolyploidy is a fascinating characteristic of liver parenchyma. Hepatocyte polyploidy depends on the DNA content of each nucleus (nuclear ploidy) and the number of nuclei per cell (cellular ploidy). Which role can be assigned to polyploidy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee5f7b20cd3a1905f8faaad785675cd
https://hal.sorbonne-universite.fr/hal-02102441/file/gutjnl-2018-318021.full.pdf
Zobrazit plný text záznamu
10
Hepatokines: unlocking the multi-organ network in metabolic diseases
Autor: Catherine Postic, Jean-Pierre Couty, Alison Iroz
Publikováno v: Diabetologia. 58:1699-1703
In the face of urbanisation, surplus energy intake, sedentary habits and obesity, type 2 diabetes has developed intoamajorhealthconcernworldwide.Commonlyoverlooked in contemporary obesity research, the liver is emerging as a central regulator of whol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3dfcf1f4d03a9b049d8525debdfd5c67
https://doi.org/10.1007/s00125-015-3634-4
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje